Search PubMed⌕ Search

Biomedical subjects

W Szelenberger

Publications and source records attributed to W Szelenberger.

34 records · Page 2Linked to original sources
PubMedDate not supplied

Pharmaco-EEG analysis by means of FFT and FAD.

The EEG effects of a single oral dose of diazepam, amitriptyline and pernazine were studied in 26 healthy volunteers. The EEG analysis was performed by means of FFT and a new parametric method FAD. The results indicate that the FAD method reveals drug changes significantly more often than does the FFT analysis and that the medication effects are more clearly defined by the FAD. The method can be useful in the assessment of the subtle effects of the psychotropic drugs.

Administration, Oral↗
PubMedDate not supplied

[Psychopathological characteristics of the consequences of obstructive sleep apnea prior to and 3 months after therapy].

The aim of the research was to discover the level of change observed in cognitive functions and personality variables in patients ill with obstructive sleep apnea prior to and after CPAP treatment. Data was collected from 20 male patients ill with a severe form of obstructive sleep apnea whose physiological symptoms were correlated with the results of cognitive functions and personality variables. It was concluded that obstructive sleep apnea patients have lowered; attention, concentration, speed of learning verbal and visual stimuli and speed of learning visual-motor tasks. An increased level of depression was noted together with increased anxiety and psychological tension. In half of the group irregular EEG recordings and a pathological result on the Benton Test suggests organic damage to the CNS. These changes were negatively correlated with amounts of REM and 3 + 4 NREM sleep, but were positively correlated with the level of sleep hypoxemia. The results suggest that after 3 months of CPAP treatment affect improved significantly. The observed tendency for cognitive functions to improved was not statistically significant.

Adult↗
PubMedDate not supplied

[Treatment of delirium tremens with quick administration of diazepam].

In this efficacy the study of diazepam loading-dose treatment of delirium tremens was evaluated in comparison with traditional therapeutic methods. Experimental and control groups consisted of 42 and 40 patients respectively. The severity of the withdrawal symptoms was evaluated from clinical status, in the experimental group CIWA-A score was also employed. Study results suggest high efficacy of the loading-dose method, which was characterized by significant shortening of psychosis duration (five times shorter in experimental vs. control group). The method turned out to be safe, no complications were observed during and after the treatment.

Adult↗
PubMedDate not supplied

[Continuous attention in schizophrenic patients].

Continuous Attention Task (CAT) was applied in a group of schizophrenic patients (N = 35), patients with schizoaffective disorder (N = 17), major depressive episode (N = 14), chronic alcohol dependence (N = 16) and healthy volunteers (N = 31). Moreover, the patients were examined with the Positive and Negative Syndrome Scale (PANSS) and the intelligence test (DMI). The results of the CAT test were significantly better in the group of healthy subjects and depressive patients in comparison to the other groups. There were no differences in CAT test between the schizophrenic, schizoaffective and alcohol dependent patients. There were no differences in CAT between the depressive patients and the healthy subjects either. The differences in the CAT results could not be contributed to the PANSS scores. The depressive patients got higher scores on the logical multiplication scale (MN) and the analogy scale (AN) of intellectual ability test (DMI) as compared to the schizophrenic patients, and higher scores on the MN scale in comparison to the alcohol dependent subjects. It was concluded that the deficits in CAT scores could be connected with the deficits in intellectual functions.

Adult↗