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Biomedical subjects

W Strupler

Publications and source records attributed to W Strupler.

At least 19 recordsLinked to original sources
PubMed1983

Thyroid cancer in childhood.

A rare case of a papillary thyroid cancer in a young boy is reported. At the age of 8 years a rapidly growing tumour of the right antero-lateral neck region was detected. Biopsy revealed a cervical lymph node metastasis of a papillary thyroid carcinoma. Any adequate therapy was rejected by the patient's father. After two years of delay, at the age of ten, a severe dyspnoea urged to an emergency tracheotomy. The further investigations revealed a bilateral partly papillary, partly follicular and partly anaplastic thyroid carcinoma with infiltration and compression of the cervical trachea and the cricoid and with right recurrent nerve paralysis. The thyroid cancer was classified as T3N2bM0. To save the boy's life an extensive operation was performed with total extirpation of the thyroid gland and the adjacent tissues, total laryngectomy and resection of the cervical trachea, combined with bilateral neck dissection. The patient has been given no other treatment than hormone substitution during 16 years after surgery. The patient grew up normally and stayed recurrence-free. As far as we could find in world literature, this is the youngest patient with total laryngectomy, partial resection of the trachea, total thyroidectomy and bilateral neck dissection.

Carcinoma, Papillary↗
PubMed1979

[Styloid syndrome; Sluder's syndrome; Charlin's syndrome].

The styloid syndrome is caused by an irritation of the glossopharyngeal nerve from an excessive development of the styloid apophysis. Treatment consists of the resection of the same. The Sluder syndrome represents a nevralgy with origin in the sphenopalatine ganglion and a dysfunction of the parasympathetic system. The Charlin syndrome, much less frequent, manifests itself by pains in the territory of the nasociliar nerve and the ciliar ganglion.

Bone Diseases↗
PubMed1978

[Meaningful possibilities of palliative therapy of incurable mouth and pharyngeal neoplasms and their recurrence].

In incurable cancer of the mouth and oropharynx, reasonable palliative therapy should render the patient's remaining life-span worth living. The following problems impair tumor patient's well-being: 1. pain, 2. ingestive and respiratory difficulties, 3. aspect, 4. odor, 5. psychic trauma resulting from 3 and 4. Pain, either caused by the tumor itself or as a reaction to irradiation or inflammatory response, is of primary importance. Impairment of ingestion, respiration, and speech diminishes the quality of life. Disfigurement of the face or a penetrating odor may sometimes cause additional psychic stress. Besides palliative radio- and chemotherapy, in certain cases palliation can be obtained by surgery, which may reduce the size of a cosmetically disturbing tumor mass or create a clean wound surface easier to care for than a necrotic surface. Furthermore, painful neuralgic nerve branches may be severed. Severe lymphedema of the face and neck may be improved by lumbo-peritoneal shunt operation. Most recently, cryosurgery has won an established place in the management of these problems, although certain restrictions must be observed. Superficial recurrences can be treated without further mutilation of the patient. Painful areas of the tumor can be eradicated. Recurrences in the hypopharynx, which are accessible with difficulty only, can be treated with a cryosonde with little harm to an already impaired patient. Multiple tumor lesions can be iced at the same time. Among the reasonable palliative methods of treatment, synchronized irradiation and chemotherapy as well as implantation of solid radioactive substances must be mentioned.

Analgesia↗