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Biomedical subjects

W Stremmel

Publications and source records attributed to W Stremmel.

At least 289 records · Page 16Linked to original sources
PubMed1979

[The effect of somatostatin on the ileocecal sphincter (ICS) before and after extensive small bowel resection].

The ileocoecal sphincter pressure of rabbits was studied under somatostatin infusion before and after subtotal small bowel resection. Before resection, somatostatin increased the pressure necessary to pass fluid through this zone according to the applied doses. Seven days after resection, a decrease in the ileocoecal sphincter pressure was found, which could not be affected by somatostatin infusion. One year after resection, the reflux pressure was again normal, and the somatostatin effect was similar as to that before resection.

Animals↗
PubMed1978

[Peritoneal drainage without antibiotics (author's transl)].

The mortality of generalized peritonitis in serious. The drainage of the peritoneal cavity for diffuse peritonitis is essential but difficult, and it should be combined with peritoneal lavage. The drainage system must be properly adapted to the intraperitoneal liquid circulation. The local use of antibiotics is not indicated. Systemic administration is obvious, because in about 80% of cases, it is an anaerobic infection with Bacteroides fragilis, a dreadfully tough organism, which impairs the function of organs such as lung, heart, kidney, brain, and liver.

Drainage↗
PubMed1977

[Hormonal and pharmacological modification of the ileocecal sphincter].

Ileocecal shincter (ICS) pressure was evaluated in response to hormonal and pharmacological stimuli in rabbits. The effect of exogeneous gastrin (pentagastrin) and glucagon, metoclopramide and neostigmin on the ICS pressure was studied. Gastrin, glucagon and metoclopramide increased the pressure whereas neostigmin lowered it. These results suggest that this junctional zone is not only a valve but a real shincter, which is affected by gastrointestinal hormones and pharmacological substances. Further examinations are necessary to study the role of the ICS after gastrointestinal surgery.

Animals↗
PubMed1977

[The postvagotomy syndrome (author's transl)].

The postvagotomy syndrome following the operative section of the vagus nerves is characterized by diarrhoea. The incidence of diarrhoea after truneal vagotomy is about 25%, after selective vagotomy 15% and after proximal selective vagotomy only 2%. The possible pathogenetic factors are accelerated passage through the gut, disturbed bile acid metabolism, the bacterical inflammation of the small intestine, and enterohormonal dysregulation. A cholongenetic diarrhoea is probable because after vagotomy the excretion of bile acids is increased and the diarrhoea is interrupted after administring cholestyramin, which absorbs the bile salts in the intestine. In addition the pathogenetic role of an impaired function of the ileocecal valve should be discussed.

Bile Acids and Salts↗
PubMed1976

[Bis(monoacylglycero)phosphate--a marker lipid of secondary lysosomes? (AUTHOR'S TRANSL)].

Rats were treated with triton, dextran, silver and iron. The lysosomal fractions from their livers were isolated and the lipids analysed. (MAG)2P could be detected in every phospholipid fraction, accounting for 6-28 per cent of the total lipid phosphorus. The composition of the fatty acids from this acidic glycerophospholipid shows an extraordinarily high amount of polyenoic fatty acids (58-82 per cent of the total), of which docosahexaenoic acid is a main compound.

Acid Phosphatase↗
PubMed1975

[The growth hormone in craniocerebral injury].

Following head injuries with various degrees of cerebral trauma increased STH-concentrations of plasma can be measured. Blood glucose values are elevated reflecting a diabetic metabolism lead to a suppressive effect of increased STH-blood levels. In general it can be stated, that a stress situation is followed by an increase of STH-secretion despite of elevated blood glucose concentrations. The reasons may be: 1. increased liberation of catecholamines, 2. an intracellular glucose deficit due to disturbed glucose utilisation, 3. alteration of regional blood flow after trauma.

Adolescent↗
PubMed1975

[Effect of arginine on insulin liberation during intra-abdominal operations].

During abdominal surgery the basal and glucose stimulated insulin secretion rate is reduced. An arginine-infusion of 0,5 g/kg over 30 minutes is able to stimulate the basal as well as the glucose stimulated insulin secretion under stress condition. A synergism between the effect of arginine and blood glucose concentration concerning the influence on insulin secretion can be proven. The results are important for the postoperative (posttraumatic) infusion therapy.

Abdomen↗
PubMed1975

[An unusual cause of an "intramural" gas collection in the right colon (author's transl)].

A case of subserous gas collection in the right colon following surgical repair of an iatrogenic uterus perforation is presented. The patient showed an ileus-like roentgen symptomatology when ischemic necrosis of the bowel was suspected. Laparatomy demonstrated the remainder of the gas collection in the area of the right pelvis extending retroperitoneally towards the right colon, thus presenting intramural pneumatosis. Therefore the differential diagnosis of intramural gas collection as a sign of ischemic bowel necrosis has to include the harmless subserous pneumatosis following abdominal trauma (especially iatrogenic uterus perforation).

Abdominal Injuries↗