Biomedical subjects

W Straube

Publications and source records attributed to W Straube.

At least 127 records · Page 7Linked to original sources

PubMed1975

[A new rapid test for diagnosing micro-haematuria, compared with results of microscopic examination].

Micro-haematuria may be difficult to diagnose because the usual sediment methods may be inadequate and test strips may in practice not be sensitive enough. The demarcation between normal and pathological RBC excretion is, therefore, not always clearly established. A new test strip (Sangur-Test) has its lower limit of positive results at 1 000 RBC/ml urine and physiological ranges of RBC excretion could be distinguished from micro-haematuria with satisfactory accuracy. Comparative tests of 637 freshly voided urine specimens in routine diagnosis produced no false-negative results and in only a small percentage of cases recorded a higher RBC concentration than the ten-field sediment method.

Blood Sedimentation↗

PubMed1975

[Therapy of the carcinoma of the prostate and case control (III) (Author's transl)].

In a third information of our long-term study with now 304 cases we report on 54 cases with monotherapy-only orchiectomy, only hormones and combination of boths. With it the rectal palpable results have coincided significantly with the histological findings in all 3 therapeutic forms. As for the therapeutic result no difference is to be seen either histological or clinical after a 3 years' observation period. We cannot tell anything now about optimal methods of treatment with regard to the histological starting material. In all 3 therapeutic forms we observed regressions to stage O. The smallest plasma-testosteron concentration was found after orchiectomy, where no increase was recorded during the whole observation period.

Adenocarcinoma↗

PubMed1975

[Immunological aspects in EPH gestosis].

On the base of the fundamental knowledge on immunological reactions in the normal pregnancy the disease of the EPH-gestosis is described from the immunological viewpoint. The following facts may be significant: 1. The increased occurence of specific and nonspecific crossreacting antibodies against liver, kidney and placental tissue in the blood of pregnant women and puerperas. 2. The increased occurence of placental infarctions and throphoblastic defects as well as fibrinoid deposits in the placenta, the arteriols and in the kidney. 3. Changes in the protein composition of blood. 4. The changed maternal cell-mediated immunity.

Alkaline Phosphatase↗

PubMed1975

[Immunochemical demonstration of soluble antigens in the protein fractions of placental tissue].

Protein fractions were prepared from placental tissue by homogenization, ammonium sulfate fractionation, gel filtration and ion exchange chromatography. The antigens detected in these fractions by absorbed antisera against placental tissue and pregnancy serum partly occur in the pregnancy and fetal serum too. The other antigens, which are found neither in pregnancy serum nor in fetal serum, could be specific for placental tissue. Their possible significance is discussed.

Antigens↗

PubMed1975

[Isolation of "pregnancy-zone" proteins using immuno absorbents and study of possible enzyme activities].

The purification of the pregnancy zone protein by means of immunoadsorbents is described. The pregnancy zone protein antibody was isolated from an absorbed rabbit antiserum and coupled with CNBr-activated sepharose. The pregnancy zone protein was isolated from pregnancy serum by the specific antibody cross-linked with sepharose. Contaminating serum proteins were eliminated by "inverse" immunoadsorption using antibodies against these proteins coupled with sepharose. An immunoelectrophoretically pure pregnancy zone protein was obtained. By means of a combination of immunoprecipitation and enzyme reaction in agar gel could be excluded that the pregnancy zone protein possesses activities of the following 11 enzymes: ceruloplasmin, leucine amino peptidase, alkaline phosphatase, carboxylic esterase, lactate dehydrogenase, malate dehydrogenase, glycerophosphate dehydrogenase, glucose-6-phosphat-dehydrogenase, cholinesterase, acetyl cholinesterase and oxytocinase.

Adsorption↗

PubMed1974