Metabolism of sphingosine bases. XVII. Stereospecificities in the introduction of the 4t-double bond into sphinganine yielding 4t-sphingenine (sphingosine).
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Animals↗
Biomedical subjects
W Stoffel
Publications and source records attributed to W Stoffel.
Studies on the biosynthesis and degradation of sphingosine bases.
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Alkalies↗
Correlation of in vivo and in vitro phase transitions of membrane lipids in Escherichia coli.
A double mutant of Escherichia coli unable to synthesize or degrade unsaturated fatty acids can incorporate fatty acids with various hydrocarbon chain structures into the membrane phospholipids. The temperature characteristic of three physiological properties of cells grown with different fatty acids (growth, respiration, and efflux of thiomethylgalactoside) is compared with the physical properties of the isolated phosphatidylethanolamines in monolayers at an air-water interface. Breaks in the temperature characteristic of the properties measured in vivo correspond to phase transitions in the lipid films from a liquid-expanded to a condensed form. It is concluded that a liquid-like state of the lipid phase is required for proper membrane function.
Carbon Isotopes↗
Metabolism of sphingosine bases. 13. Enzymatic synthesis of 1-phosphate esters of 4t-sphingenine (sphingosine), sphinganine (dihydrosphingosine), 4-hydroxysphinganine (phytosphingosine) and 3-dehydrosphinganine by erythrocytes.
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Amino Alcohols↗
Metabolism of sphingosine bases. XV. Enzymatic degradation of 4t-sphingenine 1-phosphate (sphingosine 1-phosphate) to 2t-hexadecen-1-al and ethanolamine phosphate.
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Alcohol Oxidoreductases↗
Biochemical analysis of the pinocytotic process. I. Isolation and chemical composition of the lysosomal and the plasma membrane of the rat liver cell.
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Animals↗
Enzymatic studies on the mechanism of the retroconversion of C22-polyenoic fatty acids to their C20-homologues.
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Alcohol Oxidoreductases↗
Biochemical analsis of the inocytotic process. II. Comparison of some enzymes of the lysosomal nd the plasma membrane of the rat liver cel.
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Acid Phosphatase↗
Metabolism of sphingosine bases. XIV. Sphinganine (dihydrosphingosine), an effective donor of the alk-1-enyl chain of plasmalogens.
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Alcohol Oxidoreductases↗
Metabolism of sphingosine bases. X. Degradation of (1-14C)dihydrosphingosine (Sphinganine), (1-14C)2-Amino-1,3-dihydroxyheptane and (1-14C)dihydrosphingosine phosphate in rat liver.
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Amino Alcohols↗
Distribution and properties of dihydrosphingosine-1-phosphate aldolase (sphinganine-1-phosphate alkanal-lyase).
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Aldehyde-Lyases↗
Monolayer studies with synthetic saturated, mono- and polyunsaturated mixed 1,2-diglycerides, 1,2-diacylphosphatidylethanolamines and phosphatidylcholines at the air-water-interface.
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Arachidonic Acids↗
[Metabolism of sphingosine bases. XII. Eicosasphinganine (eicosadihydrosphingosine) and 3-dehydroeicosasphinganine (3-dehydroeicosadihydrosphingosine)].
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Amino Alcohols↗
The relationship between phospholipid biosynthesis, spingosine degradation and serine metabolism.
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Amino Alcohols↗
Studies on the occurrence and properties of lysosomal phospholipases A1 and A2 and the degradation of phosphatidic acid in rat liver lysosomes.
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Animals↗
[Hydrolysis of complex lipids by lysosomal enzymes from rat liver].
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Chemical Phenomena↗
[Relation of sphingosine degradation and serine metabolism to the biosynthesis of phospholipids].
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Amino Alcohols↗
[On the fine structure of membranes of animal cells].
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Animals↗