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Biomedical subjects

W Steinbach

Publications and source records attributed to W Steinbach.

11 recordsLinked to original sources

[Effectiveness of various forms of therapy in chronic cardiovascular diseases--a vector analysis of the transition probabilities of degrees of severity].

The present findings result from a check of probationers representative for approx. 280,000 inhabitants of defined territories, who had been designated as suspects of heart and vessel disease on grounds of X-ray-morphological criterions (classification by Richter). Those about 3,000 suspects, subdivided into 3 comparable patient groups A, B and C, underwent different regimes of treatment of outpatient medical practice after standardized and noninvasive diagnostics in a follow-up during 5 years and had been valued by means of a problem-specific grading. The comparative analysis about the distribution of severe degrees concerning hypertension and coronary heart disease after the conclusion of the intervention showed significant differences concerning the results of treatment to the credit of the patient group A (treated by specialists) contrary to the patient group B (treated by family doctors) and patient group C (principle of announcing the patients themselves). Also the patient group B showed significantly better results of therapy compared with the patient group C. In addition to the concluding rating the estimation of yearly transition of severe degrees gave an insight into the therapeutical decision of the person who looks after as well as the different distribution of severe degrees of special heart diseases in dependence on the starting severe degree in the special period of intervention conditioned on the therapy. The results gain exceptional importance for practice on the grounds of methodics of the study-automatable classification of dv-thorax-X-ray pictures, problem-specific grading of noninvasive, simple parameters, variants of therapy in dependence on the graduated system of medical care.

Coronary Disease

[Random sample size in ROC analyses].

ROC analysis has proved useful in assessing diagnostic efficiency. Large x-ray film series of thoracic images intended for cardiovascular diagnosis were used for studying diagnostic efficiency in relation to random sample size. Exploration of random samples from two classes of findings requiring diagnostic differentiation, with the same number of x-ray films in each class, showed satisfactory convergence between the radiologists' rating and the ROC curve if the size of the random sample groups was about 200 images each or larger. The smaller the random sample size (less than 200 images), the greater the scatter of the rating performance. In another series the rating ability of experienced radiologists was compared with that of a semi-automatic classificator. The semi-automatic classificator attained almost the same performance index as the low-performance evaluator.

Decision Theory

Image quality of an image-intensifier fluorographic system.

For an image-intensifier fluorographic system, all essential image-quality parameters (such as MTF, noise Wiener spectrum, sensitivity, and characteristic curve) were determined. The results are in good agreement with theoretical considerations and allow a specification of the influence of the system's components on image quality. Film noise especially, because of the small image format, is of much more importance than had been assumed. A formula for the adjustment of system sensitivity (optimum input dose) has also been derived.

Fluoroscopy

[Explanations for the standard in roentgen diagnosis: basic tests of the thoracic organs--adults].

Explanations are given concerning the standard of radiodiagnostics--basis examination of the organs of the thorax/TGL-No. 36661, which shall facilitate the understanding of the parameters given. It results from the fact that the roentgenological examination of the organs of the thorax begins with a posterior-anterior ray-path radiograph of the thorax. In these cases the large format technique with film-foil-combination and the fluorography are classified as equivalent. With regard to the high speed of movement to be expected is striven for the achievement of possibly short times of exposure. The authors briefly enter the particularities of the radiograph of the thorax in lateral as well as in the full size radiograph sitting and lying positions and at the patients bed. Due to the law solution and the higher radiation dose the fluoroscopy is to be used only with regard to the findings and other information concerning the patient.

Diaphragm

[Light and electron microscope study of the cerebellar cortex in the cow, sheep and goat].

In order to investigate the fine structure of the cerebellar cortex of domestic ruminants, tissue specimen were taken of the Lingula, Declive, Nodulus, Lobus paramedianus and Flocculus of 30 cows, sheep, and goats. The following techniques were used: Luxol-Fast-Blue and Nisslstaining, Bodian and Golgi impregnation according to BUBENAITE and to KEMALI (1976). Electronenmicroscopically, differences between these species were seen only in the thickness of the three layers and in the size and topography of the 7 different cells and the fibres of the cerebellar cortex. In contrast to other species, soma and fibres of the Purkinjecells often contained numerous lamellar bodies. As in other animals the granular endoplasmic reticulum is arranged in form of nuclear caps.

Animals