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Biomedical subjects

W Stanford

Publications and source records attributed to W Stanford.

At least 127 records · Page 7Linked to original sources
PubMed1977

Bronchial carcinoid tumors in children and adolescents.

Thirteen histologically proven cases of bronchial carcinoid from the literature and eight cases from the Armed Forces Tumor Registry, all under 20 yr of age, are presented. Hemoptysis, cough, and pneumonia were the most frequent presenting complaints. Bronchoscopy defined the lesion in all 16 cases so studied. Gross and microscopic pathology is briefly described, and treatment in these cases outlined. A good long-term prognosis can be expected, except in those cases with a long delay in diagnosis.

Adolescent↗
PubMed1977

Thromboembolic phenomena in patients with prosthetic aortic valves who did not receive anticoagulants.

Seventy-two patients with Starr-Edwards aortic prostheses of the 2300 series were followed for 1 to 73 months (average, 22 months) without receiving anticoagulants. Nine patients had clinical evidence of an embolic episode (12.5%). One of these patients died, and 5 were left with a significant residual neurological deficit. Two other patients had hemiparesis but recovered fully. Only 1 episode could be considered minor. The reported lower incidence of thromboembolism in patients receiving this prosthesis with adequate anticoagulation has now led us to reverse our previous position and recommend anticoagulation for patients receiving Starr-Edwards aortic prostheses.

Adult↗
PubMed1976

Results of treatment of primary carcinoma of the lung. Analysis of 3,000 cases.

Three thousand patients with primary carcinoma of the lung entered in the Armed Forces Central Medical Registry are reported. Forty-one per cent had squamous cell, 28.5 per cent adenocarcinoma, 25.2 per cent small cell/undifferentiated, and 4.9 per cent miscellaneous cell types. When first seen, 71.1 per cent had no organ metastases and 50.6 per cent no lymph node metastases. Over-all survival rate was 18.2 per cent at 5 years and 14.5 per cent at 10 years. Survival following definitive resection, palliative resection, definitive radiation, palliative radiation, and chemotherapy was determined both in the presence of mediastinal nodal involvement and in the absence of mediatinal nodal involvement. Where resection for cure could be carried out, 5 year survival rates of 48.8 per cent were possible. The factors affecting this improved outlook in our military population are discussed and, in general, appear to be related to a ready accessibility of medical care and the necessity, because of global commitments, of establishing an early diagnosis. Cell type ecerted some influence on survival, but the major determinant appeared to be the absence of involved nodes at the time of the operation.

Adenocarcinoma↗
PubMed1976

Human skin burns induced by defibrillator default current.

The attachment of various types of electronic instrumentation to a patient can lead to hazardous interactions. Component malfunction in a single piece of equipment connected to a patient may be totally innocuous. However, the same fault occurring in an identical piece of equipment functioning as one component in a network of monitoring and electrosurgical equipment can result in severe burns or even electrocution. This paper describes interaction between a defective defibrillator paddle and an electrosurgical unit. Burns and ventricular fibrillation resulting from this malfunction and interaction are described in detail and the electrical circuits are analyzed.

Burns, Electric↗
PubMed1976

Doppler ultrasonic flow detection as an adjunct in the diagnosis of patent ductus arteriosus in premature infants.

Since ligation of a patent ductus arteriosus in the neonate with idiopathic respiratory distress syndrome seems to improve the clinical condition of the infant, we have attempted to identify those neonates earlier with the noninvasive Doppler ultrasonic technique, recording brachial arterial flow signals. Sixteen patients were studied. In the 5 with reversed brachial flow who were operated upon, ligation of a PDA resulted in improvement and postoperative correction of brachial flow reversal as evidenced by the Doppler ultrasonic technique.

Doppler Effect↗
PubMed1975

Mediastinoscopy. Its application in central versus peripheral thoracic lesions.

In an attempt to ascertain the value of mediastinoscopy in peripheral lung lesions, records of 157 patients undergoing cervicomediastinal exploration (CME) at Wilford Hall USAF Medical Center were reviewed. Among patients with benign lesions, CME was positive in 90.6% of those who had central lesions and 58.3% of those with peripheral lesions. It was positive in all 7 patients who had peripheral lesions with associated mediastinal nodes on roentgenogram and negative in all 5 who had peripheral lesions without nodes. In the patients with malignant lesions, CME was positive in 72.9% of those who had central lesions and 58.1% of those with peripheral lesions. It was positive in 24 of 27 patients who had peripheral lesions with associated mediastinal nodes and negative in 15 of 16 patients with peripheral lesions without nodes. Although we recognize this to be a selected series, CME does appear to be valuable in patients with central lesions and peripheral lesions with mediastinal nodal involvement on roentgenogram. It does not appear to be as useful in those with peripheral lesions who do not have central nodal involvement.

Adenocarcinoma↗
PubMed1975

Coronary bypass surgery. Value of maximal exercise testing in assessment of results.

To evaluate the relationship of results of maximal treadmill testing and results of saphenous vein bypass surgery (SVG), 30 patients underwent a maximal treadmill test before and after SVG; an additional 39 had results of postoperative exercise testing available. These patients were part of a group of 91 patients (95% of 96 survivors) who had complete right- and left-heart catheterizations and coronary angiography before and after operation. Twenty-one per cent had improved ejection fractions postoperatively; in 32% ejection fractions were worse. Duration of maximal treadmill exercise correlated poorly with ejection fraction changes or graft patency. Rate-pressure product (RPP) was usually lower postoperatively in patients with worse ejection fractions, primarily because of a low systolic blood pressure at maximum exercise. RPP postoperatively of less than 25,000 almost always meant poor surgical results, either graft occlusion or poor left ventricular function, while RPP of more than 30,000 meant that left ventricular function was preserved and all grafts or the graft to the anterior descending were patent. Thus, success or failure of SVG in these groups may be predicted without postoperative catheterization. An open graft to the anterior descending coronary generally insured a high RPP with exercise, even if other grafts were closed, as long as ventricular function remained good.

Angina Pectoris↗
PubMed1975

Dissimilar metals in a rib spreader a surgical electrical hazard.

A case is presented and electrochemical theory is discussed in a situation in which a battery was produced between two dissimilar metals in a Finochietto rib spreader. The problem developed in the thorax of a patient undergoing transthoracic cervical sympathectomy and resection of the first rib. Caution is advised in the use of dissimilar metals in patients undergoing surgery.

Adult↗