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Biomedical subjects

W Schumann

Publications and source records attributed to W Schumann.

81 records · Page 5Linked to original sources

Bacteriophage-specific DNA-binding proteins in P22-lysogenic and in P22-infected Salmonella typhimurium.

Crude extracts of Salmonella typhimurium lysogenic for phages P22 or L contain proteins that specifically retain phage DNA on nitrocellulose filters. Three DNA-binding activities were found after infection with P22. One is P22 specific, accounts for the largest proportion of DNA-binding proteins, and corresponds most likely to the c2 repressor. An early transient binding activity measured with both P22 and L DNA was found to be directly related to the expression of genes c1 and c3. A third, late binding activity for P22 and L DNA is related to phage production.

DNA, Viral↗

The bacteriophage Mu gene B product is incorporated into the inner membrane of Escherichia coli.

By using the Triton X-114 method, it could be shown that an Mr 33 000 protein expressed from the left-end EcoRI-C fragment of phage Mu behaves like a hydrophobic protein. Fusion of a DNA region coding for this protein to the controllable pL promoter of phage lambda results in the production of large amounts of the 33-kDal protein under inducing conditions. This protein can be isolated in association with the inner membrane of Escherichia coli cells. Based on complementation studies it was concluded that the 33-kDal protein is the product of the early gene B.

Bacterial Outer Membrane Proteins↗

[Differential diagnosis of vital and postmortem processes in burn cadavers].

After presenting the most important intravitam reactions in 114 burnt corpses of the Göttingen autopsy material covering the years 1969-83 two cases are described with a) a so called burn haemorrhage in the stomach b) an extremely wide spreading of the upper thighs. Differential diagnosis and forensic significance of these findings according to chemical, histopathological and experimental examinations are discussed.

Animals↗