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Biomedical subjects

W Schreiber

Publications and source records attributed to W Schreiber.

At least 109 records · Page 6Linked to original sources
PubMed1984

TMAO-ase activity in tissues of fish species from the Northeast Atlantic.

The influence of various parameters (evacuation; pH value; addition of Fe2+, cysteine, ascorbic acid and methylene blue) on the activity of the trimethylamine oxide demethylase (TMAO-ase) in extracts from the kidney of saithe (Pollachius virens L.) is described. Assay conditions resulting in maximum formaldehyde (FA) production were used to measure the TMAO-ase activity in kidney, spleen, liver, pyloric caeca, blood and muscle from Northern Atlantic fish species. Only in organs from fishes of the order Gadiformes could TMAO-ase activity be detected. The TMAO-ase was most active in kidney and spleen whereas in muscle the enzyme activity could be barely detected.

Animals↗
PubMed1984

[Comparative study of atracurium and alcuronium for the intubation of older patients in halothane anesthesia].

Intubation conditions, onset time (time from the end of the injection until the maximum twitch depression (1 Hz) of the adductor pollicis muscle) as well as changes in blood pressure and pulse rate were studied in a randomized double-blind study of 40 male patients (average age 69-70 years) anaesthetized with halothane following atracurium (ATR) 0.33 mg X kg-1 or alcuronium (DAN) 0.1 mg X kg-1. An additional group received succinylcholine (SCH) 1.0 mg X kg-1. Intubation conditions at the end of the onset time were slightly and significantly better after ATR than following DAN, in each case, however, distinctly worse than after SCH. The onset time amounted to 115.0 s after ATR and 125.0 s following DAN (48.6 s after SCH). Neither ATR nor DAN showed statistically significant effects on blood pressure or pulse. One bronchospastic reaction which responded to therapy was observed per group. ATR proved to be comparable to DAN in respect to effectiveness and safety.

Aged↗
PubMed1984

[Massive intracerebral hemorrhage and anterior spinal artery syndrome in etiologic relation to paraspinal anesthesia procedures? 2 case reports].

Complications in connection with operations also lead to the question of possible relations to the type of anaesthesia and their avoidability. The subject is treated demonstrating two cases of intracerebral haemorrhage and anterior spinal artery syndrome during and following catheter-epidural anaesthesia or spinal anaesthesia, respectively. No definite causal connection was established, even if the emergencies presumably would not have occurred without operation and anaesthesia. Complications are not completely avoidable, even if operation and anaesthesia as regards indication, execution and monitoring, are carried out correctly.

Adult↗
PubMed1981

[Think of malaria!].

A drug addict, treated because of a lung abscess, was found to have plasmodium vivax malaria and was treated accordingly. The second patient acquired falciparum malaria inspite of chloroquine prophylaxis and was admitted with a thrombocytopenia of 24 000 mm3. After chloroquine treatment the platelet count became normal. Thrombocytopenia is usually present in falciparum malaria. Complications and their treatment are discussed.

Adult↗
PubMed1981

[Multiphasic neuromuscular blockade during and following regional application of succinylcholine in man (author's transl)].

The influence of the isolated arm technique on the development of the neuromuscular block induced by succinylcholine (suxamethonium) was investigated in 11 anesthetized patients using the adductor pollicis twitch method. A multiphasic course was shown: phase A (=occlusionphase) during ischemia; phases B1 and B2 (=post occlusion phases) after restoring circulation. The mean maximal depression of control twitch height increased from 60.4% in phase A to 75.2% in phase B1 and on up to 96.4% in phase B2. The mean onset time from releasing the tourniquet to first depression of twitch height amounted to 4.9 s in phase B1 and 27.8 s in phase B2. The multiphasic course is interpretated as the consequence of a temporary disequilibrium of muscle perfusion with the regional method. A neuromuscular effect after opening the tourniquet was evident in 3 out of 8 simultaneous studies on the control arm. An abnormal myotonic reaction was observed repeatedly in 1 patient.U

Adult↗