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Biomedical subjects

W Schoop

Publications and source records attributed to W Schoop.

At least 37 records · Page 2Linked to original sources
PubMed1985

[Significance of the ejection fraction at rest and by stress using radionuclide ventriculography for the prognosis of myocardial infarct patients--comparison with other study methods].

We examined 221 patients with postmyocardial infarctions 8 weeks after MI using radionuclide ventriculography (RNVA) at rest (EFR) and during supine submaximal exercise (delta EF). Mortality rates were evaluated 2 1/2 and 3 1/2 years later by interviewing patients and/or their homephysicians. Sixteen patients were dead (6.7%) 2 1/2 years after MI, 28 (12.7%) were dead after 3 1/2 years. Thirty percent of patients with a resting EF less than 30% had died 2 1/2 years after MI, and 40% were dead within 3 1/2 years. The mortality rate was significantly higher than in patients who had EF greater than or equal to 30% 8 weeks after MI. Patients with a decrease of delta EF (greater than or equal to 5%) showed a 2 1/2 year mortality of 10.8% and after 3 1/2 years of 18.5%. Mortality was significantly higher in patients with decreasing EF during exercise than in those who increased their EF during exercise. This prognostic value of EFR and delta EF was compared with other parameters (angina pectoris, ECG at rest and during exercise, heart volume, Holter ECG, floating catheter PCP [rest and exercise], coronary angiography). Radionuclide ventriculography at rest and during exercise showed a tendency to be the best determining factor for prognosis, and is therefore recommended to determine prognosis in post-MI patients.

Adult↗
PubMed1984

Clinical significance of Doppler velocity and blood pressure measurements in peripheral arterial occlusive disease.

In 20 normals and 50 limbs with arterial occlusive disease, Doppler flow velocity and blood pressure in different levels of the leg were determined at rest and during reactive hyperemia. While blood pressure measurement at the ankle and flow velocity analysis at the posterior tibial artery were of use in the diagnosis of arterial occlusion, recording the mean femoral flow velocity during reactive hyperemia showed less diagnostic value. Ankle blood pressure was determined after two different exercises--knee exercise and ankle exercise. A greater decrease of blood pressure was observed after ankle exercise than after knee exercise in limbs with isolated occlusion of the femoral artery, and a less decrease in limbs with isolated occlusion of the iliac artery. These findings indicate that comparison of ankle blood pressure after two exercises is useful as a screening test to detect the combined ilio-femoral diseases.

Angiography↗
PubMed1983

Results of percutaneous transluminal angioplasty.

Percutaneous transluminal angioplasty (Dotter technique) was used in 2,942 cases of iliofemoral atheromatous disease. Results varied with the characteristics of the obstructing lesion (length and location) and the clinical stage of ischemia (claudication, rest pain, gangrene). Based on the foregoing, angioplasty is done either as the preferred primary treatment or for the relief of clinically advanced disease in patients unsuitable for high risk surgery. Success is favored by the use of aggregation inhibitors and single-use Teflon or balloon catheters; complications are few.

Aged↗
PubMed1981

[Intravenous fibrinolytic treatment in chronic ischemic heart disease (author's transl)].

In 13 male patients (mean age 49.1 years) with chronic ischemic coronary heart disease (7 transmural and 2 intramural myocardial infarctions), angina pectoris and signs of ischemia during exercise an intravenous streptokinase therapy was performed. The treatment was installed 18.9 months after infarction or after onset of angina pectoris. Before and after intravenous streptokinase therapy the following parameters were measured: history, heart volume, exercise-ECG, Swan-Ganz pulmonary artery measurements during exercise, aortic and left ventricular pressures, coronary angiography, left ventricular angiography. 1. Angina pectoris disappeared in 1 and became better in 4 patients. In none of the patients angina pectoris became worse. 2. The parameters for ischemia were not changed overall by the therapy. But in single patients signs of exercise-induced ischemia were influenced. 3. Mean values of left ventricular function (EF, LVEDP) were not changed. 4. Angiographic changes were discrete. 5. Complications of therapy and worsening of subjective parameters did not occur. 6. The angina pectoris behaviour in 5 patients (became better) is explained by changes of blood properties. The not-appearance of coronary artery occlusions is explained by the inhibition of platelet aggregation. 7. It is suggested that the effect of intravenous streptokinase therapy should be examined in patients with short-lasting angina pectoris and subgroups, such as initial angina pectoris.

Adult↗
PubMed1981

Normovolemic hemodilution in peripheral arterial disease.

In 25 patients with arterial occlusive disease in clinical stage IV (Fontaine) a normovolemic hemodilution to an average hematocrit of 0.31 +/- 0.02 was performed. Eighteen patients had peripheral ulcers of the lower limbs and three had ulcers of the upper limbs. Four patients had lesions of both hands and feet. The average age of the patients was 43. Hemodilution was achieved by repeated withdrawals of approximately 500 ml of blood, followed by reinfusion of the autologous plasma and infusion of low-molecular weight dextran solution to avoid hypovolemia. In all patients with peripheral ulcers of the upper limbs, a good to a very good clinical effect was obtained. The healing tendency of lesions on the feet and toes were less marked and depended basically on the total number of vascular impediments. The rheological and hemodynamic basis of the therapeutic effect of hemodilution and the preliminary criteria for indicating this therapy are discussed.

Adult↗