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Biomedical subjects

W S Ho

Publications and source records attributed to W S Ho.

43 records · Page 3Linked to original sources

Paraffinomas of the breast: mammographic, ultrasonographic and radiographic appearances with clinical and histopathological correlation.

Paraffinomas are uncommon lesions occasionally encountered in the breast. The clinical and radiological (mammographic, ultrasound and plain film) features are presented in five patients with breast paraffinomas, one of whom had synchronous infiltrative ductal carcinoma. Histopathological correlation was available in two patients. Women with a history of paraffin injections into the breast may present decades later with hard, nodular breast masses simulating breast cancer. Dense fibrosis particularly in the retroglandular midbreast region causing streaky opacities and bizarre architectural distortion on mammography suggests the diagnosis. Flocculent, amorphous, ring or rounded calcifications may also be present within the breast and axilla. Migration of liquid paraffin through the tissue planes can result in diffuse conglomerate calcification in the chest and abdominal walls.

Aged↗

[Destructive paraffinoma of the breast and thoracic wall caused by paraffin injection for mammary increase. Apropos of 3 cases with review of the literature].

The injection of a high viscosity fluids into the tissues for cosmetic body contouring has been practised in the last four decades in the East and South-East of Asia. The injection of liquid paraffin for mammary augmentation was widely practised by surgeons, physician and even non medical people. Unfortunately, most of these cases ended by having different varieties of paraffinoma as a complication of a foreign body reaction. We report three cases of a destructive form of these paraffinomas ulcerating into both breasts and the anterior chest wall. One case was treated by bilateral mastectomy, radical excision of the anterior chest wall soft tissue and reconstruction by a vertical Rectus Abdominus Myocutaneous Flap. The second case had bilateral mastectomy and followed up for facial paraffinomas. The third case was just followed for up regular wound care as surgery was not indicated due to advanced age, poor general condition and the family request.

Aged↗

Model pores of molecular dimension. The preparation and characterization of track-etched membranes.

Extremely uniform pores of near molecular dimension can be formed by the irradiation-etching technique first demonstrated by Price and Walker. The technique has now been developed to the stage where it can be used to fabricate model membranes for examining the various steric, hydrodynamic, and electrodynamic phenomena encountered in transport through molecular-size pores. Methods for preparing and characterizing membranes with pores as small as 25 A (radius) are described in this paper. Results on pore size determination via Knudsen gas flow and electrolyte conduction are compared. Pore wall modification by monolayer deposition is also discussed.

Biological Transport↗

Boiling wax burn in mid-autumn festival in Hong Kong.

An unusual cause of burn, contact with boiling wax by children and adolescents during the annual mid-autumn festival in Hong Kong is presented. 57 patients who suffered from hot wax burn over the period 1986-1996 were admitted to the Burns Unit of the Prince of Wales Hospital. This special burn should be preventable by public education.

Adolescent↗

An analysis of 550 hospitalized pediatric burn patients in Hong Kong.

A total of 550 acute burn patients under the age of 15 years were admitted to the Burns Unit of Prince of Wales Hospital, Hong Kong between March 1993 and February 1999. There were 337 males and 213 females with a male to female ratio of 1.58:1. The median age was 2.5 years and the median burn size was 5% total body surface area (TBSA). Toddlers of age < 2 years accounted for 235 (42.7%) of admission. Domestic burns resulted in 481 (87.5%) injuries followed by play-related burns that caused 34 (6.2%) admissions. Scalding was the most common cause of injury, which accounted for 497 (90.4%) admissions, followed by flame burns, which resulted in 45 (8.2%) injuries. Nine patients (1.6%) had inhalation injury requiring intubation and ventilatory support. The median hospital stay was 8 days and there was no seasonal variation in admission. The majority of patients (80.2%) had their wounds healed without any operation. Only 19 out of 550 patients (3.5%) had burns of 30% TBSA or larger, and only nine patients (1.9%) had inhalation injuries. Only one patient died in this series, which yielded a mortality rate of 0.2%.

Adolescent↗

Amoxycillin and clavulanic acid versus cefotaxime and metronidazole as antibiotic prophylaxis in elective colorectal resectional surgery.

In a prospective randomised controlled trial, amoxycillin plus clavulanic acid was compared to a combination of cefotaxime and metronidazole as prophylactic antibiotics in 164 patients who underwent elective colorectal resectional surgery. Wound infection occurred in 15 patients (9.1%) and deep surgical infection in 4 (2.4%). Seven cases of wound infection and 2 cases of deep infection occurred in the amoxycillin plus clavulanic acid arm, while 8 cases of wound infection and 2 cases of deep infection occurred in the cefotaxime plus metronidazole arm. Eighty-eight percent of infections occurred in patients who had low anterior resection or abdominoperineal resection of the rectum. Both the amoxycillin plus clavulanic acid and the combination of cefotaxime and metronidazole offer the same degree of protection against post-operative infection. The use of amoxycillin plus clavulanic acid as antibiotic prophylaxis is recommended because of its easier use and cheaper cost.

Adult↗