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Biomedical subjects

W Rudolph

Publications and source records attributed to W Rudolph.

At least 109 records · Page 6Linked to original sources
PubMed1981

Exercise testing in patients with valve replacement.

To determine whether detection of pathologic exercise hemodynamics can be based on assessment of noninvasive parameters, pulmonary artery pressure and cardiac output were measured during graded bicycle ergometry in 33 patients with mitral valve replacement and 42 patients with aortic valve replacement. No relationship could be established between exercise capacity, achievement of steady-state conditions of blood pressure and heart rate, the extent of heart rate increase and incurrence or extent of pathologic exercise hemodynamics. Thus, the results show that accurate evaluation of cardiovascular status during exercise in patients with valve replacement cannot be obtained without direct determination of the pressure-flow relationship.

Aortic Valve↗
PubMed1981

A simple method in investigating anti-human lymphocyte globulin.

The methods involves the influence of AHLG on the electrophoretic mobility of platelets and lymphocytes. There is a close correlation between the electrophoretic inhibitory effect of AHLG on platelets and the thrombocytopenic AHLG effect in vivo, so that method can be used for evaluating the unwanted AHLG side-effects on platelets.

Antilymphocyte Serum↗
PubMed1980

Serial electrocardiographic changes during long-term treatment of severe hypertension with minoxidil.

The effects of minoxidil on the electrocardiogram (EKG) were assessed in a prospective investigation of 112 patients with severe hypertension during an observation period representing 241.5 patient-years. Highly significant blood pressure reductions at rest and during exercise were achieved and maintained with the combination of minoxidil, beta-adrenergic blocking agents, and diuretics. In 90% of the patients, the initiation of minoxidil was associated with nonspecific T-wave changes in the EKG consisting of flattening or inversion, which ranged from slight to very marked. While these changes may initially appear disconcerting, the observations of this study show that they are not related to changes in heart rate or other clinical criteria associated with myocardial ischemia. The changes remain unaltered during the tachycardia of exercise, they are not influenced by beta-adrenergic blockage, and they generally revert to their control appearance during chronic treatment. During long-term treatment, a substantial reduction of the increased QRS voltages occurred.

Adolescent↗