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Biomedical subjects

W Rossmanith

Publications and source records attributed to W Rossmanith.

39 records · Page 3Linked to original sources

beta-1-Glycoprotein determination in normal and disturbed pregnancy.

beta-1-Glycoprotein (SP1) concentration of 170 women with undisturbed pregnancy under 18th week were taken as reference. SP1 levels of 72 patients with threatening abortion but favorable outcome were compared with those of 70 patients with threatening abortion and subsequent miscarriage. Decreased SP1 levels were determined in most (88%) patients who aborted, whereas 88.8% of patients with favorable outcome had SP1 levels within normal range. The predictive value of SP1 determination in early pregnancies is emphasized.

Abortion, Threatened↗

Studies on the neurotransmitter binding to pig brain microvessels.

Microvessels from pig brain areas were prepared by differential centrifugation techniques. These fractions were assayed for purity and structural unity by marker enzyme determination, light and electron microscopy. Binding properties of 3H-flunitrazepam were studied in different brain regions. Kinetic studies of 3H-flunitrazepam showed BMax-values of 0,42 +/- 0,3 pmol/mg protein and KD-values of 1,26 +/- 0,6 nM and were compared to a synaptosomal membrane fraction (P2-fraction) with BMax = 2,68 +/- 0,5 pmol/mg protein and a KD of 1,95 +/- 0,3 nM. GABA kinetic studies gave IC50-values of 250 nM in the microvessel fraction and 40 nM in the P2-fraction.

Animals↗