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Biomedical subjects

W Rokicki

Publications and source records attributed to W Rokicki.

At least 109 records · Page 6Linked to original sources

Circulatory system in children with localized scleroderma.

The circulatory system was studied in 43 children (ages 3-18 years, mean 10.6 years; 32 girls, 11 boys) suffering from localized cutaneous forms of scleroderma. The following studies were undertaken: general pediatric examination, cardiologic examination including routine electrocardiogram (ECG), 24-h Holter ECG monitoring, echocardiography plus Doppler study, and a treadmill exercise test. Three children found to have congenital heart malformations were excluded from the study. Children with localized scleroderma were often lighter and shorter than their appropriate controls. The most common ECG abnormality was incomplete right bundle branch block, but other ECG and Holter abnormalities were found as well. Abnormal echocardiographic results were obtained in 16 cases. The abnormalities concerned valvar function (in all heart valves but predominantly in the mitral valve). It was found that the children suffering from scleroderma had different indices than controls for left ventricular mass index, mitral valve function and left ventricular filling. During the exercise test (conducted according to Bruce's protocol) we found no difference between patients and controls.

Adolescent↗

[Dioxins].

Explore the source record for details and available documents.

Abnormalities, Drug-Induced↗

[Evaluation of the usefulness of analysis of beta-glucuronidase levels in patients with superficial cancer and papilloma of the bladder].

Beta-glucuronidase activity in the blood serum, the urine, and tumour tissue has been assayed in patients with superficial bladder neoplasm and papilloma of the bladder prior to and after transurethral electroresection (TUR). Twenty five healthy subjects constituted a control group. It was shown that the activity of beta-glucuronidase may be a valuable test in the differential diagnosis of bladder neoplastic lesions as well as in the assessment of the results of therapy with transurethral electroresection.

Adult↗

Effect of long term insulin infusion into rat portal vein on regenerating liver.

The effect of long term intraportal infusion of insulin on liver regeneration has been studied in rats 24, 36 and 48 hrs after partial hepatectomy. Our studies showed an enhancement by insulin of some parameters of rat liver regeneration, i.e. a rapid increase of the DNA and RNA levels as well as the TTK activity in the whole liver homogenate and all the subcellular fractions examined. The influence of insulin was marked during the whole time of experiment, but the most significant changes occur during the first 24 hrs after partial hepatectomy.

Animals↗