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Biomedical subjects

W R Miller

Publications and source records attributed to W R Miller.

At least 325 records · Page 18Linked to original sources
PubMed1976

Psychiatric disturbances of aged patients in skilled nursing homes.

The authors found that 85% of 74 patients supported by Medicaid in two skilled nursing facilities had significant psychiatric disorders in addition to serious multiple medical illnesses. Almost two-thirds of the psychiatric disturbances had not been diagnosed. Although staff were more concerned with the psychosocial than the physical aspects of patients' problems in more than half of the cases, they often had difficulty recognizing the legitimacy of psychological complaints and relating to patients with psychological disturbances. Staff were not clear about the orders for psychotropic medications that were prescribed for more than half of the patients. The authors point out that more psychiatric consultation is needed to ensure appropriate and effective care for psychiatric patients in such facilities.

Aged↗
PubMed1976

External peer review of skilled nursing care in Minnesota.

External peer review of each of the 8917 Medicaid patients in 228 Skilled Nursing Facilities in Minnesota demonstrated characteristics and needs of patients and produced documented recommendations for Medical Evaluation Studies to strengthen multiple aspects of treatment programs. As a whole, Medicaid patients were well placed and well cared for. However, wide variations were observed in individual facilities. Principal problem areas were those which prevail in all long term care facilities in this country: weakness of individualized treatment, weakness of restorative goal-oriented treatment, severe mental/emotional/behavioral disabilities, lack of strong leadership in medical and nursing professions, and weakness of psychosocial support programs.

Activities of Daily Living↗
PubMed1976

Hyperprolactinemia and steroid metabolism by rat mammary adenocarcinomas.

The metabolism of both testosterone and dehydroepiandrosterone by 10 adenocarcinomas induced and grown in the presence of high prolactin (plasma prolactin greater than 220 ng/ml) was compared with the metabolism of 10 adenocarcinomas induced and grown in the presence of normal levels (plasma prolactin less than 60 ng/ml). The tumors associated with high prolactin significantly metabolized more testosterone to both 5alpha-dihydrotestosterone and 5alpha-androstanediol. The metabolism of dehydroepiandrosterone was similar in both groups of tumors. It is concluded that prolactin may differentially influence the metabolism of C19 steroids by rat mammary adenocarcinomas.

Adenocarcinoma↗
PubMed1975

Urinary aetiocholanolone in patients with early breast cancer from South East Scotland and South Wales.

Urinary aetiocholanolone levels have been measured in 417 women aged between 20 and 70 years. The women were drawn from South East Scotland and South Wales and consisted of patients with either benign or malignant disease of the breast and control patients suffering from no detectable breast disorder. The pattern of aetiocholanolone excretion with respect to age and menopausal status has been defined in each group of patients. No significant differences in urinary levels have been detected between patients with breast disease, whether benign or malignant, and control patients. More detailed examination of the 201 women with early cancer of the breast has also shown that there is no consistent correlation between pre-operative aetiocholanolone levels and factors of prognostic significance detectable at the time of primary treatment-tumour size, grade, round cell infiltration, histological involvement of nodes by tumour and the clinical palpability of lymph nodes. It would seem, therefore, that the prognostic value of pre-operative aetiocholanolone measurements is somewhat limited in patients with early breast cancer. It is noted, however, that low levels of aetiocholanolone are associated with post-menopausal patients, a group in which the prognosis is generally poorer than that in pre-menopausal women.

Adenofibroma↗
PubMed1975

Learned helplessness, depression, and anxiety.

The learned helplessness model of depression predicts that depressives should tend to perceive reinforcement as response-independent in skill tasks. Depressed-anxious, nondepressed-anxious, and nondepressed-nonanxious college students estimated their chances for success in a skill or a chance task. (Virtually no depressed-nonanxious subjects could be obtained.) Depressed-anxious subjects showed less expectancy change in skill than nondepressed-anxious subjects, while these two groups exhibited similar expectancy change in chance. Nondepressed-anxious and nondepressed-nonanxious subjects did not differ in either skill or chance. The results for a discrimination learning problem were mixed. The groups did not differ in latency to shut off an aversive noise. So, depressed subjects perceptually distort the outcomes of skilled responding as being response-independent, and they may, under certain conditions, show deficits at learning the consequences of responses. These deficits may reflect learned helplessness and are specific to depression.

Anxiety↗