Biomedical subjects
W R Hudson
Publications and source records attributed to W R Hudson.
Exostosis of the mandibular coronoid process.
Abnormal enlargement of one or both mandibular coronoid processes may lead to a limited mandibular excursion. A case of unilateral coronoid process exostosis severely limiting mandibular function is described. A review of the literature pertinent to this uncommon abnormality is presented. The various entities of coronoid process osteochondroma, osteoma, exostosis, hypertrophy and developmental anomaly, all producing a similar picture of coronoid process enlargement are discussed. The proper use of the available radiographic techniques simplifies the diagnosis of these uncommon maladies, as long as a coronoid process abnormality is considered in the differential diagnosis of restricted mandibular movement.
Treatment of radiation-induced tissue injury by hyperbaric oxygen.
Hyperbaric oxygen therapy appears to be a beneficial adjunctive treatment modality in the management of radionecrosis of bone and soft tissue in the head and neck. The mechanism of such wound healing enhancement appears to be related to oxygen stimulation of fibroblastic activity and neovasculation. In this pilot study, involving 13 cases of refractory mandibular radionecrosis treated with hyperbaric oxygen, complete healing of soft tissue disease with covering of exposed bone has been noted in seven cases 11 to 27 months posttreatment; transient healing was seen in three cases; moderate to marked improvement in soft tissue disease has been noted in three cases. Pain relief was marked in six cases, moderate in four cases, and slight in one case of the 11 patients with significant pretreatment pain. Radiographic improvement was slight to moderate in ten cases. Four of the five patients with pathologic fractures developed a firm fibrous union of the mandibular segments during or shortly after treatment. Three additional cases of head and neck radionecrosis of other sites have noted significant improvement in their lesions during treatment. Three other patients with radionecrosis of the foot, hip, and vagina have also been treated with good results only in the vaginal case. None of the 19 patients treated with hyperbaric oxygen developed persistent or significant complications.
Hyperbaric oxygen therapy for laryngeal radionecrosis.
Radionecrosis of the larynx is a debilitating disease associated with pain, dysphagia, respiratory obstruction, and, in some cases, the need for laryngectomy. Persistent poor wound healing can lead to death. A series of eight patients with advanced (grades III and IV, Chandler classification) radionecrosis of the larynx treated with adjunctive hyperbaric oxygen therapy is presented. Signs and symptoms of radionecrosis were dramatically ameliorated in seven of eight patients, while one patient, despite subjective improvement, eventually required laryngectomy. There were no deaths. These results are compared to previous series on radionecrosis of the larynx in which hyperbaric oxygen was not used. This series indicates that hyperbaric oxygen therapy is a useful and effective adjunctive treatment modality in the management of laryngeal radionecrosis.
Chromophobe adenoma: evaluation and management.
Explore the source record for details and available documents.