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Biomedical subjects

W R Hudson

Publications and source records attributed to W R Hudson.

At least 37 records · Page 2Linked to original sources

Microbiology of beef carcasses before and after slaughterline automation.

The bacterial status of beef carcasses at a commercial abattoir was monitored before and after slaughterline automation. Bacterial counts did not differ significantly overall (P greater than 0.05) between the original manual line and the automated line for either morning or afternoon slaughter. On the manual line counts in the morning were lower than those from carcasses slaughtered in the afternoon, but on the automated line there was no difference between morning and afternoon counts. Due to highly significant line X sample site interaction for both morning and afternoon counts, overall differences among sample sites were not found by analysis of variance. However, principal components analysis revealed a significant shift in bacterial contamination among some sites due to slaughterline changes. The incidence of Enterobacteriaceae increased marginally following automation.

Analysis of Variance↗

A minimal apparatus method for counting bacteria: comparison with reference method in surveying beef carcasses at three commercial abattoirs.

In two surveys of three commercial abattoirs a minimal apparatus method for making bacterial counts, the "loop-tile' method, detected the same trends in bacterial numbers on beef carcasses as the ISO reference method applied to the same samples. Both methods showed the carcasses from one abattoir, that with an export license, to carry consistently higher numbers of bacteria, and one of the four sites sampled on each carcass to be consistently dirtier than the other three.

Abattoirs↗

Elevated serum secretory immunoglobulin A levels in patients with head and neck carcinoma.

Secretory immunoglobulin A (SIgA) is a major component of the secretory immune system and has been demonstrated in the sera of patients with various pathologic conditions. Current studies were undertaken to quantitate secretory components (SC) in sera of patients with squamous cell carcinoma in the head and neck region by means of a sensitive double-antibody radioimmunoassay. Patients with head and neck carcinoma were found to have threefold higher levels of SC (1.54 +/- 0.74 mg/ml) compared to normal controls (0.51 +/- 0.22 mg/ml, P less than .0001). Of interest was that the sera of patients who had successfully been treated 2 to 6 months prior to the study demonstrated statistically lower levels than those of patients with untreated carcinoma or recurrent disease. SC in sera appears to be in the form of SIgA. The origin and diagnostic significance of SC are briefly discussed.

Aged↗

Unilateral polyposis and mucoceles in children.

Children presenting with unilateral opacification of one or more of the paranasal sinuses must be considered at risk for serious disease. If an expansile lesion is noted, the most likely diagnosis is that of mucocele. Six children are presented with such findings and the diagnosis and treatment discussed. In five polyps were noted, indicating a probable allergic origin. Radiographic evaluation of the lesion is stressed with emphasis on the value of tomograms.

Airway Obstruction↗

The bacteriological quality of minced beef in the U.K.

Minced (ground) beef from three supermarkets, three intermediate-sized chain butchers and three small family butchers in each of three geographical areas was examined three times in warm weather and three times in cool. The total viable count (37 and 20 degrees C), numbers of Enterobacteriaceae (37 and 17 degrees C), and presumptive coliforms did not differ significantly between shop type or season. Statistically significant differences in numbers of faecal Streptococci, Staphylococcus aureus and Clostridium perfringens were too small to be of commercial importance, or diagnostic value.

Animals↗

The effect of incubation temperature and site of sampling on assessment of the numbers of bacteria on red meat carcasses at commercial abattoirs.

Several sites on commercial beef, pork and lamb carcasses were sampled at the end of the slaughterline. Total viable counts (TVC) of bacteria were assessed by incubation at 37, 20 and 1 degree C in addition to presumptive coliforms (PC), Enterobacteriaceae (ENT) and faecal streptococci (FS). Statistical analyses showed consistently dirty sites within an abattoir but these sites varied from one abattoir to another. Inter-site differences were unaffected by the incubation temperature of the TVC. Numbers of PC, ENT and FS did not mimic TVC. Empirical sampling plans are proposed to detect the highest count on a carcass by bulking samples from known dirty sites. At the end of the slaughterline TVC 37 degrees C is the most useful bacteriological index.

Abattoirs↗

Tomographic diagnosis of palatal defects.

We present the results of a pilot study conducted to evaluate the effectiveness of palatal tomography in patients suspected of having palatal defects not detectable by other methods. Twelve patients were involved in the projects, ranging in age from 3 to 11 years. There were 8 boys and 4 girls. Each patient was evaluated with voice recordings, lateral cineradiographic x-rays, and palatal tomograms. Nine of the 12 patients were found by tomography to have palatal defects that had not been detected either by cineradiography or by clinical investigation, including physical examination of the palate. The results of this study are presented with clinical findings.

Child↗

A minimum-volume, flow-through system for rearing frog tadpoles: aquarium.

A flow-through system requiring a low flow rate (4-10 ml/minute/aquarium) was developed for rearing tadpoles. This permitted tadpoles to be raised in tap water that had been dechlorinated and acidified. The aquarium consisted of a 7-liter plastic outer shell. A screen-bottomed basket, inserted into the shell, facilitated handling of the tadpoles. A bottom-scraper and flushing system permitted periodic removal of solid wastes.

Animals↗

Diagnosis of palatal defects by trispiral tomography: a pilot study.

A pilot study is presented in which 12 selected patients, ages 3-11 years, were evaluated for a palatal defect utilizing trispiral tomography. Each patient, because of speech and hearing abnormalities, was evaluated by a speech pathologist and an otolaryngolgist and voice recordings, audiometry, tympanometry and plain and cine radiographic X-rays were obtained. Those children with speech and hearing abnormalities in whom the question of a palatal defect was raised underwent trispiral palatal tomography. Nine of the 12 patients selected for tomography demonstrated a palatal defect that was not detected by other means. Trispiral tomography appears to be a useful tool in the diagnosis of suspected palatal defects in selected patients.

Child↗

Sjögren's syndrome and serous otitis media.

Extrasalivary lymphoid abnormalities in Sjögren's syndrome are well described. Patients have been found to have lymphoid infiltration of many organ systems. The nature of the lymphoid abnormalities constitutes a spectrum ranging from benign to malignant disease. A case of an elderly patient with long standing Sjögren's syndrome is presented because of the unusual manifestation of a benign lymphoid mass in the nasopharynx producing unilateral eustachian tube obstruction and serous otitis media. Serous otitis media associated with Sjögren's syndrome is recognized, but to our knowledge in previous cases an extrasalivary lymphoid abnormality has not been implicated as the underlying pathology.

Aged↗

Rhincerebral phycomycosis and internal carotid artery thrombosis.

This is a report of a case of internal carotid artery occlusion associated with rhinocerebral phycomycosis. In 18 autopsied similar cases that have been reported previously, hyphae were described in the walls of the internal carotid artery. Four survivors have been reported even though arteriograms demonstrated internal carotid artery occlusion, and a high index of suspicion for this complication should be maintained in all patients with rhinocerebral phycomycosis.

Adolescent↗

Angioneurotic edema. A review of modern concepts.

We review the subject of angioneurotic edema with special emphasis on the more clearly defined entity of hereditary angioneurotic edema. The clinical presentations of the various forms of angioneurotic edema are discussed. Attention is directed toward the attempts that have been made to define this group of diseases in terms of their underlying biochemical mechanisms. A simplified schema of the serum complement system is presented. We conclude that only after we understand such biochemical interactions will we able to effect a more definitive form of therapy for the angioneurotic edemas.

Acute Disease↗

Aspergillosis of the paranasal sinuses.

Aspergillosis of the paranasal sinuses may occur as a chronic disease in an otherwise healthy person. This infection is usually confined to a single paranasal sinus, the maxillary antrum, though it can involve the orbit and may initiate with findings of proptosis and decreased vision. The disease is characterized by a wide range of initial symptoms, and should be considered as a possible diagnosis in sinusitis refractory to antibiotics and antral lavage. Conservative surgical debridement of involved tissues and drainage of sinus, with or without adjunctive antifungal therapy, results in cure of this disease.

Adolescent↗

Cerebrospinal rhinorrhea: diagnosis and management.

The role of the otolaryngologist in the diagnosis and management of cerebrospinal fluid rhinorrhea is discussed. One hundred eight cases of cerebrospinal rhinorrhea were studied with emphasis on cause, localization, and treatment. Extracranial approaches produce minimal morbidity and should be considered as possible treatment for every patient with cerebrospinal rhinorrhea with leaks located in the frontoethmoid complex, cribriform plate, or sphenoid sinus region.

Cerebrospinal Fluid Rhinorrhea↗