In the rat, the autosomal recessive toothless (t1) mutation exhibits an acute form of osteopetrosis. This gene is not an allele of either ia or op that causes respectively, a transitory and acute form of the disease. Comparative radiographic study of t1/t1 and op/op mutants reveals some differences in respect to the size and shape of long bones. In contrast to op/op mutants, homozygous t1/t1 animals failed to respond to either parabiosis or bone marrow transplants.

Alleles↗

PubMedDate not supplied

4-Hydroxybutyrate as an anesthetic agent for the rat.

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Anesthesia, General↗

PubMedDate not supplied

Osteopetrosis with associated unerupted dentition in the albino rat.

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Alanine Transaminase↗

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Latex spheres as immunologic markers to demonstrate the binding of human salivary immunoglobulins to Streptococcus mutans.

The results of this study indicate that latex beads can be used to identify specific antigen-antibody interactions on the surface of bacterial cells. The application of a Labelling Index allowed specific interactions to be quantitatively distinguished from non-specific latex bead attachments. The labeling indexes for latex beads absorbed to anti-salivary immunoglobulins were significantly higher than for negative control indexes when tested against S mutans treated with saliva. Conversely, there was no significant difference when they were tested against nonoral bacteria treated with saliva. This suggests that both whole and parotid human saliva contained specific antibodies against S mutans.

Binding Sites, Antibody↗

PubMedDate not supplied

Pulpal responses to cavity drying.

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Air↗