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Biomedical subjects

W R Cheek

Publications and source records attributed to W R Cheek.

25 records · Page 2Linked to original sources

Thalamic tumors.

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Adolescent↗

Cerebellar hemorrhage in the term neonate: developmental and neurologic outcome.

To elucidate the effects of cerebellar hemorrhage on the term neonate, neurodevelopmental assessments were conducted at a mean age of 32 months on six children. In addition to cerebellar hemorrhage, ventriculomegaly was present on each subject's initial computed tomographic scan. All were managed without surgical evacuation. Two patients required shunts for progressive ventriculomegaly. Five patients had follow-up computed tomography indicating mild atrophy of the superior anterior vermis of the cerebellum; however, none had abnormal ventricular size or abnormalities of the cerebrum. On detailed examination conducted between the ages of 18 and 48 months, five had hypotonia, truncal ataxia, and intention tremor; two had nystagmus. Only one patient walked independently. Intellectual performance of four patients was within the retarded range and two had mildly delayed development. Two patients had markedly disordered expressive language. These data suggest that term neonates surviving cerebellar hemorrhage have neurologic deficits related to the site of hemorrhage, and cognitive deficits related to more generalized cerebral insult.

Brain Damage, Chronic↗

Spinal metastasis in primitive neuroectodermal tumors (medulloblastoma) of the posterior fossa: evaluation with CT myelography and correlation with patient age and tumor differentiation.

Twelve consecutive children with primitive neuroectodermal tumors of the posterior fossa (PNET-PF) were evaluated for spinal metastases with CT metrizamide myelography (CTMM) in the early postoperative period. Metastases were identified in 5 children (42%) and all were noted to have deposits in the thoracic region. All children with metastases were less than 3 years old and had differentiated PNET-PF.

Adolescent↗

Two siblings with the Chiari I malformation.

Two siblings with symptoms characteristic of the Chiari I malformation are described. The malformations were confirmed by magnetic resonance imaging scans and at surgery. Upon review of the world literature, no instance of the Chiari I malformation in a single family has been reported.

Arnold-Chiari Malformation↗

Scalp hamartoma in identical twins.

Identical twin male infants had scalp hamartomas removed from the occipital region. The histologic features and genetic implications of these unusual lesions are discussed.

Diseases in Twins↗