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Biomedical subjects

W Pirsig

Publications and source records attributed to W Pirsig.

At least 109 records · Page 6Linked to original sources
PubMed1984

Growth activities of the nasal septal cartilage in acromegaly.

Growth activity in different areas of human septal cartilage was measured by in vitro incorporation of 35 S-labelled sulfate and 3 H-labelled thymidine in 6 acromegalic patients. Septal cartilage was obtained during transnasal hypophysectomy. The growth activities in the posterior area, which is situated anterior to the septo-ethmoidal junction were significantly enhanced compared to a control group of hormonally normal adults. Growth activities of the septal cartilage in the anterior free end and the suprapremaxillary area were not different in both groups. This indicates that growth hormone excess in acromegaly enhances human septal growth by stimulation of growth activities in the posterior area and not at the anterior free end and suprapremaxillary area.

Acromegaly↗
PubMed1984

[Indications, technic and long-term results of surgery of the nasal pyramid and septum in children].

Since the operation of submucous resection of the septum has been replaced by septoplasty, the indication for nasal surgery in children has increased. They may be divided into four categories, which by order of importance are: Re-establishment of nasal function (95%); severe nasal allergy provoked by deformity; psychological factors associated with deformities and cosmetic factors related to gross congenital deformities. Septoplasty must preserve three zones: Central zone, the anterior edge of the septum and supra-premaxillary region. Rhinoplasty is less dangerous than septoplasty in children. Surgery of the turbinates is often necessary in conjunction with the preceding operations. The authors present several examples of long term results (before and after puberty).

Child↗
PubMed1984

[POR 8 (ornipressin). Local vasoconstrictive effect and hemodynamic activity during surgery in ENT clinics].

POR 8 (ornipressin) at a concentration of 5 IU in 10 ml of 1% lidocaine was used as a local vasoconstrictor in 262 ENT operations. Anaesthesia was carried out with either halothane or enflurane, or with diazepam and fentanyl. The doses of POR 8 lay between 2.7 IU and 3.5 IU. Under inhalational anaesthesia there was a good vasoconstriction in 85% to 90%, and anaesthesia with diazepam-fentanyl in 60% to 83% of cases, depending on the site of operation. There should be a 10-20 minute interval between infiltration and the beginning of surgery. Under inhalational anaesthesia the systolic blood pressure fell by 10% after infiltration of POR 8, when the diastolic blood pressure rose by 6%. During diazepam-fentanyl anaesthesia the systolic blood pressure increased by 23%, the diastolic by 27%. POR 8 was not found to have an antidiuretic effect. There was no difference between the osmolality, sodium and potassium levels of 30 patients measured before infiltration and 24 hours later. Because of the minimal side effects of POR 8 on the cardiovascular system during inhalational anaesthesia we recommend the use of these substance as a local vasoconstrictor instead of epinephrine.

Anesthesia, Inhalation↗
PubMed1984

[Surgery of the nose in childhood: growth and late results].

First of all the article reviews data on the normal and pathological growth of the nasal region. It can be said that sequelae of nasal trauma in early childhood often become more prominent during the puberal growth spurt, especially in the osseous parts of the nose. Following a brief survey of the surgical techniques, the long-term results of septal correction and of functional rhinoplasty in children are presented. Recurrences of deviations in the nasal skeleton can be found in about 20 per cent of the patients, and in about 30 per cent for the cases who had been operated on during the puberal growth spurt.

Adolescent↗
PubMed1984

[Acute epiglottitis in childhood].

Report on 44 cases of acute epiglottitis in childhood. All of these had typical local findings and there was positive proof of bacterial growth. The incidence and occurrence of symptoms and principal signs is discussed. The high incidence of wrong diagnoses is remarkable. 4 out of 44 patients died before reaching a hospital or due to hypoxia. A concept is presented covering preclinical diagnostics and therapy, appropriate care during transport in the first-aid ambulance, and clinical treatment in the hospital.

Acute Disease↗
PubMed1983

Growth activity in human septal cartilage: age-dependent incorporation of labeled sulfate in different anatomic locations.

Growth activity in different areas of human septal cartilage was measured by the in vitro incorporation of 35S-labeled NaSO4 into chondroitin sulfate. Septal cartilage without perichondrium was obtained during rhinoplasty from 36 patients aged 6 to 35 years. It could be shown that the anterior free end of the septum displays high growth activity in all age groups. The supra-premaxillary area displayed its highest growth activity during prepuberty, showing thereafter a continuous decline during puberty and adulthood. A similar age-dependent pattern in growth activity was found in the caudal prolongation of the septal cartilage. No age-dependent variations could be detected in the posterior area of the septal cartilage.

Adolescent↗
PubMed1983

Ornipressin as vasoconstrictor in rhinosurgery.

The haemostatic effect of a high concentration of ornipressin 5 IU/10 mls lidocaine was studied in 127 patients undergoing rhinosurgery under two types of general anaesthesia. Under halothane/enflurane anaesthesia blood pressure and heart rate remained nearly constant up to 15 minutes following local injection of ornipressin into the nasal tissues. Good haemostasis was achieved in 86.5 percent of cases. Under diazepam/fentanyl anaesthesia an elevation of blood pressure was observed following infiltration of ornipressin. Thus the high concentration cannot be recommended for cases with blood pressure dyscrasias. The haemostatic effect was either good in only 60 percent of the patients.

Anesthesia, Inhalation↗
PubMed1983

[Hairy nasopharyngeal polyp as a respiratory emergency].

Respiratory distress and a total airway obstruction in an newborn was caused by a mobile tumour in the pharynx. Urgently it had to be fixed with holding suture under traction. Surgical resection revealed a bipartial hairy tumour based on the lateral pharyngeal side of the soft palate. The histologic examination showed: fat tissue, cornified epidermis and sebaceous glands, but no further signs of teratoma. Further complications as Pneumothorax and necrotising entercolitis could be managed.

Emergencies↗
PubMed1982

[Septum deviation 1882: beginning of systematic submucous septum surgery].

The submucous resection of the nasal septum which became well-known all over the world in the beginning of our century through Killian and Freer, has been practised in a few isolated cases since 1847. However, its systematic use started around 1882 by Ingals in Chicago and by Hartmann, Krieg, and Petersen in Germany. The development of this operation is shown against the background of the anatomico-pathological knowledge and surgical conditions prevailing around 1882, and is compared with the contemporary methods for the treatment of the septal deviation.

Germany↗
PubMed1982

[Behaviour of growing septal cartilage after autogenous transplantation into the retroauricular region (author's transl)].

In five children and one adolescent biopsies of the septal cartilage partially covered with inner perichondrium, were removed during septoplasty and buried into the retroauricular region for 1.8 to 5.3 years. After removal the implants were equal or reduced size. Histologically the cartilage showed its original structure in three children who were before their puberal growth spurt at the time of the removal of the implant. In the other three who were beyond this growth spurt the septal cartilage was partially or nearly totally ossified. The presence of the innermost perichondrium may prevent resorption of the cartilage. At the borders of the cartilage without perichondrium signs of resorption were more marked in the elder group than in the younger.

Adolescent↗
PubMed1980

Tumour of the ethmoid with intracranial and intranasal growth.

The case of an 18-year-old female patient suffering from a hemangiopericytoma with intracranial, and paranasal and intranasal extension is described. Before the diagnosis was fully established a partial tumour removal was performed by a nasal surgeon, because the nasal airways were obstructed. Later on, because of the risk of infection, a decision against radical operation was made. The patient was treated by radiation, but the tumour did not respond and she was transferred to the neurosurgical department where the haemangiopericytoma was completely removed. A pericranium-skull flap was used to close the basal defects of dura and skull. The advantage of this technique over other procedures is the safe closure of the intracranial cavity, thus permitting a radical removal of an intracranial-intranasal tumour in one operation.

Adolescent↗
PubMed1980

[A contribution to the history of the treatment of middleface-injuries (author's transl)].

The first descriptions of facial injuries, especially about hurts of the nose, their diagnosis and their treatment are found in the writings of the old cultures. There are already corresponding references in the Papyrus Edwin Smith and in the Papyrus Ebers. There exist descriptions of the surgery of India and in the papers of Hippocrates, which contribute details to these injuries and their treatments. Here it is pointed to the splinting of the septum by inserting open tubes. A careful bandage, respecting the rebuilding of the nose, and the reposition of lower jaw fractures are remarked. In the Middle Ages there were some innovations in wound-treatment, especially in the technique of suture, but no important innovations in the medical care of middleface-fractures. There are only some modifications in the special treatment, but the surgeons always refer to the already available therapy-methods, mainly to those of Hippocrates. Only towards the end of the 18th century and the beginning of the 19th century, these themes, particularly the treatment of upper jaw hurts, got new impulses by Graefe, Lang and Le Fort, who also worked out new methods of the external and internal fixation by wire.

Facial Injuries↗
PubMed1980

[Immediate implantation of preserved cartilage in suppurative perichondritis of the auricle (author's transl)].

Following satisfactory experiences in the treatment of abscesses of the nasal septum, preserved rib cartilage without its perichondrium was used in the immediate reconstruction of the pinna following the excision of all diseased cartilage and granulation tissue in patients with suppurative perichondritis, according to the technique of Herrmann and Boenninghaus. This prevents shrinkage and the inevitable deformity of the auricle and is demonstrated in three typical cases. In one child the graft induced a partial regeneration of autogenous fibrous cartilage, and later preserved auricular cartilage was successfully transplanted.

Abscess↗
PubMed1979

Histopathology of 30 non-operated acoustic schwannomas.

Thirty of 1720 temporal bones from the Wittmaack's Collection contain nonoperated acoustic neuromas, 22 of them large tumors. Histologically, each tumor has to be considered as an individual. Most of the tumors show a mixture of Antoni type A and B. Tumor vascularization is pronounced in half the cases. Vessels of the internal acoustic meatus are found in all cases. Protein contents of the perilymphatic spaces is medium to pronounced in 23 of 30 cases in comparison to the small protein contents of the healthy side. Ganglion geniculi is invaded in 11 cases (9 von Recklinghausen's disease), Ganglion Scarpae in 26 cases (9 von Recklinghausen's disease), and Ganglion spirale in 9 cases (7 von Recklinghausen's disease). Cochlear and vestibular nerve fibers within the internal auditory meatus were affected by the tumor in 28 of 30 cases, the facial nerve only in 11 cases, among them 9 cases of von Recklinghausen's disease. Twenty-six of 30 schwannomas have a portion within the cribriform area of the cochlea fundus, which explains the limitation to radical tumor surgery without damage of the cochlear nerve. These histological findings explain the site of damage of hearing to expand between the cochlea to the auditory brain stem nuclei, and support the audiological experience that a correlation of "acoustic neuroma" and "retrocochlear lesion" is often not correct.

Adolescent↗