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Biomedical subjects

W Pedersen

Publications and source records attributed to W Pedersen.

26 records · Page 2Linked to original sources
PubMed1989

Patterns of drug use and sensation-seeking among adolescents in Norway.

The relationship between personality and drug use was investigated by studying patterns of sensation-seeking behaviour and drug use among adolescents. A questionnaire was distributed to a sample of 1027 Norwegian senior high school students aged 16 to 19 in the greater Oslo area. The response rate was 97%. The sensation-seeking subscores showed moderate to strong association with the use of the different drugs. A canonical correlation analysis yielded 3 significant variates: in the drug use domain the first dimension correlated with the use of legal drugs and inhalants, the second with cannabis and tranquillizers and the third with tobacco. In the sensation-seeking domain the first dimension was almost synonymous with the disinhibition scale, the second with experience-seeking, and the third correlated highly negatively with thrill-, adventure- and experience-seeking. The results support the assumption that a strong link exists between sensation seeking and drug use. They further show the importance of taking different subdimensions of the sensation-seeking trait into account for prevention and treatment of drug use and abuse.

Adolescent↗
PubMed1987

Jet-nebulized beclomethasone dipropionate in the management of bronchial asthma. Topical steroids for asthmatic children younger than 4 years.

The efficacy of jet nebulized beclomethasone dipropionate (BDP) in the management of asthma was evaluated in 18 children, 2-26 months old (mean 10 months). The children were selected on the basis of the severity of their symptoms and the lack of effect of conventional treatment. The effect of BDP was evaluated by comparing clinical data before and after the initiation of treatment. Fifteen of the 18 patients experienced a significant clinical improvement during treatment with BDP. BDP "nebulizer solution" is a valuable contribution to the management of severe asthma in young asthmatics.

Administration, Inhalation↗
PubMed1985

Age-dependent decreases in human submandibular gland flow rates as measured under resting and post-stimulation conditions.

Submandibular saliva samples were obtained with a new collection device, under resting and post-stimulation conditions, from 28 healthy individuals between 70 and 91 years of age, and from 30 healthy individuals between 18 and 39 years of age. The salivary flow rates were significantly decreased in the aged group compared with the control group. The mean resting and post-stimulation flow rates for the aged group averaged 22% and 39%, respectively, of control values.

Adolescent↗
PubMedDate not supplied

Exclusion of atrial thrombus by transesophageal echocardiography.

To determine whether transesophageal echocardiography (TEE) is useful in ruling out the presence of atrial thrombus, we performed TEE in 20 patients immediately before valve replacement or valve repair and within 3 days of an autopsy in one patient. Mitral stenosis was the predominant lesion in three patients, mitral regurgitation was seen in 11 patients, five patients had mitral prosthesis malfunction, one patient had a tricuspid prosthesis malfunction, and one patient had aortic stenosis. Eight patients were in atrial fibrillation. Four patients demonstrated spontaneous contrast in the associated atria. Nine patients were receiving oral anticoagulation. Mean left atrial diameter was 5.3 +/- 1.3 mm. TEE revealed no evidence for atrial thrombus in 18 of the 21 patients; this finding was confirmed by careful inspection of the atria including the appendages. TEE demonstrated a left atrial thrombus in two patients and a right atrial thrombus in another (confirmed at the time of surgery or at autopsy). In all cases transthoracic echocardiography was negative. Our data suggest that TEE is useful in ruling out atrial thrombus, and therefore may be a useful test preceding interventions associated with an increased risk of embolism from the atria such as cardioversion, mitral valvuloplasty, or valve replacement.

Adult↗