Proceedings: The assessment of results of surgery for peptic ulcer.
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Biomedical subjects
Publications and source records attributed to W P Small.
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The assessment of the result of surgery for peptic ulcer is based on doctor-determined criteria. Failure to distinguish one operation as being better than another may be because these criteria do not include the patient's rating of outcome. A questionnaire based on patients' descriptions of the quality of result has been tested in 63 patients. Preliminary figures show that success in the opinion of the patient does not necessarily mean absence of symptoms, while failure is due more to psychosocial than physical factors. A logical step in the planning of controlled trials is preoperative control of admission to the trial.
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The clinical data are presented of two women with profound metabolic upset from exceptional water and electrolyte losses in diarrhoea. One had an islet-cell adenoma of the pancreas and the other abnormal islets. Gastric and pancreatic function were abnormal in both, consistent with the subsequent demonstration of a pancreatic and choleretic secretagogue in the tumour tissue and pancreatic and gastric secretagogues in circulating blood (Cleator, Thomson, Sircus, and Coombes, 1970).
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