Mammalian embryonic hemoglobins.
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Amino Acid Sequence↗
Biomedical subjects
W Ostertag
Publications and source records attributed to W Ostertag.
Clinical studies and physiological properties of Hopkins-2 haemoglobin.
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Adult↗
Hemoglobin-Lepore-Baltimore, a third type of a delta, beta crossover (delta 50, beta 86).
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Black or African American↗
Hb Sinai, a new alpha chain mutant alpha his 47.
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Amino Acids↗
The mutagenic action of caffeine in higher organisms.
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Animals↗
Differentiation of rabbit blastocysts in vitro.
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Animals↗
[Caffeine and theophyllin mutagenesis in cell and leukocyte cultures of man].
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Caffeine↗
The action of proflavin and actinomycin D in causing chromatid breakage in human cells.
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Acridines↗
The mutagenic activity of caffeine in man.
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Caffeine↗
Transformation of mononuclear phagocytes in vivo and malignant histiocytosis caused by a novel murine spleen focus-forming virus.
The study of retrovirus-induced leukaemias in mice is a powerful tool for the elucidation of the normal regulation of the haematopoietic system. The acute murine spleen focus-forming viruses (SFFV) can be classified according to the haematopoietic lineage on which they exert their effects in the adult mouse. Here we report a new SFFV isolate, the AF-1 virus, with the novel ability to transform cells of the mononuclear phagocyte lineage. The virus was isolated from sarcomas that were induced on passage of a cloned Friend helper virus (F-MuLV, 643/22F) in newborn BALB/c mice. We have cloned the transforming defective subunit of the AF-1 viral complex in NRK cells and isolated several subclones. Analysis of the proviral genome in two non-producer cell clones reveals that AF-1 virus contains Harvey v-ras-specific sequences (Fig. 1). Thus, AF-1 virus is closely related to Harvey murine sarcoma virus (Ha-MSV), and is, at present, the only tool by which permanent cell lines can be obtained from mononuclear phagocytes in the mouse.
Animals↗