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Biomedical subjects

W O Chukudebelu

Publications and source records attributed to W O Chukudebelu.

At least 19 recordsLinked to original sources
PubMed1989

Antenatal screening for syphilis at the University of Nigeria Teaching Hospital, Enugu, Nigeria--a six year survey.

Between January 1979 and December 1984, 29,083 out of 42,515 antenatal patients booking at the Antenatal Clinic of the Department of Obstetrics and Gynaecology of the University of Nigeria Teaching Hospital, Enugu, underwent full screening for syphilis. The results showed that 890 patients (3.06%) had positive VDRL test. Of those that reacted positively in the VDRL test, 103 (11.6%) had positive TPHA test. A prevalence rate of sero-positivity of 0.35% was obtained indicating a low incidence of syphilis in our pregnant women compared with results from other parts of Nigeria. A strong recommendation was made to treat all seropositive cases whether there was historical or clinical confirmation of syphilis or not.

Female↗
PubMed1989

Incidence of yeasts in pregnant and non-pregnant women in Nigeria.

The yeast flora of vagina and associated sites (cervix, urethra, perineum and rectum) in 224 pregnant and 106 non-pregnant Nigerian women was investigated. A variety of yeasts represented by 12 species were isolated. Candida albicans was the most frequently isolated species in both groups, accounting for 63.6% of the isolates from pregnant women and 44.8% of the isolates from non-pregnant women. Other species of yeasts infrequently or occasionally encountered were Torulopsis glabrata, C. tropicalis, C. pseudotropicalis, C. parapsilosis, C. krusei, C. guilliermondii, C. stellatoidea, T. candida, T. etchellsii, Saccharomyces cerevisiae, Rhodotorula rubra and Cryptococcus uniguttulatus. C. albicans was also the principal species recovered from symptomatic cases in both groups, followed by T. glabrata in pregnant women and C. parapsilosis in non-pregnant women.

Adolescent↗
PubMed1988

Maternal mortality in Anambra State of Nigeria.

The maternal mortality rate (MMR) in 10 hospitals scattered all over Anambra State in a 5-year period was studied. The hospitals covered urban, semi-urban and rural areas. The MMR varied from 1.8 to 13 per thousand with a mean of 4.97 per thousand. The causes of and various factors influencing this high mortality rate are examined as well as the avoidable factors. Suggestions are made for its reduction based on accurate data collection, improved health facilities, improved socio-economic status and basic education.

Adolescent↗
PubMed1981

Appendices removed at cesarean section: histopathology.

Appendices removed from 100 healthy Nigerian Igbo women during elective cesarean operation and examined microscopically as three random cross sections showed that lesions categorized as luminal pus, luminal fibrosis, mucosal ulceration, muscular inflammation, crypt abscess and crypt necrosis were present in numerous sections. As elsewhere, these asymptomatic patients might have had clinical acute appendicitis in the puerperium. to explain the possible outcome in the rest of such patients, the crypt of Lieberkühn was advanced as a research-worthy histopathologic unit. Thus, in the natural history of the disease, both crypt abscess and crypt necrosis are contrastable bipolar lesions. In all probability, worldwide research on these intriguing lesions will reveal crucial clues to one or more facets of the pathogenesis of appendicitis. [Key words: Appendicitis, pathogenesis; appendix, histopathology]

Abscess↗
PubMed1981

Pelvic abscess in gynecologic patients.

A survey of an 8-year period in which 37 cases of pelvic abscess occurred in a Nigerian hospital department of obstetrics and gynecology is presented. All 37 women were surgically treated; one death occurred postoperatively. A regimen of 400 mg of metronidazole three times daily combined with appropriate antibiotics is recommended as the treatment of choice, even where laboratory confirmation of anaerobic involvement is unavailable.

Abortion, Induced↗
PubMed1981

The iron status of anaemic pregnant Igbo women in Nigeria.

The iron status of 120 anaemic pregnant Igbo women was investigated. Of the 120 patients whose haemoglobin was less than 10%, 30 (25%) had iron deficiency anaemia; 89 (74%) had megaloblastic anaemia (most probably due to folate deficiency), while 1 had Hb sickle cell disease. Malaria parasites were detected in only 7.5% of our patients, and seemed not to have a important factor in the causation of anaemia.

Adolescent↗
PubMed1980

Child spacing and child mortality among Nigerian Igbos.

Until recently, a birth interval of at least two years was the norm in the Nigerian Igbo culture, a practice necessary for infant health and survival. A study of antenatal patients of the University of Nigeria Teaching Hospital, Enugu, Nigeria, shows that this cultural pattern has been disrupted by Westernization, urbanization and consumerism. The patients studied had an average of four pregnancies in five years. Roughly half of those conceived did not survive: 41% of the patients reported having lost at least one child. Modern family planning methods are urged as replacements for the abandoned traditional methods of child spacing.

Adolescent↗
PubMed1978

Burst abdomen following cesarean section.

Fifty-one cases of burst abdomen occurred following 1 988 cesarean sections performed at the University of Nigeria Teaching Hospital over a 5-year period. The incidence of this occurrence was 2.6% (2.3% if all laparotomies in both obstetrics and gynecology are combined). The risk was three times as great for "unbooked" patients, who were first seen in labor. Possible etiologic factors and preventive measures are discussed.

Abdominal Muscles↗