Histological examinations of the palatine glands were performed in 100 postmortem cases and 65 biopsies of outpatients. These data were related to personal characteristics, such as age, sex, denture-wearing and certain primary diseases. The histological results of the postmortem material were found to be only partly comparable to those of the biopsy specimens. The pathohistological findings in the parenchyma of the outpatients proved to be less pronounced in the individual groups than those of the postmortem cases. An evaluation of the postmortem findings showed inflammatory, ectatic and metaplastic alterations of the ducts as well as atrophies and inflammations of the parenchyma, particularly in baseplate denture wearers and with increasing age. In persons under 65 the tissue irritation caused by baseplate dentures resulted in increased gland and duct alterations. In the dead above 65 the difference between age-dependent and denture-induced alterations of the parenchyma was statistically immaterial.

Aged↗

PubMedDate not supplied

[Ultrastructural studies on obstructive palatal sialadenitis in denture wearers].

The ultrastructural phenomena of obstructive palatal sialadenitis were studied in 7 denture wearers versus 3 non-denture wearers as control. Apart from mucositis severe stagnation of salivary flow in the excretory ducts was observed in patients with dentures with short periods of service. In contrast to the control group there were mucous droplets after exocytosis of the acinus cells that remained intact even in the lumina of the distal excretory ducts. Desquamation of the duct and acinus cells results in a change in the organic components of the secretory mucus. The periductal infiltrate consisted mainly of plasma cells and lymphocytes, whereas neutrophils or macrophages were not observed. Ultrastructurally there was no evidence of an ascending microbial infection of the ducts. Probably, infections do not play an important role in the pathogenesis of obstructive palatal sialadenitis.

Adult↗

PubMedDate not supplied

[Physiology and pathophysiology of the minor salivary glands].

Measurements of the secretory rates of the palatine and the parotid glands, assessing the electrolyte content of all salivary fractions and combined clinical biotic studies underline the clinical importance of the minor salivary glands. The minor salivary glands are shown to be organs whose function is decisively involved in symptoms such as xerostomia, stomatodynia, and what is known as "denture intolerance". Moreover, proper secretion of the palatine glands is of crucial importance for the physical retention of maxillary full dentures. There are no connections between secretory rates of major and minor salivary glands. The effect of certain drugs on salivary production and thus on the symptoms of hyposalivation seems to be considerable. Treatment methods for inadequate salivary secretion are outlined. The adaptive tendency of properly functioning palatine glands appears to be high. The fact that atrophic and dystrophic processes can be functionally compensated to a relatively high degree speaks for the dynamic capability of the glandular parenchyma. In view of the clinical relevance of the minor salivary glands it is mandatory that the functional principles and control mechanisms underlying their secretion be investigated in future studies.

Calcium Channel Blockers↗

PubMedDate not supplied

[Immunohistochemical studies on palatinal salivary glands].

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Dentures↗

PubMedDate not supplied

[Morphometry and distribution of the palatine glands in denture wearers and non-denture wearers].

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Age Factors↗