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Biomedical subjects

W Mortensson

Publications and source records attributed to W Mortensson.

101 records · Page 6Linked to original sources
PubMedDate not supplied

Suprarenal haematoma versus neuroblastoma complicated by haemorrhage. A diagnostic dilemma in the newborn.

Concomitant neonatal suprarenal haemorrhage and neuroblastoma is rare. The clinical and radiologic manifestations recorded in 11 patients with this entity are compared with the findings in 32 cases with simple adrenal haemorrhage. Because of the many similarities in presentation the combined lesion must always be considered when a neonate is found to have a retroperitoneal, extra-renal mass. Our present approach to the investigation includes conventional chest and abdominal radiography aimed to demonstrate possible paravertebral widening. Serial ultrasonographies are easy to carry out and indispensable. The low specificity of urography makes us refrain from this modality as a routine. Scintigraphy, in infants and children considered useful in demonstrating extent and spread of neuroblastoma, has hardly been employed in neonates. The true value of the modality in this particular age group remains to be settled. CT scanning does not seem to provide essential information additional to that of sonography and may therefore be excluded from the protocol. Determination of urinary excretion of catecholamine metabolites is of crucial significance and a compulsory part of the investigation.

Adrenal Gland Diseases↗
PubMedDate not supplied

The course of bronchopulmonary dysplasia. A radiographic follow-up.

Forty-one low weight premature infants treated with intermittent positive pressure ventilation in infancy were followed clinically and with chest radiography for 4 to 6 years. One child died during the period (sudden infantile death) and 2 others were not available for follow-up examination. The abnormal chest pattern of bronchopulmonary dysplasia (BPD) resolved completely or improved during the period; residual changes were found in 34 per cent of the cases. The main part of the resolution occurred during the first 2 years. Mild BPD was more prone to heal. The persisting parenchymal changes--interstitial fibrosis or areas of hyperinflation or both--were generally slight. The frequency of infection of the lower respiratory tract was increased during the first 2 years of life and was positively correlated to the severity of the pulmonary abnormalities. The frequency of infection dramatically decreased during the subsequent 2 years.

Airway Resistance↗
PubMedDate not supplied

The validity of radiographic assessment of childhood transient synovitis of the hip.

The diagnostic significance of some radiographic signs (abnormal hip 'joint space' and periarticular fat layers) as indicators of hip joint effusion or hip complaints without effusion was studied with ultrasonography and radiography in 47 children (58 examinations), of whom 40 had acute unilateral transient synovitis. It was found that 'joint depth' was not influenced by presence of intra-articular fluid collections; blurring and/or displacement of the periarticular fat pads medial and lateral to the hip joint occurred more frequently when joint effusion was present than in symptom-free hips or in painful hips without effusion. The radiographic signs provided, however, too low diagnostic accuracy to be of practical value. It is suggested that ultrasonography of the hip joint is a valuable means in obtaining a better definition of the diagnosis transient synovitis.

Adolescent↗
PubMedDate not supplied

Value of bone scan in the McCune-Albright syndrome. Report of a case.

Bone scintigraphy proved valuable in diagnosing McCune-Albright's syndrome in a 6-year-old girl by detecting multiple, non-symptomatic foci in the skull, axial skeleton and in the extremities. Subsequent roentgen examination showed abnormal bone structure in the affected areas, consistent with fibrous dysplasia.

Bone and Bones↗
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Considerations in the corticosteroid treatment of bone cysts.

To be effective in treating bone cysts, intracavital injections of corticosteroids must be able to run freely over their lining membrane. Free movement may be prevented by complete or partial osseous or fibrous septa or by the cyst contents. This report illustrates such situations. To solve the problem, the interior anatomy of the cyst should be evaluated by a contrast study and then, when necessary, several corticosteroid injections should be made in different cyst compartments. The volume of corticosteroid should be modified according to the size of the cyst.

Bone Cysts↗
PubMedDate not supplied

Radiologic observations in severe neonatal respiratory distress syndrome treated with the isolated phospholipid fraction of natural surfactant.

Ten newborn babies with severe respiratory distress syndrome, all dependent on artificial ventilation, were treated via the airways with the isolated phospholipid fraction of bovine or porcine surfactant. After treatment with surfactant at a median age of 10.5 h, there was in all patients a striking improvement of lung aeration in chest films, with a decrease in parenchymal fluid retention and in distension of bronchioli. These radiologic findings were associated with a dramatic improvement of oxygenation and a significant reduction of the right-to-left shunt. In spite of the rapid therapeutic response, four patients died from cerebral hemorrhage. One of the surviving patients developed bronchopulmonary dysplasia. Our findings document efficacy of this new surfactant preparation in the neonatal respiratory distress syndrome, but the long-term effects need to be further tested in randomized clinical trials.

Blood Gas Analysis↗
PubMedDate not supplied

Scintigraphic evaluation of traumatic splenic lesions in children.

Ninety-eight children with recent blunt abdominal trauma which initially evoked clinical suspicion of splenic injury were examined with colloid scintigraphy of the spleen and the liver using multiple imaging views and with abdominal survey. Nineteen children were, in addition, examined with tomographic scintigraphy. The clinical findings and the course of the disorder were reanalyzed. Scintigraphy indicated splenic injury in 56 children and hepatic injury in another 5 children. The left lateral and the left oblique were the optimum imaging views for detecting splenic ruptures. Tomographic scintigraphy did not improve the diagnostic yield. Abdominal survey failed to indicate almost every second case of splenic rupture and provided no additional information of significance. The clinical review agreed with the scintigraphic diagnosis of splenic lesions but, in addition, it suggested possible splenic lesions in another 10 children with normal scintigraphy. This discrepancy cannot be explained as surgery was not employed; the occurrence of splenic lesions too small to become detectable at scintigraphy or to provoke clinically evident symptoms may be supposed.

Abdominal Injuries↗
PubMedDate not supplied

Ultrasonography of the kidney following renal biopsy in children.

The frequency of renal and perirenal hematomas following percutaneous renal biopsy using a cutting needle was studied by means of ultrasonography in 30 children and young adults aged 3-16 years. Hematomas occurred in 64.5 percent of the biopsies but caused significant clinical symptoms in one patient only.

Adolescent↗
PubMedDate not supplied

Prediction of the stability of minimally displaced fractures of the lateral humeral condyle.

Fractures of the lateral humeral condyle run a great risk of subsequent displacement. This is also true--although to a lesser extent--for primarily non-displaced or minimally displaced (less than or equal to 2 mm) fractures. The present retrospective investigation aimed at defining radiographic criteria in order to predict the stability of non-displaced or minimally displaced fractures in 159 children. The fractures were classified according to radiographic criteria into 3 groups considered to represent stable, ambiguous and unstable fractures. Additional displacement while immobilized in plaster occurred in 2.6 per cent of the fractures classified as stable and in 44.4 per cent of those classified as unstable (p less than 0.001); in the ambiguous group subsequent displacement occurred in 24.1 per cent. It is concluded that the radiographic criteria should be useful to predict the stability of non-displaced or minimally displaced fractures of the lateral humeral condyle in children.

Adolescent↗
PubMedDate not supplied

Chronic recurrent multifocal osteomyelitis in children. A roentgenologic and scintigraphic investigation.

Thirty cases of chronic recurrent multifocal osteomyelitis have been reported in the literature. A radiologic evaluation of thirty-one additional cases, 25 of whom also underwent bone scintigraphy, is presented. Bone biopsy specimens were obtained in 16 patients. Most lesions were located in the metaphyses of the long bones adjacent to the physis and had a characteristic, probably pathognomonic appearance. Extension into the epiphyses was rare. Lesions in the vertebral bodies, clavicle and pelvis had possibly a less specific radiographic appearance. Lesions in short tubular bones were non-specific. Bone scintigraphy had a practical value in evaluating the global distribution of lesions including asymptomatic lesions and lesions in the spine or pelvis, the latter being somewhat hard to detect with conventional radiography. All biopsies showed acute, subacute or chronic unspecific osteomyelitis, sometimes mixed in the same lesion. Staining for bacteria and fungi was negative.

Adolescent↗