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Biomedical subjects

W Matek

Publications and source records attributed to W Matek.

At least 37 records · Page 2Linked to original sources
PubMed1984

Initial experience with the new electronic endoscope.

With the introduction of an electronic sensor attached to the tip of a flexible endoscope, which functions in the manner of a television camera, new dimensions have been opened up for endoscopy. First reports on the clinical application of this new method have been presented at congresses held recently. We, too, were given the opportunity of trying out the prototype of an electronic colonoscope in four patients. This is a brief report of our findings.

Colonic Polyps↗
PubMed1983

[The electro-hydro-thermal probe. Clinical results and possible use of modified electrocoagulation in the gastrointestinal tract].

Electrocoagulation with simultaneous water infusion (electro-hydro-thermal probe) was applied in 58 patients. In 43 there had been active bleeding which was stopped in over 90%. The use of this probe thus proved to be of clinical importance for endoscopic arrest of bleeding. Non-bleeding lesions, most of them vascular changes, were coagulated in 15 patients, removing a potential source of bleeding. There were no complications.

Electrocoagulation↗
PubMed1983

The malignant potential of colorectal polyps--a new statistical approach.

To investigate the factors influencing the malignant potential of adenomas, a logit analysis was carried out. The malignancy rate (frequency of malignant areas infiltrating into submucosa) in adenomas is influenced by 1. the size of the adenoma, 2. the interrelationship between size and histological type (tubular, tubulo-villous, villous) and 3. the macroscopic growth pattern (pedunculated, semipedunculated, sessile). No influence is exercised by the number of adenomas, their localization, or the sex of the patient.

Adenocarcinoma↗
PubMed1983

Significance of polypectomy in the large bowel--endoscopy.

The precancerous and early stages of colorectal carcinoma are, in the vast majority of cases, known and pathologically unequivocally defined. The precancerous and early stages of colorectal carcinoma can be detected by routine diagnostic measures (colonoscopy) with an adequate degree of reliability. A curative treatment of precursor and early stages of colorectal carcinoma is possible. As a rule, the procedure used is endoscopic polypectomy. A lowering of the incidence rates and mortality figures of large-bowel carcinoma through the routine detection and thoroughgoing endoscopic treatment of precursors of colorectal carcinoma would appear possible. The conclusion follows logically from the established points 1 to 3. The significance of polypectomy in the large bowel, which today is carried out routinely using a standardized technique, is to be seen in the prevention and early detection of colorectal carcinomas.

Colonic Neoplasms↗
PubMed1983

[Electro-hydro-thermo probe in the therapy of gastrointestinal hemorrhage].

By developing the electro-hydro-thermo probe the known disadvantages of dry electrocoagulation were eliminated. Instillation of water prior or simultaneously during the coagulation allows to rinse and to localize exactly the bleeding site; adhering and contaminating of the tip of the probe is avoided. This is a report on the application of the electro-hydro-thermo probe in 51 patients of which 37 had an active bleeding, eight a recent haemorrhage according to Forrest II and III, and six had mostly multiple telangiectasias, angiomas or angiomatoses. The efficacy of the probe to stop bleeding is good. Only in two patients with penetrating gastric ulcer the coagulation had to be stopped prematurely because of the risks of primary perforation. In four patients with recurrent bleeding emergency surgery was necessary. There were no complications following coagulation with the electro-hydro-thermo probe. Emergency surgery is indicated in patients with active haemorrhage which cannot be endoscopically localized or successfully coagulated. In active bleeding coagulation using the electro-hydro-thermo probe is only a measure to improve the initial condition of the patient prior to surgery.

Electrocoagulation↗
PubMed1982

[Diagnostic endoscopic assessment of the irritable colon syndrome (author's transl)].

The diagnosis of irritable colon was found in about 50% of 227 patients who showed increased colonic contractions at colonoscopy. In 1240 patients without unusual motility of the colon during colonoscopy this diagnosis was made only in every twelfth case. Increased contractions of the colon observed during colonoscopy are thus a symptom of the irritable colon. When clinical complaints are taken into account this symptom has a diagnostic value of 90%. However, it is not pathognomonic for functional intestinal complaints as it does not occur in all patients with irritable colon and it can also be demonstrated in patients without evidence of functional gastrointestinal problems.

Colonic Diseases, Functional↗
PubMed1982

[Treatment of chronic constipation with swelling substances].

In 20 patients with chronic constipation and, in many cases, years of laxative abuse, in a prospective and randomized study, treatment with new, specially prepared swelling substances administered at the recommended doses, was carried out after first stopping the use of laxatives. After only one week of this treatment, a marked increase in the weight of the stools, and a reduction in stool transit time (p less than 0.05 in each case) were observed.

Adult↗
PubMed1981

[Differential diagnosis of colitis].

The differential diagnostic possibilities in colitic changes are presented. In addition, the specific objectives of major examination procedures in the differentiation of the underlying diseases are indicated. In this connection, mention is also made of the etiopathogenic factors-in those conditions in which they are known with certainty.

Amebiasis↗
PubMed1981

Ten years of colonoscopy.

Over the last 10 years, 6170 colonoscopies have been performed at the Medical Department of the University of Erlangen. On the basis of these examinations, an overview, largely tabular in form, of the developments in the endoscopy of the lower gastrointestinal tract is presented. An assessment of the individual results obtained has intentionally not been undertaken. Present possibilities and requirements are presented by the diagnostic and therapeutic tasks and the solutions thus far employed.

Adult↗
PubMed1981

[Small bowel disease--an internal medical view (author's transl)].

Diseases of the small intestine are occurring rarely in the average number of hospitalised patients, thus diagnosis and therapy often are difficult. Therefore the following article gives an overview of the variety of these diseases. Clinical, diagnostical, and therapeutical possibilities are taken into special consideration. Malabsorption syndromes, gastroenteropathies with loss of proteins, enteritic diseases, tumors and anomalies of the small intestine are discussed.

Biopsy↗
PubMed1980

The healing process of experimentally produced bleeding lesions after hemostatic electrocoagulation with simultaneous instillation of water.

Fifty experimentally induced, standardized gastric bleeding lesions were successfully arrested in the dog using electrocoagulation with simultaneous instillation of water (EHT-coagulation). The contact pressure of the coagulating electrode was kept almost constant by means of a spring mechanism. The coagulated lesions healed without secondary enlargement of the coagulation effect and without complication. No secondary perforations were observed. Even when coagulation was carried out at an output power about 30% higher than the mimimum power necessary for reliable hemostatic coagulation, no complications were observed. Only with additional post bleeding arrest coagulation in excess of 10 seconds at this higher output, were two primary performations produced in 2 out of 12 cases. The non-perforated remaining 10 lesions healed without complication. With additional coagulation (at power output setting 6 for 20 seconds - 8 cases; at power setting 7 for 10 seconds - 6 cases), no perforations were observed and healing was without complications. Thus, in animal experiments, the therapeutic range for the arrest of bleeding using the electro-hydro-thermo-electrode is adequately large. The technique should be tested in clinical trials.

Animals↗
PubMed1979

[Developments in the diagnosis of colorectal carcinoma. Comparison of various diagnostic groups].

Epidemiological observations on colorectal cancer and the consequences of modern diagnostic methods are reported on patients treated in the Medical and Surgical Hospital of the University of Erlangen during the past 9 years. In this period the distribution of the rectal carcinomas according to the Dukes-classification was constant. Using coloscopy consequently as routine method and by proving occult intestinal bleeding as screening method, we succeeded in diagnosing colorectal carcinomas in an earlier stage of Dukes' classification.

Colonic Neoplasms↗
PubMed1979

Modified electrocoagulation and its possibilities in the control of gastrointestinal bleeding.

In acute experiments in the stomach of dogs electrocoagulation with simultaneous instillation of water (EHT-electrode i.e. electro-hydro-thermo-electrode) proved the most effective electrocoagulation method for controlling standardized bleeding: Optimal visibility at the bleeding site, extension of the therapeutic range as well as the avoidance of charring at the bleeding site are its major advantages. Disturbing adhesion of coagulated material on the electrode is also avoided. The electro-hydro-thermo-electrode is a cheap and portable means of controlling bleeding.

Animals↗