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Biomedical subjects

W M Thomas

Publications and source records attributed to W M Thomas.

47 records · Page 3Linked to original sources
PubMed1989

Role of dietary restriction in Haemoccult screening for colorectal cancer.

The aim of this study was to investigate the effect of dietary restrictions on the positivity rate and yield of neoplasia during a study based on Haemoccult screening for colorectal neoplasia. Of 18,925 participants who completed Haemoccult tests on a normal diet, 647 (3.4 per cent) were positive. All repeated the test with dietary restrictions: 251 remained positive and underwent further investigations which revealed 35 carcinomas and 169 adenomas in 129 subjects. The remaining 396 were sent a further Haemoccult test at 3 months. Of these, 317 (80.1 per cent) completed the test: 31 (9.8 per cent) were positive. Further investigation of the 31 positive subjects revealed four carcinomas and 20 adenomas. Retesting with dietary restriction will reduce the false positive rate of Haemoccult when used for colonic cancer screening. However, if the retest is negative a further test should be performed. To minimize the adverse effect this may have on compliance, we have allowed an interval of 3 months to elapse before this retest is requested.

Adenoma↗
PubMed1989

The use of magnets to move molars distally.

Repelling magnets, which were anchored to a modified Nance appliance cemented on the first premolars, were activated against the maxillary first molars to move them distally. Eighty percent of the space created represented distal movement of the first molars.

Adolescent↗
PubMed1989

Screening an asymptomatic population for colorectal cancer.

The best prospect of realizing a reduction in mortality from colorectal cancer appears to be by presymptomatic detection in a screened population. Presently, the only feasible method of mass population screening is by the detection of faecal occult blood and it is encouraging that all the major trials demonstrate that asymptomatic malignancy may be detected in this way. Furthermore, the screen-detected cancers are generally at an earlier pathological stage than those appearing in control populations. However, a note of caution is required. At the present time it is too early to demonstrate a reduction in mortality from the disease and there is evidence of a length bias, with more of the screen-detected cancers being well differentiated. The results of the large controlled trials will enable the benefits of screening to be viewed objectively and a recommendation for, or against, screening to be made.

Colonoscopy↗
PubMed1976

Hypertrophic colonic tuberculosis.

A patient who has suffered from hypertrophic colonic tuberculosis caused by the human strain of tubercule bacillus is presented. Despite being an uncommon presentation of tuberculosis, it is of more than academic interest to surgeons practising in tropical countries.

Colonic Diseases↗
PubMedDate not supplied

[Asymmetrical distalization of upper molars with magnets. A clinical case].

The treatment of a patient with an asymmetric malocclusion (class II, division I--subdivision) was presented. The treatment involved the use of repelling magnets for the distalization of the upper right molar which was in a class II relationship. A fixed "Nance" appliance attached to the second premolars was used for anchorage. Magnets are relatively easy to insert, are well tolerated, and they can distalize molars rapidly without significant loss of anchorage. No cooperation was required during the distalization phase of treatment and the second premolar distalized spontaneously once the "Nance" appliance was removed.

Adolescent↗