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Biomedical subjects

W M Ringsdorf

Publications and source records attributed to W M Ringsdorf.

At least 19 recordsLinked to original sources
PubMed1982

Vitamin C and human wound healing.

Clinical studies provide evidence that wound healing in subjects judged not deficient in vitamin C can be significantly accelerated with supplements of this nutrient above the recommended daily allowance (RDA). The authors administered daily dosages of 500 to 3,000 mg., which is roughly 8 to 50 times the RDA of 60 mg., to subjects recovering from surgery, other injuries, decubital ulcers, and leg ulcers induced by hemolytic anemia. Genetic impairment of collagen synthesis has also been observed to be responsive to ascorbic acid supplementation in an 8-year-old boy with Type VI Ehlers-Danlos syndrome. Four grams of ascorbic acid daily produced a significant improvement in the quality of newly synthesized collagen but did not alter that formed prior to the supplementation of C. The combined evidence in this review provides a substantial base for further research, both clinical and experimental trials, concerning the interrelationships between vitamin C and the body's healing potential.

Adult↗
PubMed1982

Predictive dentistry: a study in carbohydrate metabolism.

The virtues of prediction in the so-called health sciences are well-known. There is still small but burgeoning interest in predictive medicine; little has been done in predictive dentistry. The evidence presented in this report suggests that carbohydrate metabolism may be utilized as a predictive instrument in dentistry. While the emphasis in this document rests on biochemical techniques, there are other avenues, physiologic ones, such as photomotogrammetry, which can also be used. It is hoped that these paradigms will catalyze interest in this fascinating subject and generate research by others along these lines.

Blood Glucose↗
PubMed1982

Tissue tolerance to orthodontic banding. A study in carbohydrate metabolism.

Tissue tolerance to orthodontic banding was determined in a group of children in the Department of Orthodontics at the University of Alabama School of Dentistry. Nonfasting blood glucose and three oral parameters--gingival state, clinical tooth mobility and labial debris--were determined before banding a mandibular lateral incisor and again one month later. Each subject received a multivitamin-trace mineral supplement or an indistinguishable placebo during that month. In the placebo group, statistically significant blood glucose variability (variance) was found in those whose periodontal state was made worse by the orthodontic band. However, a very homeostatic pattern of blood glucose values was displayed by those whose gingival state, tooth mobility, and labial debris improved or remained the same in the presence of the band. Thus, blood glucose variability or homeostasis is one possible way to predict or measure the elusive factor that has been called tissue tolerance.

Blood Glucose↗
PubMed1981

Nutritional aspects of urolithiasis.

Although there is much concern about the relationship between vitamin C consumption and oxalate or uric acid lithiasis in the urinary tract, there is no controlled clinical study that demonstrates this occurrence. Equal concern should be accorded the other nutritional links to urinary lithiasis, since it is very unlikely that vitamin C or any one of the other factors is ever the sole cause of a kidney stone. The rare persons who, because of an altered metabolism, convert much of the ingested vitamin C into oxalic acid constitute the only high-risk category. If the other known nutritional variables were also investigated in these metabolically crippled persons, it might be possible to reduce or eliminate their risk from the intake of vitamin C.

Adult↗