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Biomedical subjects

W M Marks

Publications and source records attributed to W M Marks.

36 records · Page 2Linked to original sources

Intestinal pseudotumors: a problem in abdominal computed tomography solved by directed techniques.

Differentiation of normal bowel loops from pathologic process by computed tomography is often difficult. Techniques are described for opacification of bowel loops via oral, rectal, and colostomy administration of contrast material. Examples of abdominal and pelvic pseudotumors which were proven not to be pathologic lesions are presented. By following simple techniques of bowel marking, one can avoid false positive diagnoses.

Abdominal Neoplasms↗

Ultrasonic demonstration of endometrial fluid collections unassociated with pregnancy.

Intrauterine fluid collections were demonstrated by ultrasound in 17 non-pregnant patients. In nearly all instances, the surrounding echoes were of low to moderate amplitude. This has been noted previously in women with an ectopic or abnormal intrauterine pregnancy. In 2 patients, a well-defined thick rind of high-amplitude echoes encompassed the fluid, simulating an early gestational sac. Small intrauterine fluid collections were seen most frequently in non-pregnant patients who had vaginal bleeding or inflammation of the endometrium or adnexa.

Abscess↗

Ultrasonic evaluation of normal pancreatic echogenicity and its relationship to fat deposition.

Normal pancreatic ultrasound studies of 28 patients were evaluated as to pancreatic echogenicity and correlated with the morphologic appearance of the pancreas on CT to test the hypothesis that increasing pancreatic echogenicity is related to greater fat infiltration. Statistical analysis indicates that fat is a major but not the only determining factor of increasing echogenicity.

Adipose Tissue↗

Traumatic dislocation of the atlanto-occipital articulation (AOA) with short-term survival. With a radiographic method of measuring the AOA.

Three patients with traumatic atlanto-occipital articulation (AOA) dislocation are presented, and an additional 10 well documented cases are reviewed from the literature. Medulla oblongata and/or spinal cord deficits, and evidence of cranial nerve injuries were noted in eight patients. Angiographic evidence of vertebral occlusion or narrowing was demonstrated in four patients. One patient had systemic hypertension, presumably from bilateral traumatic ninth nerve injuries. Five patients ultimately died. A new method of measuring the AOA is introduced.

Adolescent↗

Computerized tomography in the quantitative assessment of tumour response.

While Computerized Tomographic (CT) scans have been a valuable asset to radiotherapy treatment planning, their role in the critical assessment of tumour response has been less well defined. Recent refinements in radiotherapy treatment techniques have intensified the need for non-invasive methods to evaluate the local control of inaccessible neoplasms. In this study, 20 cases in which both pre- and post-treatment CT scans were available up to 27 months post-therapy were reviewed. The majority of the patients had pancreatic carcinoma. In both pre- and post-therapy scans, the tumour volume was calculated from contours outlined on sequential CT slices. These interpretations were compared with surgical findings, clinical course and patient survival. The rate of the primary tumour regression had little bearing on the clinical outcome. However, there was CT scan evidence of initial local tumour stabilization or regression in > 80% of the cases. In addition, CT scan evidence of tumour progression was correlated with clinical progression in > 90% of the patients. This suggests that a growth delay analysis might be possible with the use of CT scans, at least for the evaluation of pancreatic carcinoma.

Humans↗

Pheochromocytoma of the broad ligament. Localization by computerized tomography and ultrasonography.

Computerized tomography (CT) and ultrasonography demonstrated a pheochromocytoma of the broad ligament of the uterus in a patient in whom arteriographic findings had been negative. We suggest that either or both of these techniques be used initially because, although they are not histologically specific, they are noninvasive and sensitive. An additional advantage of CT is its ability to evaluate sites of extra-adrenal pheochromocytomas above the diaphragm.

Adnexa Uteri↗

Computed tomography in the evaluation of patients with surgical clips.

Computed body tomography has proved to be a useful imaging modality in the follow-up study of patients with known malignant conditions undergoing therapy. While technologic improvements have made the number of artifacts few in number, a significant problem still exists from the streak artifacts emanating from surgical clips which degrade the image.

Adult↗

Computed tomography and ultrasonography in the evaluation of the retroperitoneum in patients with malignant ascites.

The computed tomographic (CT) body scans of 59 patients and ultrasonograms of 31 patients, all with malignant disease, were reviewed to determine the effect of ascites on the ability to image the retroperitoneum. In 95% of cases evaluated by CT, the retroperitoneal structures were well seen. In 35% of the cases evaluated by ultrasonography, the retroperitoneum was completely obscured by bowel gas and partially obscured in an additional 55%. As a result of this study, it is felt that CT should be the procedure of choice when a thorough evaluation of the retroperitoneum is necessary in patients with large amounts of abdominal ascites.

Ascites↗

The decidual cast of ectopic pregnancy: a confusing ultrasonographic appearance.

The appearance of the central uterine cavity was analyzed in 39 cases of ectopic pregnancy. In nearly 20% of cases, a fluid collection surrounded by an echogenic ring was present which could be mistaken for a normal early intrauterine pregnancy. When ectopic pregnancy is suspected clinically, and there is fluid in the cul-de-sac or an adnexal mass on ultrasound, a fetal pole should be evident within the central fluid collection before a definitive diagnosis of intrauterine pregnancy is made.

Decidua↗

Iodine absorption from the gastrointestinal tract during hypaque-enema examination.

Iodinated contrast agents administered intravenously or intra-arterially may cause serious reactions in hypersensitive patients. Oral administration of Hypaque (diatrizoate sodium) results in minimal absorption of iodine, but the amount of iodine absorbed with Hypaque-enema studies is unreported. Hypaque-enema examinations were performed in 20 normal, nonsensitive patients and increased serum iodine levels ten to 200 times base-line values, peaking after approximately one hour in patients who had measurements obtained for four hours. Therefore, before Hypague-enema studies, patients must be carefully questioned about their tolerance of iodinated contrast agents, and preparations should be made for possible serious hypersensitivity reactions.

Adult↗

Hepatocellular carcinoma: clinical and angiographic findings and predictability for surgical resection.

Demographic, clinical, and angiographic data were reviewed for 63 consecutive patients with hepatocellular carcinoma. Angiography remains the critical examination in determining extent of disease and potential surgical cure. Angiographic findings were correlated with surgical or autopsy findings for 26 of the patients. The absence of venous invasion and lack of involvement of at least one hepatic segment favor resectability. Selective hepatic injections and oblique views accurately answered these questions in more than 80% of our patients. Pitfalls to angiographic accuracy include vascular invasion by very small tumor masses, hypovascular or diffuse hepatocellular carcinomas, metastatic disease, and involvement of the left lobe.

Adult↗

Lymphomatous masses simulating cysts by ultrasonography.

Ultrasonography has proven to be extremely useful in the evaluation of lymphomatous masses within the abdomen and pelvis. However, these masses can at times appear extremely anechoic, exhibiting many features of fluid-filled or cystic masses.

Abdomen↗

CT diagnosis of tumor thrombosis of the renal vein and inferior vena cava.

Four cases of tumor thrombosis of the inferior vena cava and renal veins were diagnosed by computed tomography. In two, the thrombus itself was demonstrated within the vascular lumen after intravenous injection of urographic contrast material. The diagnosis was made in the other two patients by identification of massive enlargement of the vascular diameter.

Adrenal Gland Neoplasms↗