Search PubMed⌕ Search

Biomedical subjects

W M Dolmans

Publications and source records attributed to W M Dolmans.

10 recordsLinked to original sources
PubMed1990

Hepatitis B virus infection in patients with chronic liver disease and healthy controls in north-Sulawesi, Indonesia.

Markers of hepatitis-B virus (HBV) infection were determined in 42 patients with chronic liver disease (CLD) and in 42 age and sex matched healthy controls. At least one marker for HBV was found in 38 patients (90%) and in 29 controls (69%). HBsAg was present in 29 patients (69%) as opposed to 14 controls (33%; p less than 0.001). The very high prevalence of HBV infection, the significant difference with respect to HBV markers, particularly HBsAg, between patients and controls and in particular the high percentage of healthy HBV-carriers poses a considerable risk to the population of North-Sulawesi and stresses the need for HBV-vaccination.

Adult↗
PubMed1989

[Bladder schistosomiasis in school children; random study in the Ketu district, Ghana].

In 2 periods 1986/'87 and 1987/'88 1193 school children (5-19 years) from 13 randomly selected villages in the Ketu district, Ghana, were examined for Schistosoma haematobium (SH) in the urine. For the egg count the quantitative urine filtration technique was used and besides 3 indirect indicators of SH infection were evaluated. An arbitrary division was made into areas of high and low endemicity, showing SH prevalence rates of 54.3-23.0% and 2.3-16.0%, respectively. The condition of the "dams' in the different areas seemed to influence the infection rates. For all areas both prevalence and intensity of infection were both higher in boys than in girls. In the area of high endemicity it was possible to detect 99% of the heavily infected children (greater than or equal to 100 eggs/10 ml urine) by using the 3 indirect indicators combined.

Animals↗
PubMed1989

Prevalence of HIV-1 antibody among groups of patients and healthy subjects from a rural and urban population in the Mwanza region, Tanzania.

In April 1987, antibody to HIV-1 was determined in sera from 764 subjects from the Mwanza region in the north of Tanzania. Patients with a clinical suspicion of AIDS were HIV-1 antibody-positive in 65.4% (34 out of 52) and patients admitted for pulmonary tuberculosis in 25% (9 out of 36). In patients attending general outpatient departments (OPD), HIV antibody was found in 12.5% of 48 patients with a history of sexually transmitted disease (STD) and in 10.6% of 141 patients without such a history. In healthy subjects, HIV-1 antibody was present in 6% of 332 pregnant women and in 4.5% of 155 blood donors. Of the blood donors, pregnant women and OPD patients without a history of STD (628 subjects in all), 465 belonged to the rural population of the region and the majority were peasants. In this subgroup, the HIV-1 antibody prevalence was 4.8% in blood donors, 4.9% in pregnant women and 10.3% in OPD patients. This indicates a spread of HIV-1 among the population in this part of Tanzania. Further studies are needed to determine what proportion of the population is affected.

Adolescent↗
PubMed1989

Trypanosomiasis in a rural hospital in Tanzania. A retrospective study of its management and the results of treatment.

A retrospective analysis was done of the management and the results of treatment in 158 trypanosomiasis patients seen in a rural hospital in Tanzania during 1985. The distribution of cases in the population and during the year reflected an endemic situation. 109 patients (68.9%) were in the meningoencephalitic (ME) stage and 49 (31.1%) in the hematolymphatic (HL) stage of the disease. In total 19 patients (12.0%) died, 17 with ME and 2 with HL trypanosomiasis. Encephalopathy was seen in 19 (17.9%) of 106 patients treated with melarsoprol, and 10 of them died. In 15 (24.4%) of 64 patients who were discharged as HL trypanosomiasis evidence of CNS-involvement was found during follow-up after 3 and/or 9 months.

Animals↗