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Biomedical subjects

W M Dean

Publications and source records attributed to W M Dean.

3 recordsLinked to original sources

Amniotic fluid alpha-fetoprotein in fetal obstructive uropathy.

Amniotic fluid alpha-fetoprotein has been associated with various congenital anomalies. A diagnosis in utero of urinary obstruction associated with elevated alpha-fetoprotein is reported. Subsequent fulguration of type I posterior urethral valves was done. A possible mechanism for elevated alpha-fetoprotein with obstructive uropathy in utero is discussed. Pediatrics 66:537-539, 1980; alpha-fetoprotein, amniotic fluid, obstructive uropathy, posterior urethral valves, polyhydramnios.

Adult↗

Ammonium acid urate stones in Navajo Indian children.

Three Navajo children presented with a total of five upper tract acid urate stones. Although this stone is thought to be rare in the United States, it may be more common than is generally believed. Age, diet, environment, and in some instances urinary tract infection may be predisposing factors in the development of acid urate stones. Possible prophylactic measures are briefly discussed.

Child, Preschool↗

Spinal hematoma compressing cauda equina.

Epidural and subdural spinal hematomas are unusual complications of diagnostic lumbar punctures. A renal allograft recipient on anticoagulant therapy underwent lumbar puncture. Urinary retention and evidence of an S2, S3, and S4 neurologic deficit developed subsequently. A myelogram showed a defect of the posterior lumbosacral spinal canal. Urodynamic investigation demonstrated normal sympathetic innervation of the proximal urethra and impaired parasympathetic and pudendal innervation of the detrusor and external urethral sphincter, respectively.

Adult↗