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Biomedical subjects

W M Cole

Publications and source records attributed to W M Cole.

8 recordsLinked to original sources
PubMed1986

Influence of the lactoperoxidase system on susceptibility of the udder to Streptococcus uberis infection.

Lactoperoxidase (LP), thiocyanate (SCN-), pH and somatic cell counts (SCC) were measured in mammary secretions from 20 cows collected 14 d before drying-off, 7 and 21 d after drying-off, and 3-18 d postcalving. The inhibitory activity of the secretions on Streptococcus uberis was determined and the susceptibility of the udder to infection by this organism was tested by intramammary infusion of 250 colony forming units at the above stages. LP, SCN-, pH and SCC increased during involution and fell postcalving. The secretions collected before drying-off, 7 d after drying-off and postcalving inhibited growth of Str. uberis.; those collected 21 d after drying-off did not. Inhibitory activity in pre-drying-off secretions was destroyed by heating and restored by addition of LP, glucose and glucose oxidase, but addition of these substances to secretion 21 d after drying-off did not provide a full inhibitory system. The growth of Str. uberis in the secretions was correlated with intramammary susceptibility, since challenges with Str. uberis at 14 d before drying-off, at 7 and 21 d after drying-off and postcalving led to 43.8, 25.0, 81.3 and 37.5% of quarters becoming infected. It is suggested that the LP/SCN-/H2O2 system plays a role in protecting the lactating mammary gland from infection with Str. uberis but becomes ineffective as involution progresses.

Animals↗
PubMed1984

A note on the heterofermentative Lactobacillus isolated from kefir grains.

Heterofermentative lactobacilli have been isolated from kefir grains obtained from four different sources. A number of these isolates ferment only L-arabinose and gluconate and are similar to the species 'Lactobacillus desidiosus'. The DNA of these isolates, however, have 85-109% homology with 'L. caucasicus' NCDO 190 which is now regarded as L. kefir. The relationship between these strains is discussed.

Animals↗
PubMed1977

Classification and coding of psychosocial problems in family medicine.

Disease and problem classification systems for primary care have recognized that psychosocial problems are integrally related to more traditional medical problems which patients present to physicians. These classification systems remain inadequate for the description of primary care problems, especially as several disciplines interrelate in primary care, such as medicine, nursing, and social work. This paper presents a classification and coding system of psychosocial problems gleaned from a number of existing coding systems. The purpose of presenting it here is to contribute to a dialogue which will result in the establishment of a common psychosocial language for all health professionals. By so doing, progress in research, education, patient care, and administration in the psychosocial area will be facilitated.

Family Practice↗
PubMed1976

Social work fees in medical care: a review of the literature and report of a survey.

This paper is based on a study undertaken to determine the advisability of establishing fees for social work service in a Family Practice Residency Program as a way of providing a funding base to assure continuing this professional service in the model Family Practice Unit at the University of Washington; and as a way of providing social worker services in other medical clinics.

Family Practice↗