Search PubMedSearch

Biomedical subjects

W M Cocke

Publications and source records attributed to W M Cocke.

At least 19 recordsLinked to original sources

Radial composite chondrocutaneous flap for ear reconstruction.

Moderate sized cancers of the upper third of the ear can be widely excised, including cartilage, leaving the posterior skin intact. This avoids a large wedge excision and primary closure which leaves a significant defect. The unsupported soft tissue of the upper ear following excision of the cancer can be reconstructed by rotating into position a composite flap of skin and cartilage from the middle third of the ear. This composite flap supports the superior helix. The tissue defects of the flap donor site and the area superior to the flap inset can be closed with thick split grafts from the post-auricular area.

Cartilage

A critical review of augmentation mammoplasty with saline-filled prostheses.

This report analyzes the results of augmentation mammoplasty using saline implants. Follow-ups ranged from 18 months to 13 years. Of the 75 patients in this review, 39 had one or more problems, after the initial surgery, that detracted from a good or excellent result. Forty-two patients needed different volumes of saline to balance asymmetry of the breasts. Fourteen patients who preoperatively were thought to have normal breasts had breast pathology shown by biopsy at the time of surgery. Sixty-seven of the 75 patients eventually had excellent or good results, but 22 patients needed more than the initial operation to achieve this.

Adolescent

Malignant fibrous histiocytoma developing in burn scar of the ear.

Malignant fibrous histiocytoma is the most common soft tissue sarcoma. The tumours usually present as a painless enlarging mass deep to the subcutaneous tissue most often in the thigh. Wide excision is the recommended treatment, as the incidence of recurrence is high in patients with marginal excision. Metastases can occur in 50 per cent of patients. This patient represents a rare and previously unreported presentation of malignant fibrous histiocytoma in a burn scar of the ear.

Aged

Secondary reconstruction of abdominal wall defects associated with exstrophy of the bladder.

Exstrophy of the bladder is a spectrum of congenital anomalies that involve the structures of the lower abdominal wall. The classic bladder exstrophy results in a severe deformity. The purpose of the original surgery is to obtain a secure abdominal wall closure with urinary continence. In present times the abdominal wall is repaired shortly after birth. The occasional patient has residual anatomical deformities that impede their social development and interaction. Secondary reconstructive surgery can be helpful, and this patient report illustrates this.

Abdominal Muscles

Observations of cell function and morphology in the presence of silicone gel: an in vitro study.

The project described in this article used in vitro tissue culture techniques and flow cytometry to determine if there are alterations in cell morphology in those cells that have been placed in contact with a commercially available medical-grade silicone gel used in mammary implants. We were unable to demonstrate significant changes in cell cycle characteristics following in vitro exposure for 1 to 12 days using human fibroblasts, mouse fibroblasts, and Chinese hamster ovary cells.

Animals

Calcified capsule following augmentation mammaplasty.

Five patients who developed calcification of the capsule following augmentation mammaplasty are described. This long-term complication may be encountered with increasing frequency and should be considered in evaluating women with solid, firm, constructed capsules.

Adult

Panniculectomy and the difficult ileostomy for urinary diversion.

This paper describes a helpful operation for revision of the difficult ileal stoma for urinary diversion. By using the standard technique of panniculectomy or abdominal lipectomy, the ileal loop can be left in the same position on the abdominal wall and healthy, viable tissue can be mobilized and repositioned to enable the urological surgeon to perform the cutaneous portion of the procedure again and to refashion the ileal loop. This saves the patient an operation of greater magnitude and risk.

Abdominal Muscles

Cutaneous pseudolymphoma.

The diagnosis of cutaneous lymphoreticular infiltrative lesions is difficult. There are many diagnoses possible, and oftentimes it is difficult to distinguish between a malignant lymphoma cutis and any of the many benign lymphomas. This article deals with a patient who was diagnosed as having metastatic small-cell carcinoma. Because of the inconsistency between the pathologic diagnosis of malignancy and the benign clinical findings and course, a wide ablative excision of the lesion was done and the surgical specimen was studied thoroughly by numerous pathologists. Even then the diagnosis could not be clearly established. The differential diagnosis of cutaneous lymphomatoses is discussed.

Carcinoma