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Biomedical subjects

W M Christopherson

Publications and source records attributed to W M Christopherson.

72 records · Page 4Linked to original sources
PubMedDate not supplied

Relation of steroids to liver oncogenesis.

Experience with pathological material from 150 women with liver tumors is reviewed. The features of liver cell adenoma and focal nodular hyperplasia are sufficiently different that the vast majority of the benign tumors can be easily subclassified. Although most occurred in women ingesting steroids, the wide usage of oral contraceptives makes it difficult to prove a causative role. Nineteen of the tumors were malignant and, to date, 12 of those patients have died of their disease. Since hepatomas are much more common than benign liver tumors, one must be even more circumspect in indicting steroids in their causation. In this group of women none had cirrhosis, whereas in the general population cirrhosis is a very common precedent lesion. Further investigation of estrogens and primary liver carcinoma would be timely.

Adolescent↗
PubMedDate not supplied

Trends in mortality from uterine cancer in relation to mass screening.

Mortality rates from cancer of the cervix uteri, as well as for all uterine cancer, have shown a remarkable decrease in recent years in Louisville, Kentucky. For women ages 30-39 the decrease was 70.8 per cent, and for ages 50-59, 69 per cent. No change in rates was noted for women ages 70 years and over. These changes correlate well with the success of recruitment for screening of women according to age. The high degree of success in screening the low socioeconomic quartile is thought to be of prime importance. The average annual age adjusted mortality for uterine cancer other than cervix also fell impressively. In contrast to Louisville, mortality from cervical cancer in England and Wales, with the exception of the younger age group, has remained fairly constant over the past decade. Denmark showed no mortality decline between 1961 and 1971. Like England and Wales and unlike Louisville, screening there had not achieved high population coverage and the screening as does exist was not commenced as early.

Adult↗
PubMedDate not supplied

Growing pains.

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Certification↗