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Biomedical subjects

W M Carpenter

Publications and source records attributed to W M Carpenter.

At least 37 records · Page 2Linked to original sources

The prevalence of recurrent herpes labialis during an army hot weather exercise.

A survey was performed on 1,062 of 2,500 (42%) Army personnel participating in a desert training exercise at Fort Irwin, California, in September 1983. The prevalence of recurrent herpes labialis (RHL) and chapped lips was observed during the third week of a four-week training period. Complexion, sex, lip protectant use, age, and time spent outdoors were obtained by observation and interview. Recurrent herpes labialis was found in 46 subjects (4%). Stratified analysis and stepwise logistic regression were used to identify risk factors associated with RHL and to determine the prevalence odds ratios (POR). Risk factors with statistically significant associations with RHL were lip protectant use (POR = 0.19), chapped lips (POR = 2.87), being female (POR = 5.00), and light complexion (POR = 2.48). These findings strongly support the use of lip protectants during prolonged exposure to hot, dry climates as a prophylaxis against recurrent herpes labialis. Additional studies should focus on excitatory factors of RHL; and clinical trials of the efficacy of the lip protectants to protect against RHL and chapped lips should be undertaken.

Adolescent↗

Adenomatoid hyperplasia of minor salivary glands.

Adenomatoid hyperplasia of minor salivary glands is an uncommon clinicopathologic entity. It comprises clinical swelling resembling a neoplasm with a histologic picture of aggregates of normal-appearing salivary gland tissue in excess of that anticipated for the anatomic site. The significance of this lesion is derived from its clinical resemblance to a neoplasm of salivary gland origin. This study adds 40 new cases to the literature and analyzes their clinical and histologic features. Most of the lesions were located on the hard and soft palates. The exact nature of the minor salivary gland hyperplasia is not clear. Some of the cases may represent a hamartoma or a reactive hyperplasia, but in most cases the nature of the hyperplasia is idiopathic.

Adolescent↗

Anterior lingual mandibular salivary gland defect. Evaluation of twenty-four cases.

Lingual mandibular salivary gland defects in the posterior part of the mandible are not uncommon. Analogous defects in the anterior region, however, are rare, and the four new cases presented in this report bring the total number of reported cases up to 24. The purpose of the present study was to review and analyze the clinical, radiographic, and histologic features of the previously reported cases together with those of the present study. The majority of these defects were located in the cuspid and/or premolar area and were diagnosed in men in their fifth and sixth decades of life. Almost all defects contained normal salivary gland tissue. The differential diagnosis, treatment, and pathogenesis of these defects are discussed.

Adult↗

Complex facial radicular groove in a maxillary lateral incisor.

A case report of a developmental anomaly known as a radicular groove is presented. This case is unusual in that it is believed to be the first reported case of complex involvement of the entire facial aspect of a tooth root. An alveolar crest to apex facial root defect in a maxillary right lateral incisor of a 12-yr-old black female led to early pulpal necrosis and periapical rarefaction. Clinical and histologic findings as well as morphologic and treatment ramifications are discussed.

Child↗

Central (intraosseous) calcifying odontogenic cyst.

The central calcifying odontogenic cyst (CCOC) is an uncommon lesion. The present study reports 17 new cases of CCOC and analyses their clinical and histomorphologic features. The data revealed that CCOC were usually diagnosed in the second decade of life with an almost equal distribution between the maxilla and the mandible. Six of the 17 cases (35%) were associated with odontomas and 6 lesions (35%) were associated with unerupted teeth. Histologically, most of the lesions were unilocular cysts but at least one was multilocular and one was a mixed lesion - partially cystic and partially solid. Excision with long-term follow-up (up to 10 years) is the treatment of choice.

Adolescent↗

Melanocytic nevi of the oral mucosa: a clinicopathologic study of 130 cases from northern California.

This paper presents analysis of data on 130 cases of oral melanocytic nevi from the files of the University of the Pacific, San Francisco and the University of California, San Francisco. This is the largest detailed series from one geographic location published to date. Nevi of the intramucosal type are the most common (63%) followed by the common blue nevus (19%). Compound nevi are uncommon (9%) and junctional nevi are rare (5%). Combined nevi are the rarest type (4%). The data are analyzed as to the location, presence of clinical pigmentation, configuration, and size of the nevi, as well as the patient's age, gender and race. Because the malignant potential of oral nevi is still uncertain and because preexisting macular pigmentation is present in about one third of all patients with oral melanoma, it is advisable to remove all pigmented lesions suspected to be melanocytic nevi.

Adolescent↗

Oral intravascular papillary endothelial hyperplasia.

Intravascular papillary endothelial hyperplasia (IPEH) is usually a cutaneous lesion thought to represent a peculiar manifestation of an organizing thrombus. IPEH can be subdivided into a pure form that occurs within a dilated vascular space and a mixed form that appears as a focal change within a preexisting vascular lesion, such as hemangioma. The principle significance of the lesion lies in the fact that it may be mistaken for angiosarcoma. Oral lesions are uncommon and the present paper reports on 16 new cases of oral IPEH, analyzing their clinical and histomorphologic features. Histologically, 11 lesions appeared in a pure form and 5 lesions in a mixed form. Thrombi were detected in all but one case. The most common location was the lip, followed in decreasing frequency by the tongue and buccal mucosa. Local excision was the treatment of choice.

Adult↗

Gingival cyst of the adult. Case report of a bilateral presentation.

The gingival cyst of the adult (GCA) constitutes a pathologic developmental process that the dentist must be prepared to diagnose and treat. The GCA has been infrequently reported in the past as a unilateral phenomenon, but this case constitutes the first known report of synchronously occurring, bilateral GCA in the dental literature.

Gingival Diseases↗

Radicular evaginatus--a root anomaly.

An unusual root malformation in a mandibular second premolar is presented. Clinical and histologic findings, as well as treatment ramifications, are discussed. The pathogenesis of this malformation is also discussed. The term radicular evaginatus is suggested for this condition.

Adult↗

The mucocutaneous marker of pseudoxanthoma elasticum.

A patient with angioid streaks discovered ophthalmoscopically was evaluated in the dermatology clinic for pseudoxanthoma elasticum (PXE). Cutaneous markers for PXE did not appear in the usual locations; mucosal involvement of the lower lip was the only clinically ascertainable clue. The presence of the disease was confirmed by histologic examination of the oral mucosa. This case stresses the importance of familiarity with the mucocutaneous markers of PXE by members of the dental profession.

Humans↗

Clear-cell sarcoma of tendons and aponeuroses.

The natural history and histologic characteristics of a rare malignant neoplasm of tendons and aponeuroses are described, and a case is presented which originated in the right foot of a 19-year-old Caucasian woman who succumbed to the disease after 4 years. This case represents the first known example of metastasis to the oral cavity of this particular neoplasm.

Adult↗