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Biomedical subjects

W M Allen

Publications and source records attributed to W M Allen.

12 recordsLinked to original sources
PubMed1978

A field trial of 1alpha-hydroxycholecalciferol (1alpha-OH D3) in the prevention of milk fever.

The efficacy of 1alpha-OH cholecalciferol for the prevention of milk fever has been tested in a controlled field trial using 597 cows on 19 farms all of which had previously had a high incidence of milk fever. Of 293 cows receiving 1alpha-OH cholecalciferol 34 had milk fever and of 304 control cows 51 had milk fever. Although there was an apparent efficacy of 31 per cent the difference in incidence was not statistically significant. There was no effect if 1alpha-OH cholecalciferol was administered less than 24 hours before the cows succumbed to milk fever. However, if 1alpha-OH cholecalciferol was administered more than 24 hours and less than one week before the occurrence of milk fever the efficacy increased to 61 per cent and the effect was highly significant.

Animals↗
PubMed1976

Use of 1alpha-OH cholecalciferol in preventing post parturient hypocalcaemia and its potential value for the prevention of milk fever in dairy cows.

Cows which received 250 mug 1alpha-hydroxy cholecalciferol (1alpha-OH D3) intramuscularly within two hours after calving suffered significantly less post-parturinet hypocalcaemia and hypophosphataemia than control cows. There was a small depression in plasma magnesium concentrations in the treated cows. 1alpha-OH D3 shows potential for the prevention or treatment of milk fever.

Animals↗
PubMed1975

Asymmetric hindquarter syndrome (AHQS) in the pig.

Outbreaks of the asymmetric hindquarter syndrome (AHQS) in two pig herds are reported together with the results of test matings and dissection studies on affected pigs. The condition (apparently identical with that described in Germany in 1967), is characterised by a variable asymmetry of the hindquarters and particularly of individual muscles of the posterior, lateral and medial aspects of the thigh. It does not noticeably interfere with locomotion but can adversely affect carcase conformation and may detract from the usefulness of carcase dissection studies as a basis for genetic selection. AHQS has a familial incidence and is usually first detected clinically after weaning. A variety of degenerative and dystrophic changes have been seen in the muscles of AHQS pigs but these are not constantly present in nor confined to 'undersized' muscles. The precise aetiology of AHQS is still unresolved but it is concluded that it probably occurs post-natally and that some pigs have a genetic liability to develop the condition.

Animals↗