[Autologous transfusions of frozen blood in heart surgery].
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Biomedical subjects
Publications and source records attributed to W Luboldt.
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Children, young people and women at the age of possible maternity form the majority of patients operated by extracorporal circulation. A longterm planning of these operations should also have donor in call, who are compatible with the patients' Rh groups and Kell antigens. Having practiced such a selection of donors we succeeded in reducing the formation of immune antibodies. 6 out of 330 patients had antibodies, but 4 had been sensibilized before operation. In the case of the other 2 it would not be excluded that they might have been immunized a long time ago. We emphasize the importance of hemodilution, strict indication of every postoperative therapy with red cells and the autologous transfusion.
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With further improvements in multislice CT, enabling now the combination of lung and colon imaging within one breathhold with automated dose optimization, MR colonography has almost been given up. But similar to angiography, we are optimistic that MR can be compatible to CT in colonography and report in this article on the current status and perspective of MR colonography. For more information see www.multiorganscreening.org.
BACKGROUND: To evaluate the potential of magnetic resonance colonography (MRC) in detecting colorectal mass lesions. METHODS: Twenty patients underwent MR imaging (MRI) before colonoscopy. The colon was filled with a gadolinium (0.5 mol):water mixture (1:100) under MRI control, and patients were imaged while breath-holding imaged with a three-dimensional spoiled gradient echo sequence in the prone and supine positions. Images were interactively analyzed based on the combination of multiplanar reconstruction and virtual colonoscopy by a radiologist blinded to colonoscopic findings and the patient's history. MRC interpretations were correlated with colonoscopic results. RESULTS: Polyps smaller than 5 mm could not be identified with MRC. The sensitivity for detecting polyps of 5-10 mm was 70%, whereas mass lesions larger than 10 mm were all detected (sensitivity = 100). The sensitivity, specificity, and accuracy for identifying polyp-positive patients including the three patients with small (<5 mm) polyps were 64%, 89%, and 75%, respectively. CONCLUSION: Virtual colonoscopy based on MRI data is feasible and should be evaluated in a larger sample of patients.