[Nitrofurantoin in the treatment of vaginal trichomoniasis in women].
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Biomedical subjects
Publications and source records attributed to W Lotocki.
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Morphological methods, in particular histochemical technique of secondary fluorescence according to Bertalanffy were used for the assessment of regressive changes of placenta. In women with primary arterial hypertension during early pregnancy fibrinoid masses in decidua, chorion, anchoring willi, villous plate, basal plate, villous trunks and terminal villi appear. These changes are followed from one side, by an atrophy of the blood vessels and connective tissue cells, and from the other, there increases the number of decidua giant cells, as well as of syncytium and cytotrophoblast. The areas of impaired blood supply contain giant cells and intervening foam cells. These cells according to the authors can be the forms of regressive changes exhibiting relative biological activity influencing trophic status of the placenta. Possible importance of the fibrinoid masses for the immunology of pregnancy which is developing under maternal morbid conditions has been discussed.
Urodynamic measurements including sphincterometry and cystometry were made in 36 women with stress urinary incontinence (SUI). Out of this number in 32 affected with SUI of stages I, II and III surgical treatment was applied. Control group were 7 women without SUI symptoms. Marshall-Marchetti operation in the modification of Durfée or of Burch was made in the space of Retzius. The procedure was followed by simultaneous pararectal suturing of the wedges of levator ani muscle. The mean values of urodynamic measurements were compared using Student's "t" test and paired test. No evident difference was found when average values of pre-operative +cystic manometry were compared in particular groups of patients using statistical analysis. Sphincterometry made in women who had been effectively operated on showed statistically significant higher values of urethral closure pressure. Higher values of post-operative urodynamic measurements can speak for a complete recovery of the patients.
Post-operation results of stress urinary incontinence treatment have been assessed and subjected to statistical analysis in 667 patients. The elaboration of the results was based on case history data, inquiries and control ambulatory examinations. Diagnostic procedures included sphincterometry, cystometry, cystoscopy, cystography and provocation test like coughing. Vaginal and urine biocenosis was always assessed microbiologically. The Marshall-Marchetti operation as modified by Durfée and Burch was made within the space of Retzius. Complementary procedure consisted in suturing levator ani muscles after previous bilateral opening of pararectal space within perineum. Third pair of sutures was placed according to the authors' own modification during the Durfée operations. The results of surgical treatment of SUI performed by the authors do not differ in principle from those reported by others. A small number of relapses the authors ascribe to local and systemic processes of aging which diminish the effectiveness and the value of previously made correction of urethra and of the bladder bottom topography.
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