Biomedical subjects

W Liu

Publications and source records attributed to W Liu.

At least 253 records · Page 14Linked to original sources

PubMed2001

An experimental study on drugs for improving blood circulation and removing blood stasis in treating mild chronic hepatic damage.

Large and small doses of drugs for improving blood circulation and removing blood stasis were used in model rats to treat mild chronic hepatic damage induced by carbon tetrachloride (CCl4). The results show that large dose of Dang Gui ([symbol: see text] Radix Angelicae Sinensis) and Dan Shen ([symbol: see text] Radix Salviae Miltiorrhizae) (drugs for regulating blood flow) and small dose of Yu Jin ([symbol: see text] Radix Curcumae) and Niu Xi ([symbol: see text] Radix Achyranthis Bidentatae) (drugs for activating blood flow) can significantly elevate the activity of SOD (P < 0.05) and/or lower the T/K ratio, markedly reduce the MDA content (P < 0.05 or P < 0.01) and significantly decrease the activities of ALT and AST (P < 0.05 or P < 0.01), demonstrating that these drugs are effective in combating oxygen free radicals (OFR) in chronic liver damage. On the contrary, large dose of Tu Bie Chong ([symbol: see text] Eupolyphaga seu Steleophaga) and E Zhu ([symbol: see text] Rhizoma Curcumae) (drugs for removing blood stasis) tend to increase the ALT and AST (P < 0.05) activities. The results suggest that the synergism of elevation of the SOD activity and reduction of T/K ratio contributes to the action of drugs for improving blood circulation and removing blood stasis in combating the liver damage induced by CCl4.

Alanine Transaminase↗

PubMed2001

[GC-MS analysis of volatile oil from Atractylodes chinensis].

OBJECTIVE: To determine chemical constituents of volatile oil from Atractylodes chinensis(D. C.) Koidz by quantitative with qualitative analysis. METHODS: By GC and GC/MS/DS analytical technology and SE-54 capillary column, the chemical constituents of volatile oil from Atractylodes chinensis(D. C.) Kiodz were systematically analyzed. RESULTS: 68 peaks were separated, which occupied over 90% of the total area of all chromatographic peaks. The 55 components were identified. CONCLUSION: The number of compoments of volatile oil from Atractylodes chinensis(D. C.) Koidz determined in this analysis, are two times as many as those reported in some literatures.

Asteraceae↗

PubMed2001

Performance modeling of subsurface-flow constructed wetlands systems.

A subsurface flow constructed wetlands (CW) system, located at a neighborhood consisting of a small housing development and golf courses outside of Lincoln, NE, was studied for its effectiveness as a small community wastewater system. Extensive monitoring was conducted biweekly between June 1996 and December 2000. Prediction models for soluble CBOD5 NH3-N, and TP removal in CW were employed for comparison with the field data. It was found that the disappearance of BOD5 and NH3-N could be approximated using first-order kinetics, but the kinetics of TP removal were unclear. The reduction rate constants regressed from the field data were found to be lower than literature reported values.

Ecosystem↗

PubMed2001

[The surgical treatment for cerebellopontine angle meningioma].

OBJECTIVE: To discuss the risks and benefits of the surgical treatment for cerebellopontine angle meningioma. METHODS: Eighty-eight patients with cerebellopontine angle meningioma treated surgically in the last twenty years were analyzed retrospectively. All patients were followed up from six months to eleven years. RESULTS: Complete resection was done in 68 (77.3%) patients and subtotal resection in the rest 20 patients. Six(6.8%) patients died after the operation. Follow up showed that eight (13.3%) patients died and six (10%) patients developed recurrence. CONCLUSION: Surgery is the treatment of choice for cerebellopontine angle meningioma. It is the key to rationally choose the adequate approach, carefully manage and protect the vessels, nerves, brain stem and to institute timely and rationally the auxiliary therapy for the postoperative complications in order to increase the efficacy and improve the patients' quality of life.

Adolescent↗

PubMed2001

[Ecological characteristics of phytoplankton in waters of biological-controlling and ordinary rice fields].

Through investigations from March to June 1998 on the phytoplankton in waters of biological-controlled and ordinary rice fields, 112 species of phytoplankton were found, of which, Bacillariophyta, Euglenophyta and Chlorophyta were dominant. The comparison of the species in two rice fields showed that in biological-controlled rice field, there were more species of Euglenophyta, with 5 most dominant species, i.e., 2 of Euglenophyta, 2 of Bacillariophyta and 1 of Chlorophyta. In ordinary rice field, there were more Bacillariophyta species, in which, 5 most dominant species belonged to Bacillariophyta, except Scenedesmus bijuga to Chlorophyta. The biodiversities of phytoplankton and their evennesses were also analyzed with the period from the seedlings being planted to the rice fields being dried, showing that a little increase in their biodiversity mainly caused by the increase of species number and an evident decrease in their evennesses.

Ecosystem↗

PubMed2001

[Clinical study of a new expander with an agent delivery system and the effect of a chemical agent on tissue expansion].

OBJECTIVE: To search for a method to enhance tissue expansion. METHOD: A new type of expander with an agent delivery system was used to expand soft tissue in 15 patients. During expansion Papaverine was delivered through the delivery system into the tissue around the expanders. RESULTS: It took 26 days to expand to the anticipated volume in the new expansion method group (NEM) and 51 days in the general expansion method group (GEM) (P < 0.01). Before operation the NEM group was over-expanded by 92.4% while the GEM group was over-expanded by 27.12%. At full expansion the blood flow of the expanded area of the two groups was 1.27 (NEM) and 0.64 (GEM). The immediate skin retraction of the two groups was 20.17% (NEM) and 38.26% (GEM). CONCLUSION: The new expansion method can accelerate expansion speed and improve the quality of expanded skin and flap.

Drug Delivery Systems↗

PubMed2001

[The investigation with contrast sensitivity after implantation with UV and UVCY types of intraocular lens].

OBJECTIVE: To research the difference in vision after UV and UVCY two types of intraocular lens implantation (The light 380-790 nm may transmit through the UV lens, and the UVCY lens may partly filter the light < 640 nm including part of the light < 460 nm.). METHODS: MCT 8000 contrast tester was used in the postoperative two months. RESULTS: The contrast sensitivity of the patients with UVCY lenses was superior to that with UV lenses obviously (P < 0.05) under the condition of glare and 3 c/d, 6 c/d space frequency. CONCLUSION: The UVCY lens is more advantageous to improve visual function.

Aged↗

PubMed2001

Human movement characteristics of target acquisition.

Objective. This paper deals with the problem of human movement characteristics of target acquisition. Method. A hypothetical model was posed by using experimental data. Result. The conception of final target size was put forward, an equation for calculating the movement time of target acquisition was obtained, and a new definition of index of difficulty was given. Conclusion. Analysis of experimental data showed that this equation could give a better description of target acquisition in a wide range.

Acceleration↗

PubMed2001

[Preparation of green fluorescent protein retrovirus and its application in mediating gene transfer into retinal pigment epithelial cells].

OBJECTIVE: To determine whether human retinal pigment epithelial (RPE) cells can be infected by retrovirus and modified by retrovirus-mediated gene transfer. METHODS: Recombination retroviral vector pLNCX-GFP (green fluorescent protein, GFP) was generated by inserting 780 bp GFP cDNA fragment into the MCS site of pLNCX. pLNCX-GFP was transfected into ecotropic packaging cell line PhiX-Eco and amphotropic packaging cell line PhiX-Ampho and PA317. Retroviral titer was tested by counting GFP expression of NIH3T3 cells. Then RPE cells were infected by using GFP retrovirus-containing supernatant. RESULTS: GFP was expressed and retrovirus was produced upon pLNCX-GFP being transfected into packaging cell line. The GFP retrovirus was able to infect primary cultured human RPE cells and immortalized RPE cell line. CONCLUSION: The retrovirus can introduce a foreign gene into RPE cells efficiently, thereby it can be used as an important tool to deliver gene into RPE for therapy of fundus diseases.

Cells, Cultured↗

PubMed2001

[The relationship of clinicopathology and immunophenotypes in non-Hodgkin's lymphomas of the spleen].

OBJECTIVE: To investigate the relationship between clinicopathologic features and immunophenotypes in non-Hodgkin's lymphoma (NHL) of the spleen. METHODS: Clinicopathologic analysis and follow up; immunohistologic staining by SP method and EBER in situ hybridization. RESULTS: (1) Splenomegaly was found in all 19 cases of spleen NHL, 10 of the 19 (52.6%) cases had masses or a mass in their enlarged spleen; (2) 14 of the 19 (73.7%) cases were of B-cell type (including 5 cases of follicular type and 9 cases of diffuse type), in which 8 cases were centroblastic, 3 of centroblast/centrocyte and 4 cases of small lymphocyte types; all 10 cases of primary splenic lymphomas (PSL) were B-cell type; (3) 5 of the 19 cases (26.3%) had peripheral T-cell origin, including 4 cases of large cell type and 1 case of small cell type; of the 3 TIA-1 positive cases, 2 were also positive for EBER 1/2 (one CD 8+ and another CD56+), the remaining case was CD8-, CD56-, EBER1/2-; all 5 cases were secondary NHL of the spleen; (4) Follow up data were obtained for 14/19 cases (73.7%). 8 of 9 surviving cases were primary NHL. The range of survival period varied from 8 to 10 years. All 5 deceased cases had secondary NHL and their survival period was 2 to 6 months. CONCLUSIONS: Some relationship exists between the clinicopathology and origin of the tumor cells in splenic NHL, the prognosis of primary NHL is better than that of the secondary NHL and the diagnosis of primary NHL should be made with discretion.

Adolescent↗

PubMed2001

[Cytotoxic natural killer/T-cell lymphomas of the lymph nodes].

OBJECTIVE: To investigate the clinicopathologic features of cytotoxic natural killer (NK)/T-cell lymphomas of the lymph nodes. METHODS: Clinicopathologic observations and follow up on 5 cases of cytotoxic NK/T-cell lymphomas of the lymph nodes, immunohistochemical staining for CD45RO, CD8, CD56, CD30, CD20, TIA-1 and in situ hybridization for EBER1/2 were performed. RESULTS: (1) The clinicopathologic features of cytotoxic NK-T-cell lymphomas of the lymph nodes were summarized; (2) The tumor cells were positive for CD45RO in 4 of the 5 cases, in which 3 cases were also positive for CD56. One case was of null cell type. The tumor cells were positive for TIA-1 and EBER1/2 in all 5 cases. CONCLUSIONS: The clinicopathological features and special immunophenotypes of cytotoxic NK/T-cell lymphomas of the lymph nodes were present in all 5 cases. Clinically, this entity tends to be an aggressive process with poor prognosis.

Adult↗

PubMed2001

[Suppression of glutamate neurotoxicity by 5-HT in hippocampal neurons].

The effects of excess glutamate on the survival rate of cultured hippocampal neurons, the population spike (PS) of CA1 area of hippocampal slices and the Ca(2+) current of hippocampal neurons were observed in rats. Decreased survival rate of hippocampal neurons in the presence of excess glutamate was partially reversed by 5-HT, which was in association with a less decrease of PS magnitudes. The Ca(2+) inward current induced by glutamate was significantly diminished in the presence of 5-HT. It is suggested that 5-HT can inhibit excess glutamate-induced neurotoxicity by suppressing the glutamate triggered calcium influx.

Animals↗

PubMed2001

[Comparative study on antibody levels of vaccination group and control group after 4 years of immunized with type B inactivated vaccine against hemorrhagic fever with renal syndrome].

OBJECTIVE: To compare the antibody level of vaccine group and control group in a randomized, controlled trial of type B inactivated vaccine against hemorrhagic fever with renal syndrome(HFRS) in Jiande County of Zhejiang Province and to find out if there is enhancement of subclinical infection about type B inactivated vaccine against HFRS. METHODS: The number of sera collected (July 1994-July 1998) in vaccine group immunized type B inactivated vaccine against HFRS and control group were 305 and 283 persons in Jiande County respectively, and indirect immunofluorescent antibody method(IFAT) was used for testing the titer of HFRS IgG in sera. The cut-off values were determined on IFA titer of the second sera in control group with positive and negative IFA before vaccine was given respectively, and the subclinical infection of positive and negative IFA of the first sera in vaccine group was evaluated. RESULTS: When taking different cut-off values of subclinical infection, there were no statistical differences in HFRS IFA positive rates between vaccine group and control group of positive IFA in the first sera. In vaccine group and control group of negative IFA before vaccine given, also the IFA positive rates were not statistically different in these groups. There were no statistical differences of IFA GMT and IFA sero-negative rate between vaccine group and control group. CONCLUSIONS: The investigation showed there was no statistical difference in antibody level between vaccine group and control group, so there could not be enhancement of subclinical infection of vaccine group receiving type B inactivated vaccine against HFRS.

Adolescent↗

PubMed2001

[Observation on the effect of GM-CSF and alpha-INF joint treatment on chronic hepatitis B].

OBJECTIVE: To observe the effect of GM-CSF and alpha-INF joint treatment on chronic hepatitis B. METHODS: GM-CSF treatment combined with alpha-INF was set up as experimental group and alpha-INF alone as the control. At the same time, we counted the blood leukocytes, monocytes and granulocytes of the patients. RESULTS: The short-term and long-term effective rates of the experimental group were 61% (11/18) and 67% (12/18) respectively, while those of the control group were 44% (8/18) and 33% (6/18) respectively. The leukocyte, monocyte and granulocyte counting in blood of patients treated with GM-CSF and alpha-INF increased significantly. CONCLUSION: GM-CSF and alpha-INF joint treatment is effective for chronic hepatitis B. The mechanism may be related with the increasing number of monocytes in blood, hence to improve the antigen delivering ability.

Adolescent↗

PubMed2001

[Evaluation of the effects of two operative option in the treatment of orbital fractures].

OBJECTIVE: In order to explore the treatment and it's clinical effects of orbital fractures. METHOD: 34 patients were separately treated with nasal endoscopic surgery and external nose incision surgery. RESULT: The total effective rate of nasal endoscopic surgery and external nose incision surgery was 90.0%, 91.6% respectively. There was no significant difference between the two groups (P > 0.05). CONCLUSION: Treating orbital fractures under nasal endoscopic surgery has advantages such as no incision on face, less damage, clear view and easy recheck after operation. It is the best way to treat this kind of disease.

Adolescent↗

PubMed2001

[Clinical comparison of bilateral neck dissection for supraglottic carcinoma].

OBJECTIVE: In order to rise the survival rate and quality of life, the patients with bilateral neck dissection was investigated in supraglottic carcinoma. METHOD: 76 cases were retrospectively analyzed. In terms of clinical diagnosis, 33 cases who had bilateral neck metastasis had received simultaneously bilateral neck dissection. 43 patients first diagnosed unilateral neck metastasis got subsequent bilateral neck dissection. All of the patients were pathologically diagnosed. RESULT: The 3 and 5 year survival rates, in the 33 cases who had received simultaneous bilateral neck dissection, were 81.5% (22/27) and 61.5%(16/26) respectively, while in the other 43 cases, was 69.2%(27/39) and 27.8%(10/36) respectively. CONCLUSION: It is necessary for those patients who have suffered from supraglottic carcinoma with bilateral neck metastasis to have simultaneous bilateral neck dissections. Meanwhile, the preservation of bilateral internal jugular veins is the best choice, at least one should be preserved.

Adult↗

PubMed2001

[An analysis of the results of central masking effect on healthy ears].

OBJECTIVE: To investigate the mechanism of Central Masking Effects(CME) and its effects on audiometry measurement. METHOD: The pure tone threshold was measured when the notest ear was masked or was in quiet respectively. We investigated the different results while giving different level maskers at the same frequency, or giving the same masker at different frequencies to find out their rules. RESULT: The CME has frequency-selective properties and sound level-selective properties. The CME appears apparently at 1 kHz and 2 kHz. At 2 kHz, the CME get the highest. When the masker was lower than 60 dB HL, the CME became higher as the masker was tuned higher; when the masker was 60 dB HL, the CME get the highest[(11.53 +/- 4.38)dB HL]. If the masker was higher than 70 dB HL, overmasking appeared. CONCLUSION: Our observations come to the conclusion that central masking correction should be made clinically when the masker is higher than 40 dB HL. 60 dB HL masker at 2 kHz can make the CME higher than 10 dB HL, thereby can be used to identify false deafness.

Adult↗

PubMed2001

[Application of nasal endoscope in diagnosis and treatment of epistaxis].

OBJECTIVE: To investigate the indication for diagnosis and treatment of epistaxis under nasal endoscope. METHOD: The data of 226 epistaxis cases were analized. Under nasal endoscope: 126 cases were packed, 78 cases were treated with microwave, laser cautery, 42 cases were operated. RESULT: An outstanding visutization was afforded by nasal endoscope and operation conveniencly, diagnosis correctively. CONCLUSION: We think it is an excellent method to examine and treat epistaxis and worthy to be recommented.

Adolescent↗