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Biomedical subjects

W Lim

Publications and source records attributed to W Lim.

64 records · Page 4Linked to original sources
PubMed1988

Penicillium marneffei infection: an underdiagnosed disease?

Penicillium marneffei is a rare human pathogen that often causes problems in clinical and histological diagnosis. A patient who presented with autoimmune haemolytic anaemia and hepatosplenomegaly, and was subsequently found to be suffering from disseminated Penicillium marneffei infection, is reported. The liver biopsy showed epithelioid cell granulomas only, and tuberculosis was initially considered the most likely diagnosis. The correct diagnosis became evident in a subsequent colonic biopsy, which showed extensive infiltration by penicillium-laden macrophages.

Bacterial Infections↗
PubMed1986

The problem of home management in the estimation of the incidence of acute myocardial infarction from hospital records.

Past studies of the incidence of acute myocardial infarction (AMI) have found information for patients managed at home difficult and expensive to obtain. This study attempted to find whether the efficiency of gathering this information could be improved, or if this group of patients could be neglected entirely. A random sample of 270 doctors in Perth were asked about their management of cases of suspected AMI at home. Of these doctors, 78% said that they never managed AMI at home; excluding such doctors before seeking voluntary notification of new cases managed at home could make population surveys of AMI more efficient. For patients under 65 it was estimated that about 1% or less of non-fatal cases meeting World Health Organization criteria for definite AMI were managed at home. Thus neglecting this group would probably cause little bias in computing incidence rates for AMI in Perth.

Acute Disease↗
PubMedDate not supplied

Multiple ischemic infarcts in a child with AIDS, varicella zoster infection, and cerebral vasculitis.

A 4 1/2-year-old girl with acquired immunodeficiency syndrome and prolonged varicella zoster virus skin infection developed multiple ischemic strokes and radiologic and histopathologic evidence of central nervous system vasculitis. Typical features of acquired immunodeficiency syndrome encephalitis were not present and there was no evidence of vasculitis outside the nervous system. Central nervous system vasculitis probably resulted from varicella zoster virus infection that persisted because of immunodeficiency. This acquired immunodeficiency syndrome complication has only rarely been described in adults and to our knowledge has not been described in children.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

Skin diseases in children with HIV infection and their association with degree of immunosuppression.

Since the recognition of the acquired immunodeficiency syndrome (AIDS) in 1981, several dermatologic manifestations have been associated with the syndrome, including candidiasis, dermatophyte infection, molluscum contagiosum, herpes simplex and zoster, bacterial infection, and malignancy. Skin diseases have been observed in both the adult and the pediatric human immunodeficiency virus (HIV) infection in an academic hospital setting in relationship to the current CDC classification of pediatric HIV infection. The severity of dermatologic manifestations is correlated with the immune status of the patients. The latter was determined by T4 helper cell numbers and lymphoproliferative responses to mitogens and recall antigens. More severe T helper cell depletion was associated with a wider spectrum and increased severity of dermatologic manifestations.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

Prevalence of hepatitis C infection in Hong Kong.

A study of a cross-section of the Hong Kong Chinese population was done to investigate the seroprevalence of hepatitis C. Healthy subjects were random visitors of a health exhibition, while clinical subjects were recruited from an outpatient liver disease clinic, sexually transmitted disease clinics, dialysis centres and drug rehabilitation centres. A total of 910 subjects were tested. The assay kits were from Abbott and Ortho laboratories. Of the general population, 0.5% was found to be positive for antibody to hepatitis C (anti-HCV). Suspected chronic non-A non-B patients, parenteral drug abusers and haemophiliacs shared a common high (up to 70%) prevalence of anti-HCV. Sexual partners of index patients, homosexuals and female prostitutes as well as hepatitis B carriers had 0% prevalence. It was concluded that parenteral and blood product exposures were the two main risk factors for hepatitis C.

Adolescent↗