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Biomedical subjects

W Lawson

Publications and source records attributed to W Lawson.

At least 127 records · Page 7Linked to original sources

Ethmoid sinus disease: CT evaluation in 400 cases. Part III. Craniofacial resection.

Of 400 patients with ethmoid sinus disease, 18 had undergone craniofacial resection. This operation is an aggressive surgical procedure directed at total en bloc extirpation of tumors that extend through the floor of the anterior cranial fossa. Recent advances in surgical technique have made it the procedure of choice for sinonasal tumors that extend through the cribriform plate, fovea ethmoidalis, and orbital roof. Specifically, this operation has had excellent results in patients with esthesioneuroblastomas. Radiologists must be aware of the possible pitfalls in interpreting the postoperative computed tomographic scans and the findings that suggest tumor recurrence.

Carcinoma↗

Complications of hyperbaric oxygen in the treatment of head and neck disease.

Hyperbaric oxygen has been advocated in the treatment of many head and neck diseases. Reports of such treatments have described eustachian tube dysfunction as the only complication. A review of patients receiving hyperbaric oxygen for head and neck diseases at The Mount Sinai Medical Center revealed serious complications, which included seizure, stroke, and myocardial infarction. In addition, follow-up study of these patients demonstrated that 11 patients treated for radiation-induced necrosis had an undiagnosed recurrence of cancer.

Adult↗

Effect of molindone on weight change in hospitalized schizophrenic patients.

A retrospective review was conducted to assess the effect of molindone on weight. Monthly weights and neuroleptic dosages during the first three months of psychiatric hospitalization were compared between matched groups of patients receiving molindone, a combination of molindone and other neuroleptics, or other neuroleptic drugs. We found no significant differences in weight gain among the three groups. Our results challenge the common opinion that molindone can be associated with a lack of weight gain compared to other antipsychotics.

Adult↗

Partial laryngectomy for vocal cord cancer with marked limitation or fixation of the vocal cord.

Partial laryngectomy was the procedure utilized to treat 26 patients with either marked limitation of vocal cord motion or fixation. The absolute 24-month tumor free control rate was 73% (19 of 26). Extended hemilaryngectomy with cricoid resection should be performed if subglottic extension of 5 mm or greater is present. Extended hemilaryngectomy has a greater complication rate than the classical hemilaryngectomy.

Cricoid Cartilage↗

The coexistence of myofascial pain dysfunction and mucoepidermoid carcinoma of the parotid gland: report of case.

A case history of a patient who was being treated for myofascial pain dysfunction and later was found to have mucoepidermoid carcinoma of the parotid gland is presented. The clinical and radiologic diagnosis is described. The need for considering differential diagnoses for both TMJ disorders and diseases of the soft tissue surrounding the joint is emphasized, as are consultations and follow-up examinations.

Adult↗

Posttraumatic pseudoaneurysm of the extracranial middle meningeal artery.

Pseudoaneurysms of the extracranial arterial tree are uncommon. To our knowledge, four cases of pseudoaneurysm of the internal maxillary artery have been reported, but there have been no reports of pseudoaneurysm of the extracranial segment of the middle meningeal artery. A 15-year-old girl, who suffered a gunshot wound in the right maxillary region, suffered a pseudoaneurysm of the proximal portion of the middle meningeal artery, as shown by carotid angiography six days after injury. The lesion was successfully treated with absorbable gelatin sponge embolization. Treatment of pseudoaneurysms reduces the risk of hemorrhage from subsequent rupture. Although these lesions are amenable to surgery, transvascular embolization or mechanical interruption appears to be simpler and equally effective.

Adolescent↗

A mucocele of the submandibular gland.

We encountered an unusual case of a mucocele arising from the submandibular gland. Among the limited number of cystic salivary gland neoplasms reported in the literature, there have been no reports, to our knowledge, of a similar cystic lesion. The unique characteristics of this mass permitted definitive diagnosis by computed tomographic scanning.

Adenolymphoma↗

Extracranial tumor vascularity: determination by dynamic CT scanning. Part II: The unit approach.

Twenty-eight patients had combined conventional drip infusion CT scans. The information about the anatomic location of the lesion, its configuration, its cross-sectional appearance, its vascularity (as determined by dynamic signature curves), and its clinical presentation were considered as a single overall unit. This diagnostic approach allowed a diagnosis to be made on virtually all of these enhancing lesions without resorting to either a digital venous imaging study or angiographic procedure. In 17 of these cases, such an invasive second procedure was performed either to confirm the CT impression as part of this study or as part of a therapeutic embolization procedure.

Adolescent↗

Extracranial tumor vascularity: determination by dynamic CT scanning. Part I: Concepts and signature curves.

Combined conventional drip infusion-dynamic CT scanning was performed on 28 patients with clinically discovered neck or parapharyngeal space masses. Seventeen of these also had digital venous study or angiographic studies either to confirm the CT diagnosis or as part of an embolization procedure. The studies indicate that the initial portion of the dynamic scan curve can be characteristically classified as either an arterial, venous, or hypovascular signature curve. The current ideas of how these curves are generated, the specific appearance of these signature curves, and the types of pathologic conditions that correlate with each curve are discussed.

Angiography↗

Laser lateralization for bilateral vocal cord abductor paralysis.

Unilateral laser excision of the thyroarytenoid muscle combined with suture lateralization of the vocal ligament was successful in 13 of 14 patients (93%) treated for bilateral abduction immobility sufficient to require tracheotomy. Among the four patients requiring revision surgery, three had cricoarytenoid fixation and one had vocal cord paralysis. All patients had a satisfactory voice after surgery. The anesthetic management of laser microsurgery is discussed.

Adult↗

Bilateral nasal bone osteophytosis associated with short-term oral isotretinoin therapy for cystic acne vulgaris.

Bilateral 2.5 and 3.0 mm nasal bone osteophytes developed five weeks following the initiation of oral isotretinoin therapy (50 mg daily) for severe cystic acne vulgaris in a healthy 30-year-old white woman who had undergone uneventful rhinoplasty 12 years earlier. Histologically mature bone fragments were removed at surgery. Vitamin A and its analogs have been reported to cause hyperostosis of the vertebrae and long bones, but no known reports link them to nasal bone changes. Clinically significant nasal bone osteophytosis may be another adverse reaction to oral isotretinoin therapy.

Acne Vulgaris↗

The hidden antral compartment.

Two patients with rare isolated posterior antral compartments are presented. In both cases, the radiologist directed the surgeon to these clinically hidden recesses. The radiographic appearance included a walled-off compartment filled with material of soft-tissue density; clinical importance is discussed.

Adult↗

Parapharyngeal space masses: an updated protocol based upon 104 cases.

Surgical and CT examinations of 104 patients, each of whom presented with a parapharyngeal space mass, has resulted in the development of an updated CT protocol designed to provide a preoperative diagnosis. When dynamic scanning is used, diagnostic angiography or digital venous imaging (DVI) can be avoided in almost all of these cases. A specific preoperative diagnosis can be made in 88% of the patients and a limited differential diagnosis, which includes the final diagnosis, can be made in virtually all cases. The protocol and the problems encountered in differential diagnosis are presented. Evidence to suggest that minor salivary gland benign mixed tumors may arise in salivary rest tissue, rather than pharyngeal mucosal glands, is also presented.

Diagnosis, Differential↗

Radiographic findings in progressive necrotizing "malignant" external otitis.

Twenty-three cases of progressive necrotizing (malignant) external otitis were reviewed. Radiographic evaluation was correlated with clinical disease. CT scanning accurately demonstrated subtle foci of involvement in the skull base which may be clinically unsuspected or go undetected with other studies. Central skull base erosion indicates advanced disease and selects those patients requiring extended antibiotic therapy. Soft tissue thickening of the parapharyngeal space and roof of the nasopharynx also implies advanced disease requiring prolonged therapy. Soft tissue improvement can be visualized on CT. While CT scanning demonstrates the progression of bony disease, it cannot be used to follow resolution of central skull base osteomyelitis. Radionuclide scans provide information regarding the overall extent of the inflammatory process.

Aged↗

Total glossectomy. A technique of reconstruction eliminating laryngectomy.

A series of 15 patients undergoing total glossectomy for advanced carcinoma of the tongue was analyzed with regard to operative management, oral reconstruction, rehabilitation of deglutition and speech, and survival. While patients often underwent elective total laryngectomy to prevent aspiration previously, a method of laryngoplasty has now been devised that permits retention of the larynx with preservation of swallowing and speech. This technique of laryngoplasty may be used for the management of chronic aspiration of any cause.

Aged↗