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Biomedical subjects

W Kreuzer

Publications and source records attributed to W Kreuzer.

At least 19 recordsLinked to original sources
PubMed2003

Sentinel lymph node detection with large human serum albumin colloid particles in breast cancer.

Detection of metastatic involvement of lymph nodes is essential for management and prognostic evaluation in breast cancer patients. The success of lymphatic mapping depends on identifying the sentinel lymph node(s) draining the primary tumour. However, when mapping is performed with a radiocolloidal agent, the number of hot lymph nodes varies with the agent and its size, among other factors. In this study, we evaluated prospectively the detection rate of sentinel lymph nodes in breast cancer when injecting large particles (100-600 nm) of human serum albumin colloids (Senti-Scint). In 128 consecutive breast cancer patients without palpable lymph nodes, pre-operative static lymphoscintigraphic mapping of the breast was performed after subcutaneous injection of 15 MBq of the radiocolloid. Lymphoscintigrahic results were compared with intra-operative surgical gamma detection probe and blue dye mapping data. Pre-operative lymphoscintigraphy and surgical gamma detection probe both correctly detected 203 sentinel lymph nodes in 122/128 patients (95%), while blue dye mapping showed only 183 sentinel lymph nodes in 82% of the patients. Only one or two sentinel lymph nodes were identified in each patient, which allowed the surgeon easily to find the sentinel lymph node(s) intra-operatively. In conclusion, lymphoscintigraphy with large particles of human serum albumin colloids is a helpful and reliable procedure for the surgical management of breast cancer.

Adult↗
PubMed1989

[12-year experience with continuous peritoneovenous shunt in the treatment of therapy-resistant ascites and hepatorenal failure: benefits and pitfalls].

Theoretical advances using the peritoneovenous shunt were proven in clinical practice over a 12-year period of experience with this system. Continuous reinfusion of protein- and electrolyte-rich ascitic fluid improves the circulating plasma volume and seems to avoid hepatorenal syndrome. The quality of life is improved by the significant decrease in weight and ascitic volume: long-time survival seems to be improved when compared with patient groups without treatment by continuous peritoneovenous shunt. Use of the system in patients with malignant ascites does not seem to be encouraging. Fatal postoperative coagulopathy can be avoided by the administration of proteinase inhibitors. Operative mortality was 0%, hospital mortality was 23%. The system became defective in 23%, 12% caused by intra-operative technical failures.

Ascites↗
PubMed1983

[Therapy of esophageal varices using flexible endoscopes].

Fibroendoscopic sclerotherapy of esophageal varices during or after a bleeding period is an effective method with low risks. From 1977 to June 1981, 60 patients underwent 125 sclerotherapy sessions. In 61,5% this palliative therapy had good results. 27% died during the first stay in hospital, 11,5% of them due to severe attacks of bleeding. Another 11,5% had rebleeding episodes later on. The complication rate of this method is 0,9%, the mortality rate 0%.

Esophageal and Gastric Varices↗
PubMed1981

[Portal hypertension and chronic renal insufficiency. Successful treatment with hemodialysis].

We present three cases with portal hypertension, ascites and concomitant chronic renal failure, successfully treated for 38, 26 and 5 months respectively with chronic hemodialysis. The causes of portal hypertension were alcoholic cirrhosis of the liver in 2 cases and cavernous transformation of portal vein with intrahepatic block, in one case. The complications of portal hypertension, the conservative and surgical treatment of oesophageal varices and ascites are discussed.

Adult↗
PubMed1980

[Carcino-embryonic antigen as screening protein in the follow-up of patients with surgically-treated gastrointestinal cancer (author's transl)].

Carcino-embryonic antigen (CEA) was determined in 206 patients with gastrointestinal cancer (131 colonic and 75 stomach) at the 2nd Department of Surgery of the University of Vienna. The value of CEA in predicting tumour recurrence and/or metastatic spread has been assessed within the framework of regular follow-up control examinations after surgery. A postoperative rise in CEA titre corresponded with cancer recurrence or metastasis both in patients with stomach (91%), as well as colonic cancer (86%), whilst low postoperative CEA values correlated with a negative clinical report only in patients with carcinome of the colon to any degree of accuracy (91%). The correspondence was much lower in patients with stomach cancer (67%).

Carcinoembryonic Antigen↗
PubMed1979

[Modern functional and physiological techniques in abdominal surgery (author's transl)].

The increasing importance of physiological and functional surgical procedures in the surgical therapy of benign abdominal disease is implied. Positive results were achieved at the 2nd Department of Surgery of the University of Vienna following parietal cell vagotomy in hypersecretory gastroduodenal ulcer, latero-lateral pancreatico-jejunostomy according to Puestov-Mercadier in chronic relapsing pancreatitis, distal splenorenal shunt according to Warren in portal hypertension and following peritoneo-venous shunt according to Warren in portal hypertension and following peritoneo-venous shunt according to Le Veen in ascites and cirrhosis of the liver.

Abdomen↗
PubMed1979

[Significance of alpha 1-acid glycoprotein for the diagnosis of stomach cancer (author's transl)].

In 41 patients with benignant and malignant diseases of the stomach the appearance of alpha 1-acid glycoprotein (alpha1sGP) in the gastric juice was recorded quantitatively by radial immunodiffusion and compared with normal serum alpha1sGP by immunelectrophoretic analyzation and by immunodiffusion after after Ouchterlony. In 80.0% of the patients with carcinoma, in 11.8% of patients with gastric or duodenal ulcer and in 28.6% of the patients with gastritis the presence of alpha1sGP could be evidenced in the gastric juice. The appearance of this glycoprotein significantly differed in benignant and malignant diseases of the stomach. A polymorphism of the stomach alpha1sGP compared with normal serum alpha1sGP could not be established by the applied methods. Therefore it is unprobable that the gastric alpha1sGP is originated by the malignoma.

Diagnosis, Differential↗
PubMed1979

[The Le Veen peritoneo-jugular shunt and the testing of its function].

A radioisotope technique for testing the patency of, peritoneo-venous shunts of Le Veen, is reported and is demonstrated by discussing a case history. By now a total number of 16 patients have been tested, after implantation of such a shunt. The demonstrated radioisotope technique, which causes no complaints from the patient, is not only able to inform concerning the functional state of the Le Veen shunts, but also, in case of disturbances, is able to reveal the cause of the underlying malfunctions.

Ascites↗