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Biomedical subjects

W Kehrl

Publications and source records attributed to W Kehrl.

47 records · Page 3Linked to original sources
PubMed1992

[Dose-finding study for hyperfractionated, accelerated radiotherapy plus simultaneous carboplatin administration in patients with locoregionally advanced head and neck cancer].

Therapy of large inoperable squamous cell-carcinomas of the head and neck is considerably problemful. Combined simultaneous radio-chemotherapy with carboplatin and radiotherapy with hyperfractionated accelerated radiation is small effective than conventional monofractionated radiotherapy alone and may reduce side effects. Aim of the following study was dosage optimisation of the applicated carboplatin.

Carboplatin↗
PubMed1992

[The ototoxicity of the cytostatic drug carboplatin in patients with head-neck tumors].

The side effects of the anti-cancer drug carboplatin on the cochlea in 65 patients with head and neck cancer were examined in the present study. A possible dependence of ototoxicity on the patient's age, the effect of pre-existing audiometric changes and the carboplatin dose were investigated. A therapy-induced sensory hearing loss was found in 32% of the patients. The average hearing loss was 15 dB and primarily involved the frequency ranges from 4 to 8 kHz. The degree of the hearing defects incurred was not influenced by the patient's age or pre-existing hearing defects but depended on the carboplatin dose used. The severity of carboplatin cochlear ototoxicity was moderate, so that no patient suffered a lack of hearing that was of social significance.

Aged↗
PubMed1992

[Ultrasound diagnosis of isolated vagus neurofibroma in Recklinghausen disease].

We report on an isolated cervical vagus nerve neurofibroma in a patient with neurofibromatosis Recklinghausen. B-scanechography showed a well limited tumor without infiltration of adjacent structures and with cranial and caudal dendrites. The inner structure of the neurofibroma was characterized by a homogenous picture of low ultrasound reflection. Although ultrasound allows an exact description of the tumor's topography, it is impossible to give a histological interpretation by the sonomorphology.

Adult↗
PubMed1991

[High-caloric nutrition in radiochemotherapy, nasogastric tube and parenteral nutrition versus PEG (percutaneous endoscopic controlled gastrostomy)].

The advantages and problems of different types of artificial feeding are discussed. For patients needing long-term nutritional support, we see the following special advantages of PEG: physiological enteral nutrition with an only small risk of tube dislocation, no additional handicap of the natural swallowing procedure and without stigmatizing the patient by an external visible tube (Tab. 3). To help to spread this method of artificial feeding for the benefit of the patient, this article gives some informations on how to cope with the problems that might occur when using PEG (for example: a diet plan for building up the tube food nutrition (Tab. 4).

Antineoplastic Agents↗
PubMed1991

[Interventional angiography in the ENT field].

Development of new micro catheters and digital technique of angiography today allows a superselective angiography of small vessels of the external carotid artery. Therapeutical and diagnostical possibilities for ENT will be discussed.

Adolescent↗
PubMed1990

[Tumors of the parapharyngeal space. Topographical anatomy, diagnosis, therapy, literature review].

The borders of the parapharyngeal space are formed of fasciae of muscular tissue. Its lateral border is formed by the bone of the mandible, while its cranial border is formed by the petrous bone. The initial symptoms of parapharyngeal tumors are diagnostically volatile because of the soft tissue contents of the parapharyngeal borders. For diagnostic reasons, it has to be decided whether to extirpate tumor immediately in order to obtain a specimen for histological evaluation or whether extensive presurgical examinations are necessary. Aside from multiple serological investigations for infectious diseases, these include all kinds of noninvasive morphological procedures such as CT scan, MR scan, transcutaneous and endoscopic B-mode sonography. In addition, invasive procedures such as arterial angiographies and the taking of specimens may be necessary in some cases.

Diagnostic Imaging↗
PubMed1990

[Neurofibromatosis in the ENT field].

As the neurofibromatosis does not only show on the neuroderm, but also on the mesoderm, all tissues and organs of the human body can be affected. A central and peripheral form is known. Classical symptoms and major diagnostic criteria will be described. The therapy will be illustrated on four cases.

Adolescent↗
PubMed1990

[Elongated styloid process as a cause of dysphagia].

An elongated styloid process or a calcified stylohyoid ligament may cause dysphagia or craniofacial and cervical pain. Palpation and radiography confirm the diagnosis provided that it is considered. The only effective treatment is surgery. Eleven patients undergoing surgery for elongated styloids or calcified ligaments are reported. In all cases the symptoms disappeared or were relieved. An evaluation of the external versus the transoral approach is presented. The authors recommend the external one, as it provides adequate anatomical exposure of the styloid process and its relationship to the structures of the parapharyngeal space.

Adult↗
PubMed1988

[Differential diagnosis of parapharyngeal tumors--the vagus neurinoma].

Among the tumours of the head and neck, only a small percentage is located in the parapharyngeal space. These are divided into salivary gland, neurogenic and so-called miscellaneous tumours. Two cases of vagus neurinoma are reported, and the diagnostic and therapeutic aspects are discussed. The neoplasms usually grow to a large size before they are treated, because they grow slowly and the signs and symptoms are non-specific. A latero-cervical approach is recommended for extirpation for diagnostic purposes.

Aged↗
PubMedDate not supplied

The total reconstruction of the tympanic membrane by the "crowncork" technique.

PURPOSE: The "crowncork tympanoplasty" is a technique for the total reconstruction of the tympanic membrane. It is recommended in cases of ear malformation, blunting phenomena, and total deficiency of the membrane caused by chronic otitis media. PATIENTS AND METHODS: The records of 12 patients undergoing "crowncork tympanoplasty" were reviewed. This includes 5 patients who were operated on because of middle ear malformation, 6 cases with a blunting phenomena following prior tympanoplasty, and 1 patient with chronic otitis media. RESULTS: In each case an intact tympanic membrane was achieved. The air bone was reduced to 17, 19, 16, and 11 dB in the frequency 500, 1,000, 2,000, and 4,000 Hz. CONCLUSION: The use of cartilage for tympanoplasty has been useful despite the comparatively worse vibration characteristics of the rigid material. Total reconstruction of selected problem cases using this "crowncork technique" has resulted in good healing with favorable hearing results and should be incorporated into the routine of the skilled otosurgeon.

Adult↗