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Biomedical subjects

W K Yee

Publications and source records attributed to W K Yee.

4 recordsLinked to original sources

Intravenous radionuclide total body arteriography: a new technique.

We have developed a technique using a blood pool agent Tc-99m labeled red blood cells and a detector head set moving at a high speed to obtain total body arterial and blood pool images with only a single intravenous injection. Previously with an intravenous radiotracer injection, only regional arterial images could be obtained. Now, with this simple, non-invasive technique, we can evaluate the major arterial system, organs, and soft tissues in the whole body, as well as cardiac function. On reviewing 500 cases, more than 90% of the first-pass arterial phase images clearly demonstrated the aorta, ilio-femoral arteries, and, to a lesser extent, the more distal arteries in the lower extremities. The second-pass blood pool images revealed the anatomical and morphological status of the solid organs, as well as perfusion changes in various organs and soft tissues.

Adult↗

IV radionuclide total-body arteriography: a new noninvasive whole-body screening procedure--a case report.

Recently the authors introduced a new technique of intravenous (IV) radionuclide total-body arteriography. The major arterial system, multiple organs of the whole body, and cardiac function can be evaluated with one small IV injection in the arm. After analyzing more than 1000 cases, they have found that many pathologies can be detected and/or confirmed in this procedure. This new technique may be used as a general whole-body screening test for those patients at high risk for disease.

Aged↗

Reevaluation of plain radiographic findings in the diagnosis of aortic rupture: the role of inspiration and positioning on mediastinal width.

Despite the advent of newer imaging modalities, conventional radiography and clinical examination remain the primary screening method in evaluation of the mediastinum following blunt thoracic trauma. Mediastinal width (MW) is generally considered an important finding in assessing for aortic rupture. The degree of inspiration and patient positioning clearly affects MW, but is largely ignored in the literature. This study investigates the mediastinal widths of normal volunteers with differing degrees of inspiration and positioning, and compares them to radiographs of patients with known aortic ruptures. Mediastinal widths were obtained from chest radiographs of 16 patients with known aortic rupture, and from 50 volunteers using AP-inspiratory-supine, AP-expiratory-supine, and PA-inspiratory-upright technique. Upper 95% confidence limits were obtained for normals. A statistically significant difference in MW of normals was found between inspiratory-supine, expiratory-supine, and upright-inspiratory techniques. Compared to the same degree of inspiration in normals, 12 of 16 patients with aortic rupture had a MW above the upper 95% confidence limits. It is concluded that mediastinal width in normals is significantly affected by the degree of inspiration and positioning. When comparing mediastinal widths for normals and ruptures, there was a significant difference in MW for most degrees of inspiration. As depth of inspiration increased, differences between MW in controls and rupture patients increased. We conclude that patient positioning and degree of inspiration are important factors in assessing the mediastinum, and every effort should thus be made to obtain an upright-inspiratory film if clinically feasible prior to declaring a mediastinum as abnormal.

Adolescent↗