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Biomedical subjects

W K Smith

Publications and source records attributed to W K Smith.

66 records · Page 4Linked to original sources

Analgesic effect of an aspirin-codeine-butalbital-caffeine combination and an acetaminophen-codeine combination in postoperative oral surgery pain.

The efficacy of an aspirin-caffeine-codeine-butalbital combination was compared to an acetaminophen-codeine combination and placebo in outpatients who had moderate or severe pain after the surgical removal of impacted third molars. Using a self-rating record, patients rated their pain, relief, anxiety and relaxation hourly for up to 6 hours after medicating. Each active medication was significantly superior to placebo for measures of analgesia and relaxation. Although the butalbital-containing combination provided consistently greater analgesia, the differences between active medications were not statistically significant. The acetaminophen-codeine combination significantly reduced anxiety; however, the butalbital containing combination did not. The results of this study suggest that female patients may have greater efficacy than male patients. All adverse effects were transitory and consistent with the known pharmacologic profiles of the study medications or the backup analgesic.

Acetaminophen↗

Use of computed tomography for a three-dimensional treatment planning system.

Computed tomography (CT) can generate a set of serial contiguous slices which form a volume of medical image data. We have developed new techniques for creating computer synthesized 3-D images directly from a volume encoded as a three-dimensional array. The operator can place the eye anywhere in object space to selectively view a portion of the volume from any angle. A set of volume processing tools have been recently developed to allow interactive manipulation of image data within the volume. These tools allow the system to be used for surgical planning, and craniofacial implant design.

Image Processing, Computer-Assisted↗

A data exchange format for neuroanatomy workstations.

The development of the microprocessor has enabled biomedical researchers to use powerful computers as single user workstations. Many such systems are now in use--some developed for use within individual laboratories, and others purchased commercially. These systems typically mix computer graphics and image processing capabilities. No standard exists that allows users of these workstations to exchange anatomical data in graphical or image form. This paper considers issues involved in designing a flexible format for exchanging digital anatomical data between laboratories.

Animals↗