Biomedical subjects

W K Laskey

Publications and source records attributed to W K Laskey.

76 records · Page 5Linked to original sources

PubMed1979

Assessment of left ventricular function in aortic insufficiency using echocardiography, gated scintigraphy and contrast angiography.

Echocardiography, gated scintigraphy and contrast angiography were used to measure left ventricular ejection fractions in 20 patients with varying degrees of aortic insufficiency. There was good correlation between the radionuclide and the angiographic ejection fractions. Echocardiographic ejection fraction correlated less well with the angiographic ejection fraction. The radionuclide left ventricular ejection fraction may prove valuable in the noninvasive serial evaluation of left ventricular function in patients with chronic aortic insufficiency.

Adult↗

PubMed1979

Canine blastomycosis as a harbinger of human disease.

Blastomycosis occurred in six patients in five households. In each instance one or more dogs living with the family or living near the family also developed blastomycosis. The recognition of canine blastomycosis helped in the early diagnosis of human cases. Because both dogs and patients were probably infected at the same place, canine blastomycosis may be an important epidemiologic marker, alerting physicians to the possible presence of concomitant blastomycosis in humans.

Adolescent↗

PubMed1979

Radionuclide left ventricular dV/dt for the assessment of cardiac function in patients with coronary disease.

To investigate potential uses of left-ventricular (LV) systolic ejection rate (LV dV/dt) in the evaluation of LV function, we examined the effect of exercise, angiotensin, and leg raising on LV ejection fraction and LV dV/dt in patients with coronary-artery disease. The following observations were made: a) LV ejection fraction and dV/dt changed proportionately, but in opposite directions, during supine exercise; b) LV ejection fraction and dV/dt decreased to a similar extent during angiotensin infusions; and c) LV ejection fraction and dV/dt were unchanged by leg raising. The changes in peak and mean LV dV/dt were similar. Regardless of the physiologic state, peak LV dV/dt occurred during the first third of systole. These data imply that in this population there were no specific advantages of LV dV/dt over LV ejection fraction in the evaluation of LV performance.

Angiotensin II↗

PubMedDate not supplied

Coronary MRA: use in assessing anomalies of coronary artery origin.

PURPOSE: The purpose of this work was to describe the use of coronary MR angiography (MRA) in the clinical evaluation of a series of patients with anomalous origin of the coronary arteries suspected on coronary angiography. METHOD: Eight patients underwent coronary MRA to further define variant coronary anatomy that was found on coronary angiography. A 2D segmented k-space gradient echo sequence was used with breath-holding. MRA images were assessed for traversal of an anomalous artery between the aorta and pulmonary artery trunks, which carries the greatest clinical significance. RESULTS: Of six patients with anomalous origin of the right coronary artery on angiography, two were shown by MRA to have an interarterial course of the anomalous vessel. Neither of two left coronary arteries with ectopic origin coursed between the great arteries, although one passed through the septum. CONCLUSION: Coronary MRA is a useful adjunctive technique to angiography in the evaluation of the relationship of anomalous coronary arteries to the great arteries.

Adult↗