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Biomedical subjects

W K Bottomley

Publications and source records attributed to W K Bottomley.

At least 37 records · Page 2Linked to original sources
PubMed1979

General legal aspects of diagnostic dental radiography.

Recent concern about the effect of ionizing radiation on man has focused attention on the frequent use of diagnostic radiographs in dentistry. The clinician is expected to conduct his actions according to guidelines which reflect new information and changing technology in diagnostic dental radiography. Failure to do so may have severe legal consequences. Protection of the patient must be a matter of normal course, for each time the federal or state governments legislate toward safety in the healing arts, health professionals lose credibility and the confidence of the public. Implications of the federal radiation protection guidelines are discussed.

Dental Records↗
PubMed1978

Pulmonary nocardiosis associated with primary nocardial infection of the oral cavity.

A case of pulmonary nocardiosis associated with primary nocardial infection of the oral cavity in a compromised host is presented. Nocardia asteroides, an aerobic, gram-positive, branching, filamentous fungus, was demonstrated in the sputum and in pathologic specimens from gingival sulci stained by Gram's method and the acid-fast method Kinyoun. The organism was identified in cultures made on Sabouraud's glucose agar. Marked clinical improvement was noted when the patient received high dosage of sulfisoxazole diolamine (8 to 12 Gm. per day) for a prolonged period of time (9 to 12 months). Because of an apparent relative increase in the incidence of nocardiosis and a paucity of information on the subject in the dental literature, this article is timely.

Adult↗
PubMed1978

The use of water-soluble bioflavonoid-ascorbic acid complex in the treatment of recurrent herpes labialis.

The efficacy of a water-soluble bioflavonoid-ascorbic acid complex was evaluated in the treatment of fifty episodes of recurrent herpes labialis. Twenty episodes were treated with a complex of 600 mg. of water-soluble bioflavonoids and 600 mg. of ascorbic acid, administered in equal increments three times daily. Twenty episodes were treated with a complex of 1,000 mg. of water-soluble bioflavonoids and 1,000 mg. of ascorbic acid, administered in equal increments five times daily. Ten episodes were treated with a lactose placebo. The therapeutic regimen was maintained for 3 days after the recognition of the initial symptoms associated with recurrent herpes labialis. The water-soluble bioflavonoid-ascorbic acid complex was observed to reduce vesiculation and to prevent the disruption of the vesicular membrane. The therapeutic measure was found to be most effective when initiated during the prodomal stage of the disease process. Optimum remission of symptoms was observed in 4.2 +/- 1.7 days with the 600 mg. dosage of the water-soluble bioflavonoid-ascorbic acid complex. No adverse reactions were reported by any of the patients who participated in this investigation.

Ascorbic Acid↗
PubMed1977

Management of patients with myasthenia gravis who require maxillary dentures.

Some signs of myasthenia gravis can be clearly identified in the oral cavity. The patient with progressive neuromuscular impairment may seek consultation because of dysphagia, impaired mastication, and dysarthia. The dentist should understand the pathophysiology of the symptoms and treat the myasthenic patient accordingly.

Aged↗
PubMed1977

Antineoplastic agents and their oral manifestations.

The use of antineoplastic agents is rapidly increasing. A general classification of these drugs and their mechanisms of action is presented. Many of the drugs have an adverse effect on oral tissue, and the practicing dentist today must be well acquainted with these effects. A discussion of the features of these reactions and their management is presented.

Antineoplastic Agents↗
PubMed1976

Antibiotic prophylaxis for endocarditis in patients with a prosthetic heart valve.

A review of the types of organisms and their sensitivities to antibiotics, as well as the source of infection, was carried out for 11 patients who had late onset infective endocarditis and a prosthetic heart valve. Candida organisms were isolated from two patients. In nine patients with late onset bacterial endocarditis, the organisms isolated were five streptococci and four staphylococci. Their sensitivities to antibiotics were penicillin, five of eight; erythromycin, eight of eight; and cephalothin, six of seven. Two patients with endocarditis had ulcerations beneath their dentures, and one had undergond a prior dental procedure. Of 52 healthy patients with prosthetic valves who were interviewed, only 18 had visited a dentist during the previous year, and six did not receive antibiotic prophylaxis for endocarditis. It is concluded that patients with prosthetic heart valves do not practice good oral hygiene and, if they do visit the dentist, some may not receive antibiotics for endocarditis prevention. An antibiotic regimen for endocarditis is presented that is consistent with the organisms found in the oral cavity and those found in patients with endocarditis who have a prosthetic valve.

Anti-Bacterial Agents↗