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W Jurecka

Publications and source records attributed to W Jurecka.

At least 55 records · Page 3Linked to original sources
PubMed1989

[Pachydermoperiostosis. Clinical aspects, classification and pathogenesis].

There are 2 different forms of the rare disorder of connective tissue "pachydermoperiostosis": a primary form called Touraine-Solente-Gole (TSG) syndrome, and a secondary one, called Bamberger-Pierre-Marie syndrome (BPM). The manifestations of the two forms are very similar, but differential diagnosis is possible because BPM syndrome occurs in association with certain diseases of internal organs and effective treatment of these is followed by regression of the skin manifestations. Therefore, it seems reasonable merely to refer to primary and secondary forms of pachydermoperiostosis, rather than distinctly named syndromes. The pathogenesis of pachydermoperiostosis is unknown. Obviously a hereditary disturbance of metabolism in the connective tissue is involved, and manifestation of the disease can be either primary or secondary as a result of still unknown triggering factors.

Adult↗
PubMed1988

[Lichen ruber ulcerosus. Differentiation from Graham-Little syndrome. Pathogenesis and therapy].

A 61-year-old female patient having suffered for several years from typical Graham-Little's syndrome developed lichen ulcerosus after a period of 9 years. We discuss the relationship between these clinical manifestations with special reference to the pathogenesis and distribution of skin lesions in lichen rubber ulcerosus. Among the numerous therapeutic approaches, treatment with chloroquine or dapsone as well as skin grafting seem to be most promising.

Alopecia↗
PubMed1988

Plexiforme neurofibroma of the skin.

Three cutaneous tumors showing massively thickened nerve fascicles, with a myxomatous matrix in a diffuse tumor mass, were studied by light and electron microscopy, immunohistochemically, and with 3H-thymidine autoradiography. Corresponding to plexiforme neurofibroma, these tumors were called plexiforme neurofibroma of the skin and are compared with nerve sheath myxoma (i.e., cutaneous lobular neuromyxoma, bizarre cutaneous neurofibroma, neurothekoma, and others). In the tumors, a high proportion of perineurial cells (30%) could be detected. Compared with results from regenerating nerves, organized traumatic neuroma, and other types of neurofibroma, these findings show that all constituents of normal peripheral nerves, especially Schwann cells and perineurial cells, may be involved in the growth of peripheral nerve sheath tumors. Furthermore, autoradiography demonstrated a high proliferative activity in one of the tumors. The possible clinical relevance of this finding and the question of whether these tumors may bear a higher risk for malignancy will be discussed.

Adolescent↗
PubMed1988

Disseminated superficial porokeratosis and immunosuppression.

We present a patient who developed skin lesions typical of disseminated superficial porokeratosis (DSP) while on immunosuppressive therapy for pemphigus foliaceus. Phototesting with artificial light sources did not have any effect on the DSP lesions. The literature describing occurrence of DSP on immunosuppression is reviewed and possible pathogenetic mechanisms are discussed.

Aged↗
PubMed1988

[Ichthyosiform scaling in alpha-1,4-glucosidase deficiency].

In two patients suffering from infantile and juvenile types of alpha-1,4 glucosidase deficiency (Pompe's disease, glycogen storage disease types 2a and 2b) with typical lysosomal glycogen storage, widespread dry "ichthyosiform" scaling skin was observed. The clinical and microscopical findings resembled those of ichthyosis vulgaris. Even in the cytoplasm of keratinocytes vacuolar glycogen accumulation was demonstrated, suggesting a correlation between this pathological storage process and the symptom of "scaling". Therefore, ichthyosiform scaling conditions should be investigated not only for disorders of lipid metabolism but also for a possible disturbance of the carbohydrate-digesting enzymes.

Adult↗
PubMed1988

[Pigmented neurofibroma].

In a 24-year-old male melanin synthesis was demonstrated in a neurofibroma by light and electron microscopy. Although it is unclear whether the tumor cells are pigment-synthesizing Schwann cells or whether they originate from a coexisting melanocytic tumor, this tumor again demonstrates the close relationship between peripheral nerve sheath tumors and melanocytic malformations, as for example cellular blue nevi.

Adult↗
PubMed1987

[Specific pregnancy dermatoses--a simplified clinical classification].

The terminology of the specific pregnancy dermatoses is confusing. Several names have been used for the same clinical conditions or individual reports have been described as special entities. In order to get a more practical classification from the clinical point of view, four broad categories of specific dermatoses of pregnancy are proposed: herpes gestationis, polymorphic eruption of pregnancy, prurigo gravidarum and autoimmune progesterone dermatitis.

Autoimmune Diseases↗
PubMed1987

Neurogenic tumors of the skin.

A classification of peripheral nerve sheath tumors in the skin is based on analysis of light-, electron microscopy, immunohistochemistry and cellular composition of the different tumor types. Not only Schwann cells, but also perineurial cells and fibroblasts may be involved in tumor formation. Schwann cell rich and connective tissue cell rich tumors are distinguished. Generally all tumors show low proliferating activity as investigated by H3-Thymidine autoradiography. Only in few connective tissue cell rich tumors higher labelling indices can be demonstrated. These findings are correlated with the clinical course and prognosis of the different tumor types. The question remains, whether connective tissue cell rich tumors are at higher risk for malignant transformation.

Humans↗
PubMed1987

Anthrenus sp. The paraffin block eater bug.

Review of several years-old, paraffin-embedded specimens showed unusual damage, especially of the sectioned surface of hyperkeratotic lesions. The larva of Anthrenus sp., feeding on the embedded material, was identified as the causative agent. Normally found in birds' nests, this species prefers keratin for nutrition, and can therefore damage histopathology collections.

Animals↗
PubMed1986

[Immunoglobulin A in the sebaceous glands. Light and electron microscopy immunomorphologic detection].

This paper presents evidence for the presence of immunoglobulin A in human sebaceous glands. Light- and electron-microscopic immune cytochemistry techniques revealed secretory IgA in normal sebocytes and within pilosebaceous ducts. The secretory process corresponds to the well-established production of IgA at the site of other internal body surfaces. Basal and suprabasal sebocytes contain IgA in linear extracellular, as well as aggregated intracellular patterns. However, maximal diffuse concentrations are present at the opening of the pilosebaceous duct. This distribution pattern indicates an antimicrobial protective character of IgA, corresponding to similar functions on mucous membrane surfaces. Thus, another important humoral factor contributing to the complex system of skin-associated lymphoid tissue is postulated.

Acne Vulgaris↗
PubMed1986

[Generalized argyrosis].

A 58-year-old female patient presented with generalized argyria, caused by abuse of silver-containing tablets for a sore throat for 1.5 years. Diagnosis was confirmed by histology, electron microscopy, and X-ray microanalysis. A therapeutic trial with D-penicillamine was unsuccessful.

Argyria↗