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Biomedical subjects

W Jorde

Publications and source records attributed to W Jorde.

31 records · Page 2Linked to original sources

Pyroglyphid mites, xerophilic fungi and allergenic activity in dust from hospital mattresses.

Dust from mattresses of different composition and age was analysed for mites, xerophilic fungi and allergenic activity. The mites of the genus Demodex were the most abundant (58.2 per cent). Also pyroglyphid mites occurred commonly (36.6 per cent). Pyroglyphid mites were present in small numbers (mean: 1 specimen/0.2 g of dust) in 12 out of the 17 older polyester-foam mattresses. The 11 cotton-horsechair mattresses and the newly used polyester-foam mattresses (three tested) were without them. The dust from the cotton-horsehair mattresses had a significantly higher allergenic activity than from those of polyester-foam. Xerophilic fungi were isolated in three out of 31 mattresses. The species isolated belonged to the genus Aspergillus and Eurotium. E. repens occurred most frequently. Disinfection of mattresses was suggested to have a negative influence on the occurrence of mites and fungi.

Allergens↗

Inhibitory effect of beta-adrenergic stimulants on the histamine reaction in human skin. I. Studies with fenoterol.

In 20 volunteers histamine inhibition by fenoterol (Th 1165 a) was studied. The wheal and erythema reaction caused by intracutaneous application of 5 mug histamine can be inhibited by applying fenoterol in doses from 100--400 mug in form of a metered aerosol on the skin 5 min before the injection of histamine. In this study the dose-reaction effect yielded on ED50 of 140 mug fenoterol.

Adrenergic beta-Agonists↗

[Protective effect of beta-adrenergic substances on the allergic rhinitis (author's transl)].

The protective and curative effect of Th 1165a (Fenoterol) and Salbutamol on the allergic rhinitis is reported. 70 patients with positive nasal provocation tests (speezing, rhinitis and eosinophilia of the secretions) were tested some days later with the same allergen after application of 100 mug TH 1165a. Protective effect could be shown in 64 patients who did not react with clinical symptoms. Another 85 patients were treated in the same way after a positive nasal provocation test and the clinical symptoms disappered within 5 minutes. In 10 patients nasal resistance was measured objectively by bodyplethysmography. Salbutamol showed the same protective and curative effect in 30 patients proved in the same way as described before. Application of the substances in the contralateral nostril had no systemic effect.

Airway Resistance↗